GPS2 (NM_004489) Human Untagged Clone
CAT＃: SC109278
GPS2 (untagged)-Human G protein pathway suppressor 2 (GPS2)
CNY 2400.00
CNY 6270.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | AMF-1 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC109278 sequence for NM_004489 edited (data generated by NextGen Sequencing)
ATGCCCGCACTCCTGGAGCGCCCCAAGCTTTCCAACGCCATGGCCAGGGCGCTGCACCGG CACATTATGATGGAGCGGGAGCGCAAGCGGCAGGAGGAAGAAGAGGTGGATAAGATGATG GAACAGAAGATGAAGGAAGAACAGGAGAGAAGGAAGAAAAAGGAGATGGAAGAGAGAATG TCATTAGAGGAGACCAAGGAACAAATTCTGAAGTTGGAGGAGAAGCTTTTGGCTCTACAG GAAGAGAAGCACCAGCTTTTCCTGCAGCTCAAGAAAGTTTTACATGAGGAAGAAAAACGG AGGCGAAAGGAACAGAGTGACCTGACCACCCTGACATCAGCTGCATACCAGCAGAGCCTG ACTGTTCACACAGGAACTCATCTCCTCAGCATGCAGGGGAGCCCTGGAGGACACAATCGC CCAGGCACCCTCATGGCAGCTGACAGAGCCAAACAAATGTTTGGACCCCAAGTGCTTACG ACCCGGCACTACGTGGGCTCAGCAGCTGCTTTTGCAGGGACACCAGAGCATGGACAATTC CAAGGCAGTCCTGGTGGTGCCTATGGGACTGCTCAGCCCCCACCTCACTATGGGCCCACA CAGCCAGCTTATAGTCCTAGTCAGCAGCTCAGAGCTCCTTCGGCATTCCCTGCAGTGCAG TACCTATCTCAGCCACAGCCACAGCCCTATGCTGTGCATGGCCACTTTCAGCCCACTCAG ACAGGTTTCCTCCAGCCTGGTGGTGCCCTGTCCTTGCAAAAGCAGATGGAACATGCTAAC CAGCAGACTGGCTTCTCCGACTCATCCTCTCTGCGCCCCATGCACCCCCAGGCTCTGCAT CCAGCCCCTGGACTCCTTGCTTCCCCCCAGCTCCCTGTGCAGATGCAGCCAGCAGGAAAG TCGGGCTTTGCAGCTACCAGCCAACCTGGCCCTCGGCTCCCCTTCATCCAACACAGCCAG AACCCGCGATTCTACCACAAGTGA Clone variation with respect to NM_004489.4 333 a=>g >OriGene 5' read for NM_004489 unedited
NGGGTCGAATTTGTATACGACTCATATNAGGCGGCCGCGCGTCGGNACCGCTGAGAAGCG CANAGAAGCGGGCCCCGTCTGAGGTCTGGCAGTCAGAGACAGCCGGGCGCCCACGGCCCG AGCGCCCACGGCAGCACCATGCCCGCACTCCTGGAGCGCCCCAAGCTTTCCAACGCCATG GCCAGGGCGCTGCACCGGCACATTATGATGGAGCGGGAGCGCAAGCGGCAGGAGGAAGAA GAGGTGGATAAGATGATGGAACAGAAGATGAAGGAAGAACAGGAGAGAAGGAAGAAAAAG GAGATGGAAGAGAGAATGTCATTAGAGGAGACCAAGGAACAAATTCTGAAGTTGGAGGAG AAGCTTTTGGCTCTACAGGAAGAGAAGCACCAGCTTTTCCTGCAGCTCAAGAAAGTTTTA CATGAGGAAGAAAAACGGAGGCGAAAGGAACAGAGTGACCTGACCACCCTGACATCAGCT GCATACCAGCAGAGCCTGACTGTTCACACAGGAACTCATCTCCTCAGCATGCAGGGGAGC CCTGGAGGACACAATCGCCCAGGCACCCTCATGGCAGCTGACAGAGCCAAACAAATGTTT GGACCCCAAGTGCTTACGACCCGGCACTACGTGGGCTCAGCAGCTGCTTTTGCAGGGACA CCAGAGCATGGACAATTCCAAGGCAGTCCTGGTGGTGCCTATGGGACTGCTCAGCCCCAC CTCACTATGGGCCCACACAGNNCAGCTATAGTCCTAGTCAGCAGCTCAGAGCTCCTTCGG CATTCCCTGCAGTGCAGTACCTATCTCAGCCACACCACAGCCCTATGCTGTGCATGGGCA CTTTCAGCCACTCAAACAGGNTTNCTCCAGNCTGGTGGGGCCCTGTCCCTGCAAAAGCAG ATGGN >OriGene 3' read for NM_004489 unedited
