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UNG (NM_003362) Human Untagged Clone
CAT＃: SC109874
UNG (untagged)-Human uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1
CNY 2,400.00
CNY 6,270.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DGU; HIGM4; HIGM5; UDG; UNG1; UNG2; UNG15 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_003362, the custom clone sequence may differ by one or more nucleotides
ATGGGCGTCTTCTGCCTTGGGCCGTGGGGGTTGGGCCGGAAGCTGCGGACGCCTGGGAAGGGGCCGCTGC AGCTCTTGAGCCGCCTCTGCGGGGACCACTTGCAGGCCATCCCAGCCAAGAAGGCCCCGGCTGGGCAGGA GGAGCCTGGGACGCCGCCCTCCTCGCCGCTGAGTGCCGAGCAGTTGGACCGGATCCAGAGGAACAAGGCC GCGGCCCTGCTCAGACTCGCGGCCCGCAACGTGCCCGTGGGCTTTGGAGAGAGCTGGAAGAAGCACCTCA GCGGGGAGTTCGGGAAACCGTATTTTATCAAGCTAATGGGATTTGTTGCAGAAGAAAGAAAGCATTACAC TGTTTATCCACCCCCACACCAAGTCTTCACCTGGACCCAGATGTGTGACATAAAAGATGTGAAGGTTGTC ATCCTGGGACAGGATCCATATCATGGACCTAATCAAGCTCACGGGCTCTGCTTTAGTGTTCAAAGGCCTG TTCCGCCTCCGCCCAGTTTGGAGAACATTTATAAAGAGTTGTCTACAGACATAGAGGATTTTGTTCATCC TGGCCATGGAGATTTATCTGGGTGGGCCAAGCAAGGTGTTCTCCTTCTCAACGCTGTCCTCACGGTTCGT GCCCATCAAGCCAACTCTCATAAGGAGCGAGGCTGGGAGCAGTTCACTGATGCAGTTGTGTCCTGGCTAA ATCAGAACTCGAATGGCCTTGTTTTCTTGCTCTGGGGCTCTTATGCTCAGAAGAAGGGCAGTGCCATTGA TAGGAAGCGGCACCATGTACTACAGACGGCTCATCCCTCCCCTTTGTCAGTGTATAGAGGGTTCTTTGGA TGTAGACACTTTTCAAAGACCAATGAGCTGCTGCAGAAGTCTGGCAAGAAGCCCATTGACTGGAAGGAGC TGTGA >OriGene 5' read for NM_003362 unedited
GGGTCAAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGTCACCGCG ACGCTCCTCGGGNAAGCCATAGGGCGCCTCCCAGCCCGTCTCCCCGCTCCAGTTTAGAAC CTAATTCCCAATTCCCGGAAGCTGCGGACGCCTGGGAAGGGGCCGCTGCAGCTCTTGAGC CGCCTCTGCGGGGACCACTTGCAGGCCATCCCAGCCAAGAAGGCCCCGGCTGGGCAGGAG GAGCCTGGGACGCCGCCCTCCTCGCCGCTGAGTGCCGAGCAGTTGGACCGGATCCAGAGG AACAAGGCCGCGGCCCTGCTCAGACTCGCGGCCCGCAACGTGCCCGTAGGCTTTGGAGAG AGCTGGAAGAAGCACCTCAGCGGGGAGTTCGAGAAACCGTATTTTATCAAGCTAATGGGA TTTGTTGCAGAAGAAAGAAAGCATTACACTGTTTATCCACCCCCACACCAAGTCTTCACC TGGACCCAGATGTGTGACATAAAAGATGTGAAGGTTGTCATCCTGGGACAGGATCCATAT CATGGACCTAATCAAGCTCACGGGCTCTGCTTTAGTGTTCAAAGGCCTGTTCCGCCTCCG CCCAGTTTGGAGAACATTTATAAAGAGTTGTCTACAGACATAGAGGATTTTGTTCATCCT GGCCATGGAGATTTATCTGGGTGGGCCAAGCAAGGTGTTCTCCTTCTCAACGCTGTCCTC ACGGTTCGTGCCCATCAAGCCAACTCTCATAAGGAGCGAGGCTGGGAGCAGTTCACTGAT GCAGTTGTGTCCTGGCTAAATCAGAACTCGAATGGGCCTNNGTTTTCTGCTCTGGGGCTC TTATGCTCAGAAGAAGGCAGTGCCATTGATAGGAAGCGGCACCATGTACTACAGACGGNT CATCCCTCCTTNTN >OriGene 3' read for NM_003362 unedited
NNNNTATCTCTGNAACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTA ACTTTTAACAAACTTTTATTAACAAACCTCGCGTAGAGCCAACTCTAACCCGACTAACAG CAAAAACAGCATTGCTAACAAGATCAAGGATGGAGGTGCAGACCCAATAAAGACCGTCTC TTAAAAAAAGGACTGGGAAAAATATATATATATATATCTGCATGAGTACTTCTTAAAAAA CTAAAACTTTCCAGTGTTGCAGGAAAAAATATCCCAAAGTGATTTCAGTCGGTTAAAAAA AACAGTACTTGGCAGTCTGTGCTGCCTTAAAAACCCCAACTGGACATAACCCTAGGAGAA AATCACCCCACCCCATAAAGACAAAATTCCCTTTTCTCCTCTTCCTTGTTCAAATTCCAC