LRWD1 (NM_152892) Human Untagged Clone
CAT＃: SC108154
LRWD1 (untagged)-Human leucine-rich repeats and WD repeat domain containing 1 (LRWD1)
CNY 4824.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CENP-33; ORCA |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC108154 sequence for NM_152892 edited (data generated by NextGen Sequencing)
ATGGGCCCCCTCTCGGCGCGGCTGCTAATGCAGCGCGGGCGCCCCAAGAGCGACCGGCTG GGGAAGATCCGGAGTCTGGACCTGTCAGGATTGGAGCTGCTTTCCGAGCACCTGGACCCC AAACTCCTGTGCCGCCTGACGCAGCTGCAGGAGCTTGACCTGTCTAACAACCACCTGGAG ACGCTGCCGGACAACCTGGGCCTGTCCCACCTGCGTGTCCTCCGCTGCGCCAACAACCAG CTGGGGGATGTTACTGCCTTGTGCCAGTTCCCCAAGCTCGAGGAACTCAGCCTGGAGGGC AACCCCTTCCTGACGGTCAATGACAACCTGAAAGTCTCCTTTCTCCTGCCCACGCTCCGT AAGGTCAATGGCAAGGATGCGTCCTCAACTTACTCTCAGGTGGAGAACCTGAATCGGGAG CTGACCAGCAGGGTCACAGCTCACTGGGAGAAGTTCATGGCCACACTGGGTCCTGAAGAG GAGGCTGAGAAGGCCCAGGCGGACTTTGTGAAGTCGGCTGTCAGGGATGTCCGCTACGGG CCCGAGTCCCTCAGCGAGTTCACCCAGTGGCGGGTGCGGATGATCTCTGAGGAGCTGGTG GCCGCCAGTAGGACCCAGGTGCAAAAGGCTAACAGCCCAGAGAAGCCCCCAGAAGCTGGA GCTGCCCACAAGCCCAGGGCCAGACTGGCGGCCTTGAAACGGCCAGACGACGTCCCACTC AGCCTCTCTCCCAGCAAGCGGGCGTGTGCCTCCCCGTCGGCCCAGGTGGAGGGCAGCCCT GTGGCAGGCTCCGATGGCAGCCAGCCTGCTGTGAAGCTGGAGCCCCTGCACTTCCTGCAG TGCCACAGCAAGAACAACAGCCCCCAGGACCTCGAGACCCAGCTGTGGGCCTGTGCCTTC GAGCCGGCCTGGGAGGAGGGGGCCACATCCCAGACCGTGGCCACGTGCGGCGGGGAGGCT GTGTGCGTAATTGATTGCCAGACGGGCATCGTGCTCCACAAGTACAAGGCACCCGGCGAG GAGTTCTTTTCTGTGGCCTGGACCGCTCTGATGGTGGTCACACAGGCTGGCCACAAGAAG CGCTGGAGTGTGCTGGCGGCTGCAGGCCTACGGGGCCTGGTCCGGCTGCTGCACGTGCGT GCCGGCTTCTGCTGCGGGGTCATCCGAGCCCACAAGAAGGCCATCGCCACCCTGTGCTTC AGCCCCGCCCACGAGACCCATCTCTTCACGGCCTCCTATGACAAGCGGATCATCCTCTGG GACATCGGGGTGCCCAACCAGGACTACGAATTCCAGGCCAGCCAGCTGCTCACACTGGAC ACCACCTCTATCCCCCTGCGCCTCTGCCCTGTCGCCTCCTGCCCGGACGCCCGCCTGCTG GCCGGCTGCGAGGGCGGCTGCTGCTGCTGGGACGTGCGGCTGGACCAGCCCCAAAAGAGG AGGGTGTGTGAAGTGGAATTCGTCTTCTCTGAGGGCTCCGAGGCATCTGGACGGAGAGTG GATGGGCTGGCATTTGTGAATGAGGACATCGTGGCCTCCAAGGGGAGCGGCCTGGGCACC ATCTGCCTGTGGAGCTGGAGGCAGACGTGGGGGGGCCGGGGCAGCCAGTCCACAGTGGCA GTGGTGGTCCTGGCGCGGCTGCAATGGTCGTCCACCGAGTTGGCCTACTTCTCGCTCAGC GCCTGCCCTGATAAGGGGATTGTGCTCTGTGGGGATGAGGAGGGCAACGTGTGGCTCTAC GACGTCAGCAACATCCTGAAGCAGCCACCCCTGCTGCCGGCAGCCCTGCAGGCCCCCACA CAGATCCTGAAGTGGCCCCAGCCCTGGGCCCTTGGCCAGGTGGTGACCAAGACCATGGTG AACACAGTGGTGGCCAATGCCTCCTTCACCTACCTCACCGCCCTGACGGACTCCAACATC GTAGCCATCTGGGGGAGGATGTAG Clone variation with respect to NM_152892.1 1614 g=>a >OriGene 5' read for NM_152892 unedited
TGGCAACATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACCAGCCGGGCTCCA GGAGACGCAGGGCGACGCCACACGCCGGGGTGGCCGACTGGGTCAGCGCGGGCTGCGCCT CCTCGCCATGGGCCCCCTCTCGGCGCGGCTGCTAATGCAGCGCGGGCGCCCCAAGAGCGA CCGGCTGGGGAAGATCCGGAGTCTGGACCTGTCAGGATTGGAGCTGCTTTCCGAGCACCT GGACCCCAAACTCCTGTGCCGCCTGACGCAGCTGCAGGAGCTTGACCTGTCTAACAACCA CCTGGAGACGCTGCCGGACAACCTGGGCCTGTCCCACCTGCGTGTCCTCCGCTGCGCCAA CAACCAGCTGGGGGATGTTACTGCCTTGTGCCAGTTCCCCAAGCTCGAGGAACTCAGCCT GGAGGGCAACCCCTTCCTGACGGTCAATGACAACCTGAAAGTCTCCTTTCTCCTGCCCAC