UBP43 (USP18) (NM_017414) Human Untagged Clone
CAT＃: SC114102
USP18 (untagged)-Human ubiquitin specific peptidase 18 (USP18)
CNY 3656.00
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热销推荐Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ISG43; PTORCH2; UBP43 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_017414 edited
GAATTCGGCACGAGGCCTCGTGCCGAATTCGGCACGAGGCTGGAAGTCTGGAGCAGGTGC GCGGCTGCAACGGCAGCCGCGGGAAGCTCGGGCCGGCAGGGTTTCCCCGCACGCTGGCGC CCAGCTCCCGGCGCGGAGGCCGCTGTAAGTTTCGCTTTCCATTCAGTGGAAAACGAAAGC TGGGCGGGGTGCCACGAGCGCGGGGCCAGACCAAGGCGGGCCCGGAGCGGAACTTCGGTC CCAGCTCGGTCCCCGGCTCAGTCCCGACGTGGAACTCAGCAGCGGAGGCTGGACGCTTGC ATGGCGCTTGAGAGATTCCATCGTGCCTGGCTCACATAAGCGCTTCCTGGAAGTGAAGTC GTGCTGTCCTGAACGCGGGCCAGGCAGCTGCGGCCTGGGGGTTTTGGAGTGATCACGAAT GAGCAAGGCGTTTGGGCTCCTGAGGCAAATCTGTCAGTCCATCCTGGCTGAGTCCTCGCA GTCCCCGGCAGATCTTGAAGAAAAGAAGGAAGAAGACAGCAACATGAAGAGAGAGCAGCC CAGAGAGCGTCCCAGGGCCTGGGACTACCCTCATGGCCTGGTTGGTTTACACAACATTGG ACAGACCTGCTGCCTTAACTCCTTGATTCAGGTGTTCGTAATGAATGTGGACTTCACCAG GATATTGAAGAGGATCACGGTGCCCAGGGGAGCTGACGAGCAGAGGAGAAGCGTCCCTTT CCAGATGCTTCTGCTGCTGGAGAAGATGCAGGACAGCCGGCAGAAAGCAGTGCGGCCCCT GGAGCTGGCCTACTGCCTGCAGAAGTGCAACGTGCCCTTGTTTGTCCAACATGATGCTGC CCAACTGTACCTCAAACTCTGGAACCTGATTAAGGACCAGATCACTGATGTGCACTTGGT GGAGAGACTGCAGGCCCTGTATACGATCCGGGTGAAGGACTCCTTGATTTGCGTTGACTG TGCCATGGAGAGTAGCAGAAACAGCAGCATGCTCACCCTCCCACTTTCTCTTTTTGATGT GGACTCAAAGCCCCTGAAGACACTGGAGGACGCCCTGCACTGCTTCTTCCAGCCCAGGGA GTTATCAAGCAAAAGCAAGTGCTTCTGTGAGAACTGTGGGAAGAAGACCCGTGGGAAACA GGTCTTGAAGCTGACCCATTTGCCCCAGACCCTGACAATCCACCTCATGCGATTCTCCAT CAGGAATTCACAGACGAGAAAGATCTGCCACTCCCTGTACTTCCCCCAGAGCTTGGATTT CAGCCAGATCCTTCCAATGAAGCGAGAGTCTTGTGATGCTGAGGAGCAGTCTGGAGGGCA GTATGAGCTTTTTGCTGTGATTGCGCACGTGGGAATGGCAGACTCCGGTCATTACTGTGT CTACATCCGGAATGCTGTGGATGGAAAATGGTTCTGCTTCAATGACTCCAATATTTGCTT GGTGTCCTGGGAAGACATCCAGTGTACCTACGGAAATCCTAACTACCACTGGCAGGAAAC TGCATATCTTCTGGTTTACATGAAGATGGAGTGCTAATGGAAATGCCCAAAACCTTCAGA GATTGACACGCTGTCATTTTCCATTTCCGTTCCTGGATCTACGGAGTCTTCTAAGAGATT TTGCAATGAGGAGAAGCATTGTTTTCAAACTATATAACTGAGCCTTATTTATAATTAGGG ATATTATCAAAATATGTAACCATGAGGCCCCTCAGGTCCTGATCAGTCAGAATGGATGCT TTCACCAGCAGACCCGGCCATGTGGCTGCTCGGTCCTGGGTGCTCGCTGCTGTGCAAGAC ATTAGCCCTTTAGTTATGAGCCTGTGGGAACTTCAGGGGTTCCCAGTGGGGAGAGCAGTG GCAGTGGGAGGCATCTGGGGGCCAAAGGTCAGTGGCAGGGGGTATTTCAGTATTATACAA CTGCTGTGACCAGACTTGTATACTGGCTGAATATCAGTGCTGTTTGTAATTTTTCACTTT GAGAACCAACATTAATTCCATATGAATCAAGTGTTTTGTAACTGCTATTCATTTATTCAG CAAATATTTATTGATCATCTCTTCTCCATAAGATAGTGTGATAAACACAGTCATGAATAA AGTTATTTTCCACAAAAAAAAAAAAAAAAAACTCGAC >OriGene 5' read for NM_017414 unedited
NTGTTCAGATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCCTCGTGC CGAATTCGGCACGAGGCTGGAAGTCTGGAGCAGGTGCGCGGCTGCAACGGCAGCCGCGGG AAGCTCGGGCCGGCAGGGTTTCCCCGCACGCTGGCGCCCAGCTCCCGGCGCGGAGGCCGC TGTAAGTTTCGCTTTCCATTCAGTGGAAAACGAAAGCTGGGCGGGGTGCCACGAGCGCGG GGCCAGACCAAGGCGGGCCCGGAGCGGAACTTCGGTCCCAGCTCGGTCCCCGGCTCAGTC CCGACGTGGAACTCAGCAGCGGAGGCTGGACGCTTGCATGGCGCTTGAGAGATTCCATCG TGCCTGGCTCACATAAGCGCTTCCTGGAAGTGAAGTCGTGCTGTCCTGAACGCGGGCCAG GCAGCTGCGGCCTGGGGGTTTTGGAGTGATCACGAATGAGCAAGGCGTTTGGGCTCCTGA GGCAAATCTGTCAGTCCATCCTGGCTGAGTCCTCGCAGTCCCCGGCAGATCTTGAAGAAA AGAAGGAAGAAGACAGCAACATGAAGAGAGAGCAGCCCAGAGAGCGTCCCAGGGCCTGGG ACTACCCTCATGGCCTGGTTGGTTTACACAACATTGGACAGACCTGCTGCCTTAACTCCT TGATTCAGGTGTTCGTAATGAATGTGGACTTCACCAGGATATTGAAGAGGATCACGGTGC CCAGNGGAGCTGACGAGCAGAGGAGAAGCGTCCCTTTCCAGATGCTTCTGCTGCTGGAGA AGATGCANGACAGCCGGCAGAAAGCAGTGCGGCCCCTGGAGCTGGCCTACTGCCTGCAGA AGTGCAACGTGCCCTTGNNTTGTCCACATGATGCTGCCCAACTGTACCTCANAACTCTGG AACTG >OriGene 3' read for NM_017414 unedited
NACCGCGGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTGTGGAAAATAACTTT ATTCATGACTGTGTTTATCACACTATCTTATGGAGAAGAGATGATCAATAAATATTTGCT GAATAAATGAATAGCAGTTACAAAACACTTGATTCATATGGAATTAATGTTGGTTCTCAA AGTGAAAAATTACAAACAGCACTGATATTCAGCCAGTATACAAGTCTGGTCACAGCAGTT GTATAATACTGAAATACCCCCTGCCACTGACCTTTGGCCCCCAGATGCCTCCCACTGCCA CTGCTCTCCCCACTGGGAACCCCTGAAGTTCCCACAGGCTCATAACTAAAGGGCTAATGT CTTGCACAGCAGCGAGCACCCAGGACCGAGCAGCCACATGGCCGGGTCTGCTGGTGAAAG CATCCATTCTGACTGATCAGGACCTGAGGGGCCTCATGGTTACATATTTTGATAATATCC CTAATTATAAATAAGGCTCAGTTATATAGTTTGAAAACAATGCTTCTCCTCATTGCAAAA TCTCTTAGAAGACTCCGTAGATCCAGGAACGGAAATGGAAAATGACAGCGTGTCAATCTC TGAAGGTTTTGGGCATTTCCATTAGCACTCCATCTTCATGTAAACCAGAAGATATGCAGT TTCCTGCCAGTGGTAGTTAGGATTTCCGTAGGTACACTGGATGTCTTCCCAGGACACCAA GCAAATATTGGAGTCATTGAAGCAGAACCATTTTCCATTCACAGCATTCCGGATGTAGAA CAGTAATGACCGGAGTCTGCCATTCCCACGTGCGCAATCACAGCAAAAGCTCATACTGGC CTTCAGACTGCTNCTCAGCATCACAAGACTCTCGCTTCATTGGAAAGATCTGGCTGAAAT CCAGCTCTGGGGGAAGTCAAGGAGTGCAGAATCTTCTTCTCTGTGAT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_017414 |
| Insert Size | 2300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_017414.2, NP_059110.2 |
| RefSeq Size | 2054 bp |
| RefSeq ORF | 1119 bp |
| Locus ID | 11274 |
| UniProt ID | Q9UMW8 |
| Domains | UCH |
| Protein Families | Druggable Genome, Protease |
| Gene Summary | The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. [provided by RefSeq, Sep 2011] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202374 | USP18 (Myc-DDK-tagged)-Human ubiquitin specific peptidase 18 (USP18) |
CNY 3656.00 |
|
| RC202374L1 | Lenti ORF clone of Human ubiquitin specific peptidase 18 (USP18), Myc-DDK-tagged |
CNY 6056.00 |
|
| RC202374L2 | Lenti ORF clone of Human ubiquitin specific peptidase 18 (USP18), mGFP tagged |
CNY 6056.00 |
|
| RC202374L3 | Lenti ORF clone of Human ubiquitin specific peptidase 18 (USP18), Myc-DDK-tagged |
CNY 6056.00 |
|
| RC202374L4 | Lenti ORF clone of Human ubiquitin specific peptidase 18 (USP18), mGFP tagged |
CNY 6056.00 |
|
| RG202374 | USP18 (tGFP-tagged) - Human ubiquitin specific peptidase 18 (USP18) |
CNY 5256.00 |