TCGGGGTTGCTATTTCATTGGCTCTGGGNACACACAGGGGNATACCCTCACCCACGAGGG GTGGGGGGTGTGGTGTTGAAGATATAATCTGATGGTCACTTGTGGTAGAATCGCGGGTTC TGGCTGTGTTGGATGAAGGGGAGCCGAGGGCCAGGTTGGCTGGTAGCTGCAAAGCCCGAC TTTCCTGCTGGCTGCATCTGCACAGGGAGCTGGGGGGAAGCAAGGAGTCCAGGGGCTGGA TGCAGAGCCTGGGGGTGCATGGGGCGCAGAGAGGATGAGTCGGAGAAGCCAGTCTGCTGG TTAGCATGTTCCATCTGCTTTTGCAAGGACAGGGCACCACCAGGCTGGAGGAAACCTGTC TGAGTGGGCTGAAAGTGGCCATGCACAGCATAGGGCTGTGGCTGTGGCTGAGATAGGTAC TGCACTGCAGGGAATGCCGAAGGAGCTCTGAGCTGCTGACTAGGACTATAAGCTGGCTGT GTGGGCCCATAGTGAGGTGGGGGCTGAGCAGTCCCATAGGCACCACCAGGACTGCCTTGG AATTGTCCATGCTCTGGTGTCCCTGCAAAAGCAGCTGCTGAGCCCACGTAGTGCCGGGTC GTAAGCACTTGGGGTCCAAACATTTGTTTGGCTCTGTCAGCTGCCATGAGGGTGCCTGGG CGATTGTGTCCTCCAGGGCTCCCCTGCATGCTGAGGAGATGAGTTCCTGTGTGAACAGTC AGGCTCTGCTGGTATGCAGCTGATGTCAGGGTGGTCANGTCACTCTGTTCCTTTCGCCTT CGTTTTTCCTCCTCATGTAAAACTTTCTTGAGCTGCAGGAAAAACTGGTGCTTCTCTTCC TGTAAAGCCAAAAGCTNCTCTCCACCTCCAGAAATTGTCCCTGGTCTCCTCTATGACATT CTCTTCTCCATCCCCCTTTNTTNCCTCCTCTCCGGGNCTTCCTNCATACTTTGTNCCATC ATCTTATCCACCTTTNCTTCCTCCTGCCGGTTGCGCTCG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004489 |
| Insert Size | 1300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004489.4, NP_004480.1 |
| RefSeq Size | 1181 bp |
| RefSeq ORF | 984 bp |
| Locus ID | 2874 |
| UniProt ID | Q13227 |
| Domains | NEUZ |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) shares several exons with variant 1 and encodes G protein pathway suppressor 2, a distinct downstream protein. Variants 2 and 3 differ in their 5' UTR and specify the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210464 | GPS2 (Myc-DDK-tagged)-Human G protein pathway suppressor 2 (GPS2) |
CNY 2400.00 |
|
| RC210464L1 | Lenti ORF clone of Human G protein pathway suppressor 2 (GPS2), Myc-DDK-tagged |
CNY 4800.00 |
|
| RC210464L2 | Lenti ORF clone of Human G protein pathway suppressor 2 (GPS2), mGFP tagged |
CNY 5890.00 |
|
| RC210464L3 | Lenti ORF clone of Human G protein pathway suppressor 2 (GPS2), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC210464L4 | Lenti ORF clone of Human G protein pathway suppressor 2 (GPS2), mGFP tagged |
CNY 5890.00 |
|
| RG210464 | GPS2 (tGFP-tagged) - Human G protein pathway suppressor 2 (GPS2) |
CNY 4000.00 |
