SLC7A6 (NM_003983) Human Untagged Clone
CAT＃: SC108459
SLC7A6 (untagged)-Human solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), transcript variant 1
CNY 3840.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LAT-2; LAT3; y+LAT-2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108459 sequence for NM_003983 edited (data generated by NextGen Sequencing)
ATGGAAGCCAGGGAGCCTGGGAGGCCCACACCCACCTACCATCTTGTCCCTAACACCAGC CAGTCCCAGGTGGAAGAAGATGTCAGCTCGCCACCTCAAAGGTCCTCCGAAACTATGCAG CTGAAGAAGGAGATCTCCCTGCTGAATGGGGTCAGCCTGGTGGTGGGCAACATGATCGGC TCAGGGATCTTTGTCTCACCCAAGGGTGTGCTGGTACACACTGCCTCCTATGGGATGTCA CTGATTGTGTGGGCCATTGGTGGGCTCTTCTCTGTTGTGGGTGCCCTTTGTTATGCAGAG CTGGGGACCACCATCACCAAGTCGGGAGCCAGCTACGCTTATATTCTAGAGGCCTTTGGG GGCTTCATTGCCTTCATCCGCCTGTGGGTCTCACTGCTAGTTGTTGAGCCCACCGGTCAG GCCATCATCGCCATCACCTTTGCCAACTACATCATCCAGCCGTCCTTCCCCAGCTGTGAT CCCCCATACCTGGCCTGCCGTCTCCTGGCTGCTGCTTGCATATGTCTGCTGACATTTGTG AACTGTGCCTATGTCAAGTGGGGCACACGTGTGCAGGACACGTTCACTTACGCCAAGGTC GTAGCGCTCATTGCCATCATTGTCATGGGCCTTGTTAAACTGTGCCAGGGACACTCTGAG CACTTTCAGGACGCCTTTGAGGGTTCCTCCTGGGACATGGGAAACCTCTCTCTTGCCCTC TACTCTGCCCTCTTCTCTTACTCAGGTTGGGACACCCTTAATTTTGTAACAGAAGAAATC AAAAACCCAGAAAGAAATTTGCCCTTGGCCATTGGGATTTCTATGCCAATTGTGACGCTC ATCTACATCCTGACCAATGTGGCCTATTACACAGTGCTGAACATTTCAGATGTCCTTAGC AGTGATGCTGTGGCTGTGACATTTGCTGACCAGACGTTTGGCATGTTCAGCTGGACCATC CCCATTGCTGTTGCCCTGTCCTGCTTTGGGGGCCTCAATGCATCCATCTTTGCTTCATCA AGGTTGTTCTTCGTGGGCTCCCGGGAGGGCCACCTACCGGACCTTCTGTCCATGATCCAC ATTGAGCGTTTTACACCTATCCCTGCTTTACTGTTCAATTGCACCATGGCACTCATCTAC CTCATCGTGGAGGATGTTTTCCAGCTTATCAACTACTTCAGCTTCAGCTACTGGTTCTTC GTGGGCCTGTCTGTTGTTGGACAGCTCTACCTCCGCTGGAAGGAGCCCAAGCGGCCCCGG CCTCTCAAGCTGAGCGTGTTTTTCCCCATCGTGTTCTGCATATGCTCCGTGTTTCTGGTG ATAGTGCCCCTCTTCACTGACACCATTAATTCCCTCATTGGCATCGGGATTGCCCTTTCT GGAGTCCCTTTCTACTTCATGGGTGTTTACCTGCCAGAGTCCCGGAGGCCATTGTTTATT CGGAATGTCCTGGCTGCTATCACCAGAGGCACCCAGCAGCTTTGCTTTTGTGTCCTGACT GAGCTTGATGTAGCCGAAGAAAAAAAGGATGAGAGGAAAACTGACTAG Clone variation with respect to NM_003983.5 >OriGene 5' read for NM_003983 unedited
ATACACTCACTATAGGCGGCCGCGNAATTCGCACGAGGTGTGGCCGAGGCAGACAAGTGG AATTAGGCCTTGCTGCAGGGGACTTCATTTCCTTCTCAGTACTGGACCCATTTATGAGGA GGTGGCTTATGAAAGTGTGATGTTCGCGTATTTCTTGACAGGCCACAGCAAACACAGGTG TGCAGGAACCGTTTGTCATGGAAGCCAGGGAGCCTGGGAGGCCCACACCCACCTACCATC TTGTCCCTAACACCAGCCAGTCCCAGGTGGAAGAAGATGTCAGCTCGCCACCTCAAAGGT CCTCCGAAACTATGCAGCTGAAGAAGGAGATCTCCCTGCTGAATGGGGTCAGCCTGGTGG TGGGCAACATGATCGGCTCAGGGATCTTTGTCTCACCCAAGGGTGTGCTGGTACACACTG CCTCCTATGGGATGTCACTGATTGTGTGGGCCATTGGTGGGCTCTTCTCTGTTGTGGGTG CCCTTTGTTATGCAGAGCTGGGGACCACCATCACCAAGTCGGGAGCCAGCTACGCTTATA TTCTAGAGGCCTTTGGGGGCTTCATTGCCTTCATCCGCCTGTGGGTCTCACTGCTAGTTG TTGAGCCCACCGGTCAGGCCATCATCGCCATCACCTTTGCCAACTACATCATCCAGCCGT CCTTCCCCAGCTGTGATCCCCCATACCTGGCCTGCCGTCTNCTGGCTGCTGCTTGCATAT GTCTGCTGACATTTGTGAACTGTGCCTATGTCAAGTGGGGCACACGTGTGCAGAACACGT TCACTTACCCCAAAGGCGNAGCGCTCATTGCCATCATTGTCATTGGCCTTGTTAAACTGT GCCAGGGCACTCTGACACTTTAGGACCCCTTTGAGAGGTTCTCTGGGACTGGGAAACTCT CTTTTGCCTTTACTTGCCTCTTTTTTAATAAGGTTGGAACCCTTTATTTTGTACAAAGAA TCAAACCCGAAGAATT >OriGene 3' read for NM_003983 unedited