GCTCCGTAAGGTCAATGGCAAGGATGCGTCCTCAACTTACTCTCAGGTGGAGAACCTGAA TCGGGAGCTGACCAGCAGGGTCACAGCTCACTGGGAGAAGTTCATGGCCACACTGGGTCC TGAAGAGGAGGCTGAGAAGGCCCAGGCGGACTTTGTGAAGTCGGCTGTCAGGGATGTCCG CTACGGGCCCGAGTCCCTCAGCGAGTTCACCCAGTGGCGGGTGCGGATGATCTCTGNAGA GCTGGTGGCCGNCAGTAGGACCCANGTGCAAAAGGCTAACAGCCCAGAGAAGCCCCCAGA AGCTGGAGCTGCCCACAAGCCCCAGGCCAGACTGGCGGCNCTTGAACGGNCAGACGACGT NCCACTCAGCCTCTCTCCAGCAAGCGGGCGTGTGCCTNCCCCGTCGNCCCAGTGGAGGGC ANNCNCCTGTGGCAGCTCCGATGGCAGCCC >OriGene 3' read for NM_152892 unedited
NNGGGTTTTGCTATGGAACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTT TTTTTTTCTTGTCCACAGTAGAGTTTAATAAAAATATTCACTGAAAGACCCCCCCCACCC CCATCGGCCCAAAGCTGAATAAGTTAGTTAGCTGTGTCCCTGGTCCTTTGCGATGGTGTG AGGCTACATCCTCCCCCAGATGGCTACGATGTTGGAGTCCGTCAGGGCGGTGAGGTAGGT GAAGGAGGCATTGGCCACCACTGTGTTCACCATGGTCTTGGTCACCACCTGGCCAAGGGC CCAGGGCTGGGGCCACTTTAGGATCTGTGTGGGGGCCTGCAGGGCTGCCCGCAACAGGGG TGGCTGCTTCAAGAAGTTGCTGACCTTCTAAAGCCCAACGTTTCCCCTCTCATCCCCCCA AAGCACAATCCCCTTTATCAGGCAGGCGCTGAGCGAAAAGTANGCCCACTCGGTGAACGA CATTGCAGCCGCGCCAGGACCACCACTGCCACTGTGGACTGGCTGCCCCGGCCCCCCCAC GTCTGCCTCCAGCTCCACAGGCAGATGGTGCCCAGGCCGCTCCCCTTGGAGGCCACGATG TCCTCATTCACAAATGCCAGCCCATCCACTCTCCGTCCAGATGCCTCGGAGCCCTCAGAG AAGACGAATTCCACTTCACACACCCTCCTCTTTTGGGGCTGGTCCAGCCGCACGTCCCAG CAGCAGCAGCCGCCCTCGCAGCCGGCCAGCAGGCGGGCGTCCGGGCAGGAGGCGACAGGG CAAAGGCGCAGGGGGATAGAGGTGGTGTCCAGTGTGAGCAGCTGGCTGGCCTGGAATTCG TAGTCCTGGTTGGGCACCCGATGTCCCAGAGATGATCCGCTGTCATG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_152892 |
| Insert Size | 2350 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_152892.1, NP_690852.1 |
| RefSeq Size | 2220 bp |
| RefSeq ORF | 1944 bp |
| Locus ID | 222229 |
| UniProt ID | Q9UFC0 |
| Domains | LRR, WD40 |
| Protein Families | Druggable Genome |
| Gene Summary | The protein encoded by this gene interacts with components of the origin recognition complex (ORC) and regulates the formation of the prereplicative complex. The encoded protein stabilizes the ORC and therefore aids in DNA replication. This protein is required for the G1/S phase transition of the cell cycle. In addition, the encoded protein binds to trimethylated histone H3 in heterochromatin and recruits the ORC and lysine methyltransferases, which help maintain the repressive heterochromatic state. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2015] Transcript Variant: This variant (1) encodes the longer isoform (1). |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207141 | LRWD1 (Myc-DDK-tagged)-Human leucine-rich repeats and WD repeat domain containing 1 (LRWD1) |
CNY 4816.00 |
|
| RC207141L3 | Lenti ORF clone of Human leucine-rich repeats and WD repeat domain containing 1 (LRWD1), Myc-DDK-tagged |
CNY 5890.00 |
|
| RC207141L4 | Lenti ORF clone of Human leucine-rich repeats and WD repeat domain containing 1 (LRWD1), mGFP tagged |
CNY 5890.00 |
|
| RG207141 | LRWD1 (tGFP-tagged) - Human leucine-rich repeats and WD repeat domain containing 1 (LRWD1) |
CNY 4370.00 |