TGCTTATTCCACCAACACCCAAGGAATAACAAGACCCAGCTTACTTCTCTCGGTCTCTTA TCTGATAAAGCTCACAGCAATCTTAACCTCTACTACAATCAGGAAATTGAGCCCTAATTT CTGGGCCAGATTCTGGAAAGTTGCAAAACATCCTTATGCTGCGAGGGGCCTGAGGACTCC TTCAAAGATCAAGGGGGCAGTGGAACTGGCAGAGACTGGCATGCCTGCCCTGCCAGGCTG AGACAAGGGGACCTTTCTAAGCAAAACACCCCCACATCTGTCACTGAAAGTCTAACCAGG CAAAACCAAGGAGCAACAGGCGCCCAAACTAGGCTGTGCCTGAAAAGTGCACATCTCCCC TGTTTCACCATAAAGGCGAGGGAAAAAAAAGAGCCAACTGAGTATTTGACCTCATTTGTC CTCTGCATAATTTAAGCCGAAACCATGTTGCAGAAAAAGACATTGGTCCAAAGGCACCCC TTTGTGGTNTGGGGGTGGAAACACTCGGCATTCN |
| Restriction Sites | ECoRI-NOT |
| ACCN | NM_003362 |
| Insert Size | 915 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003362.2, NP_003353.1 |
| RefSeq Size | 2081 bp |
| RefSeq ORF | 915 bp |
| Locus ID | 7374 |
| UniProt ID | P13051 |
| Domains | UDG |
| Protein Families | Druggable Genome, Stem cell - Pluripotency |
| Protein Pathways | Base excision repair, Primary immunodeficiency |
| Gene Summary | This gene encodes one of several uracil-DNA glycosylases. One important function of uracil-DNA glycosylases is to prevent mutagenesis by eliminating uracil from DNA molecules by cleaving the N-glycosylic bond and initiating the base-excision repair (BER) pathway. Uracil bases occur from cytosine deamination or misincorporation of dUMP residues. Alternative promoter usage and splicing of this gene leads to two different isoforms: the mitochondrial UNG1 and the nuclear UNG2. The UNG2 term was used as a previous symbol for the CCNO gene (GeneID 10309), which has been confused with this gene, in the literature and some databases. [provided by RefSeq, Nov 2010] Transcript Variant: This variant (1) uses the downstream promoter and a full-length exon 1B. It encodes the UNG1 isoform, which includes a mitochondrial targeting sequence. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Monitoring eukaryotic and bacterial UDG repair activity with DNA-multifluorophore sensors
,Toshikazu Ono, Sarah K. Edwards, Shenliang Wang, Wei Jiang, and Eric T. Kool,
Nucleic Acids Res., Jul 2013; 41: e127.
,PubMed ID 23644286
[UNG]
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Resources
Other Versions
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| RC208667 | UNG (Myc-DDK-tagged)-Human uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1 |
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| RC208667L3 | Lenti ORF clone of Human uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1, Myc-DDK-tagged |
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| RC208667L4 | Lenti ORF clone of Human uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1, mGFP tagged |
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| RG208667 | UNG (tGFP-tagged) - Human uracil-DNA glycosylase (UNG), nuclear gene encoding mitochondrial protein, transcript variant 1 |
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