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GSK3 alpha (GSK3A) (NM_019884) Human Untagged Clone
CAT＃: SC112599
GSK3A (untagged)-Human glycogen synthase kinase 3 alpha (GSK3A)
CNY 2,950.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_019884 edited
ATGAGCGGCGGCGGGCCTTCGGGAGGCGGCCCTGGGGGCTCGGGCAGGGCGCGGACTAGC TCGTTCGCGGAGCCCGGCGGCGGAGGCGGAGGAGGCGGCGGCGGCCCCGGAGGCTCGGCC TCCGGCCCAGGCGGCACCGGCGGCGGAAAGGCATCTGTCGGGGCCATGGGTGGGGGCGTC GGGGCCTCGAGCTCCGGGGGTGGACCCGGCGGCAGCGGCGGAGGAGGCAGCGGAGGCCCC GGCGCAGGCACTAGCTTCCCGCCGCCCGGGGTGAAGCTGGGCCGTGACAGCGGGAAGGTG ACCACAGTCGTAGCCACTCTAGGCCAAGGCCCAGAGCGCTCCCAAGAAGTGGCTTACACG GACATCAAAGTGATTGGCAATGGCTCATTTGGGGTCGTGTACCAGGCACGGCTGGCAGAG ACCAGGGAACTAGTCGCCATCAAGAAGGTTCTCCAGGACAAGAGGTTCAAGAACCGAGAG CTGCAGATCATGCGTAAGCTGGACCACTGCAATATTGTGAGGCTGAGATACTTTTTCTAC TCCAGTGGCGAGAAGAAAGACGAGCTTTACCTAAATCTGGTGCTGGAATATGTGCCCGAG ACAGTGTACCGGGTGGCCCGCCACTTCACCAAGGCCAAGTTGACCATCCCTATCCTCTAT GTCAAGGTGTACATGTACCAGCTCTTCCGCAGCTTGGCCTACATCCACTCCCAGGGCGTG TGTCACCGCGACATCAAGCCCCAGAACCTGCTGGTGGACCCTGACACTGCTGTCCTCAAG CTCTGCGATTTTGGCAGTGCAAAGCAGTTGGTCCGAGGGGAGCCCAATGTCTCCTACATC TGTTCTCGCTACTACCGGGCCCCAGAGCTCATCTTTGGAGCCACTGATTACACCTCATCC ATCGATGTTTGGTCAGCTGGCTGTGTACTGGCAGAGCTCCTCTTGGGCCAGCCCATCTTC CCTGGGGACAGTGGGGTGGACCAGCTGGTGGAGATCATCAAGGTGCTGGGAACACCAACC CGGGAACAAATCCGAGAGATGAACCCCAACTACACGGAGTTCAAGTTCCCTCAGATTAAA GCTCACCCCTGGACAAAGGTGTTCAAATCTCGAACGCCGCCAGAGGCCATCGCGCTCTGC TCTAGCCTGCTGGAGTACACCCCATCCTCAAGGCTCTCCCCACTAGAGGCCTGTGCGCAC AGCTTCTTTGATGAACTGCGATGTCTGGGAACCCAGCTGCCTAACAACCGCCCACTTCCC CCTCTCTTCAACTTCAGTGCTGGTGAACTCTCCATCCAACCGTCTCTCAACGCCATTCTC ATCCCTCCTCACTTGAGGTCCCCAGCGGGCACTACCACCCTCACCCCGTCCTCACAAGCT TTAACTGAGACTCCGACCAGCTCAGACTGGCAGTCGACCGATGCCACACCTACCCTCACT AACTCCTCCTGA >OriGene 5' read for NM_019884 unedited
ACACGCAATTCGCACGAGGCCGGAGCCCAAGCCAGAGCGGCGCGGCCTGGAAGAGGCCAG GGCCCGGGGGAGGCGGCGGCAGCGGCGGCGGCTGGGGCAGCCCGGGCAGCCCGAGCCCCG CAGCCTGGGCCTGTGCTCGGCGCCATGAGCGGCGGCGGGCCTTCGGGAGGCGGCCCTGGG GGCTCGGGCAGGGCGCGGACTAGCTCGTTCGCGGAGCCCGGCGGCGGAGGCGGAGGAGGC GGCGGCGGCCCCGGAGGCTCGGCCTCCGGCCCAGGCGGCACCGGCGGCGGAAAGGCATCT GTCGGGGCCATGGGTGGGGGCGTCGGGGCCTCGAGCTCCGGGGGTGGACCCGGCGGCAGC GGCGGAGGAGGCAGCGGAGGCCCCGGCGCAGGCACTAGCTTCCCGCCGCCCGGGGTGAAG CTGGGCCGTGACAGCGGGAAGGTGACCACAGTCGTAGCCACTCTAGGCCAAGGCCCAGAG CGCTCCCAAGAAGTGGCTTACACGGACATCAAAGTGATTGGCAATGGCTCATTTGGGGTC GTGTACCAGGCACGGCTGGCAGAGACCAGGGAACTAGTCGCCATCAAGAAGGTTCTCCAG GACAAGAGGTTCAAGAACCGAGAGCTGCAGATCATGCGTAAGCTGGACCACTGCAATATT GTGAGGCTGAGATACTTTTTCTACTCCAGTGGCGAGAAGAAAGACGAGCTTTACCTAAAT CTGGTGCTGGAATATGTGCCCGAGACAGTGTACCCGGGTGGCCCGCCACTTCACCAAGGC CAAGTTGACCATCCCTATCCTCTATGTCAAGGTGTACATGTACCAGCTCTTCCGCAGCTT GGCCTACATNCACTCCNAGGGCGTGTG >OriGene 3' genomic read for NM_019884 unedited
TTTTTTTTTTTTTTTTTCATGCCAATAATTTATTGAACGGAGGTCTGTACACAGGCAAAC CTTACTGTGGAAACTAAGACATCAGGAGCTCTCTCCACTCCCCTGGCCCTCCAGGGTGGG GTGAGGAGGGAGTAAACCTTGGGGGCAGAGGACAGGAGGGGAGTTACAGCTGTAGGAGGG GCGGGGCCAGGTTGGACGGTGCGAATCGACGTTTTCTTTAAGAAAAAAATTATAACAATC TATTTACACCCGGGGGCCAGGGAAGGGAAAAGGAGACGGGCTGGGCTGGTTCTATTTACA AGGGACACAGGAGGGGAGGGGGTCTGGAGGAGGTGGAGGTCTGGGGGAGGGGAGGCCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_019884 |
| Insert Size | 2170 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_019884.2, NP_063937.2 |
| RefSeq Size | 2200 bp |
| RefSeq ORF | 1452 bp |
| Locus ID | 2931 |
| UniProt ID | P49840 |
| Domains | pkinase, TyrKc, S_TKc |
| Protein Families | Druggable Genome, Protein Kinase |
| Protein Pathways | Chemokine signaling pathway |
| Gene Summary | This gene encodes a multifunctional Ser/Thr protein kinase that is implicated in the control of several regulatory proteins including glycogen synthase, and transcription factors, such as JUN. It also plays a role in the WNT and PI3K signaling pathways, as well as regulates the production of beta-amyloid peptides associated with Alzheimer's disease. [provided by RefSeq, Oct 2011] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
A Noncatalytic Domain of Glycogen Synthase Kinase-3 (GSK-3) Is Essential for Activity
,Jessica L. Buescher and Christopher J. Phiel,
J. Biol. Chem., Mar 2010; 285: 7957 - 7963
[GSK3A]
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