CCGGTCAAGAGANAATTCATTGGCTGGTTTTTTNAACAGNGNAATGCAATCAAACAATTG CATATTCTTTTGGGGAGGTTTGTCAATAACACGTTAGAAGGGAGAAGGTACAAAAATATT TACAATATGGGGGCAACTCTTACAACAACAAAAAATCCTATACGGAGGGGAGAAGTGACA AAATACTCCACGGAGGGGAGAAGTGACAAAATACTCCAGTGTGAAGGAACTTGGTTTAGA TGATAGGAAAGTGATGGCTTGTTTAAAAAAAAAAGAATTCTATATTCTTTTTTATTTATT GAGCAAGGATTTTGCATTACAATCGGGAACAAAAACAGACCTTTCTGANAAGAGAAGGGG CTCCTGCAGTAGCCTAGGAAAATCACATTTAGAATCCACTCCCGGGATGTCATTCTAGGC TCTGCTGACTACAACANCCTGAGTGAGGAGGAAAGAGGCAGCANCAGACAGCGGATGTGG AGCAAGTACCCTCTGGATGTGCAAAAGGAGTTCGGCTATGACAGCCCCCACGACCTGNAT TCAGACTGATGGTCTTGTGATGTCCATGAGGTTCTGCCACATGCCCTTGAGGGCTCTGAG TCCAAGGATAACTGCCCTGCTGACATGCTGCTAGGTTNNNCACCTCACATGNGGNNGGNA AAGCATTCAAACATATNGGCGGAATCATCCCACCACCGGNAAAACTTATGTTACGGGAGN NNGGCNNNTGNNTTNACATATTAACCCTTTTGCCTNAATTAAGGNNNNCCTACACTTTGA TTGGAAATAANCNCTTCTNNNNNNAGGGCTATTTANNNTNAAGCTTCTCTGCCAAAATNN NNNCCTGAAATAGACTCCNCGCTGTCCCCCATGNGNNNNNGGAGGACGCAAACCACTAAT AAAAAGATGNNNNGNNNGNNNNCNNNNGGNNGCCGCGTATTTGNATCTGTTCTTTTTCGA TCATTTATNCTTTAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_003983 |
| Insert Size | 5270 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_003983.3, NP_003974.2 |
| RefSeq Size | 6327 bp |
| RefSeq ORF | 1548 bp |
| Locus ID | 9057 |
| UniProt ID | Q92536 |
| Domains | aa_permeases |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Involved in the sodium-independent uptake of dibasic amino acids and sodium-dependent uptake of some neutral amino acids. Requires coexpression with SLC3A2/4F2hc to mediate the uptake of arginine, leucine and glutamine. Also acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Involved in the transport of L-arginine in monocytes. Reduces uptake of ornithine in retinal pigment epithelial (RPE) cells.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) lacks an alternate exon in the 5' UTR. Variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC224688 | SLC7A6 (Myc-DDK-tagged)-Human solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), transcript variant 1 |
CNY 3832.00 |
|
| RC224688L3 | Lenti ORF clone of Human solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), transcript variant 1, Myc-DDK-tagged |
CNY 5890.00 |
|
| RC224688L4 | Lenti ORF clone of Human solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), transcript variant 1, mGFP tagged |
CNY 5890.00 |
|
| RG224688 | SLC7A6 (tGFP-tagged) - Human solute carrier family 7 (cationic amino acid transporter, y+ system), member 6 (SLC7A6), transcript variant 1 |
CNY 4370.00 |
