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TANK (NM_133484) Human Untagged Clone
CAT＃: SC110107
TANK (untagged)-Human TRAF family member-associated NFKB activator (TANK), transcript variant 2
CNY 3,990.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | I-TRAF; ITRAF; TRAF2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_133484, the custom clone sequence may differ by one or more nucleotides
ATGGATAAAAACATTGGCGAGCAACTCAATAAAGCGTATGAAGCCTTCCGGCAGGCATGCATGGATAGAG ATTCTGCAGTAAAAGAATTACAGCAAAAGACTGAGAACTATGAGCAGAGAATACGTGAACAACAGGAACA GCTGTCACTTCAACAGACTATTATTGACAAGCTAAAATCTCAGTTACTTCTTGTGAATTCCACTCAAGAT AACAATTATGGCTGTGTTCCTCTGCTTGAAGACAGTGAAACAAGAAAGAATAATTTGACTCTTGATCAGC CACAAGATAAAGTGATTTCAGGAATAGCAAGAGAAAAACTACCAAAGGTAGACATTGCTTCTGCAGAAAG CAGCATTTAA >OriGene 5' read for NM_133484 unedited
TCCCATTTTGTAATACGACTCACTATTAGGGCGGCCGCGATTCGGCACCAGGNACAGTTT AAGCAGCATTGTTAGAGCCTGTGGGAAAACACTTTACAACTGTGTAACTGTCTTCATCTT TACAGAGGAATAGTCTACAAAGGAAGACTTGTAACCTGGAGAAGAGACCTGTCATTTACT CCATCCTTTATAGTGATGCTACAGGACGAAGAGGAATGGATAAAAACATTGGCGAGCAAC TCAATAAAGCGTATGAAGCCTTCCGGCAGGCATGCATGGATAGAGATTCTGCAGTAAAAG AATTACAGCAAAAGACTGAGAACTATGAGCAGAGAATACGTGAACAACAGGAACAGCTGT CACTTCAACAGACTATTATTGACAAGCTAAAATCTCAGTTACTTCTTGTGAATTCCACTC AAGATAACAATTATGGCTGTGTTCCTCTGCTTGAAGACAGTGAAACAAGAAAGAATAATT TGACTCTTGATCAGCCACAAGATAAAGTGATTTCAGGAATAGCAAGAGAAAAACTACCAA AGGTAAGAAGACAAGAGGTTTCTTCTNCTAGAAAAGAACTTCAGAAGGAGTCTTGGCAGT CCTTTGCTCCATGAAAGGGGTAATATAGAGAAGACTTTCTGGGATCTGAAAGAAGATTTC ATAAAATATGCATGCTAGCANAAGCACAGAAAGACCACTTNAGCAAACTTTATATACCAG ACACTGCAACTGAAACACAGTGCTCTGTGCCTATACAGTGTACGGATNAAACAGATAAAC AAGAAAGCGCTGTTAAGCCTCAGCTAAAGATGATATAATAGAGGTGCACATTCACACATC TGTACACCAGAAGACTGTGCNAGATAAGGAGAACCTCCTTTGAATACTTTCTAAATCATG TCAGTTTCCACTATGGACATGACTCACTTTTTACTANCACTCAGAAGACCGCACCTTATT CTGCAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_133484 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_133484.1, NP_597841.1 |
| RefSeq Size | 698 bp |
| RefSeq ORF | 360 bp |
| Locus ID | 10010 |
| UniProt ID | Q92844 |
| Protein Families | Druggable Genome |
| Protein Pathways | RIG-I-like receptor signaling pathway |
| Gene Summary | The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (2) lacks multiple exons from the 3' end and contains an alternate 3' segment compared to variant 1. The resulting isoform (b) has a shorter and distinct C-terminus, as compared to isoform (a). |
Documents
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| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215997 | TANK (Myc-DDK-tagged)-Human TRAF family member-associated NFKB activator (TANK), transcript variant 2 |
CNY 3,990.00 |
|
| RC215997L3 | Lenti-ORF clone of TANK (Myc-DDK-tagged)-Human TRAF family member-associated NFKB activator (TANK), transcript variant 2 |
CNY 5,890.00 |
|
| RC215997L4 | Lenti-ORF clone of TANK (mGFP-tagged)-Human TRAF family member-associated NFKB activator (TANK), transcript variant 2 |
CNY 5,890.00 |
|
| RG215997 | TANK (tGFP-tagged) - Human TRAF family member-associated NFKB activator (TANK), transcript variant 2 |
CNY 4,370.00 |
