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MARK4 (NM_031417) Human Untagged Clone
CAT＃: SC107258
MARK4 (untagged)-Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2
CNY 5,048.00
| Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | MARK4L; MARK4S; MARKL1; MARKL1L; PAR-1D |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_031417, the custom clone sequence may differ by one or more nucleotides
ATGTCTTCGCGGACGGTGCTGGCCCCGGGCAACGATCGGAACTCGGACACGCATGGCACCTTGGGCAGTG GCCGCTCCTCGGACAAAGGCCCGTCCTGGTCCAGCCGCTCACTGGGTGCCCGTTGCCGGAACTCCATCGC CTCCTGTCCCGAGGAGCAGCCCCACGTGGGCAACTACCGCCTGCTGAGGACCATTGGGAAGGGCAACTTT GCCAAAGTCAAGCTGGCTCGGCACATCCTCACTGGTCGGGAGGTTGCCATCAAGATTATCGACAAAACCC AGCTGAATCCCAGCAGCCTGCAGAAGCTGTTCCGAGAAGTCCGCATCATGAAGGGCCTAAACCACCCCAA CATCGTGAAGCTCTTTGAGGTGATTGAGACTGAGAAGACGCTGTACCTGGTGATGGAGTACGCAAGTGCT GGAGAAGTGTTTGACTACCTCGTGTCGCATGGCCGCATGAAGGAGAAGGAAGCTCGAGCCAAGTTCCGAC AGATTGTTTCGGCTGTGCACTATTGTCACCAGAAAAATATTGTACACAGGGACCTGAAGGCTGAGAACCT CTTGCTGGATGCCGAGGCCAACATCAAGATTGCTGACTTTGGCTTCAGCAACGAGTTCACGCTGGGATCG AAGCTGGACACGTTCTGCGGGAGCCCCCCATATGCCGCCCCGGAGCTGTTTCAGGGCAAGAAGTACGACG GGCCGGAGGTGGACATCTGGAGCCTGGGAGTCATCCTGTACACCCTCGTCAGCGGCTCCCTGCCCTTCGA CGGGCACAACCTCAAGGAGCTGCGGGAGCGAGTACTCAGAGGGAAGTACCGGGTCCCTTTCTACATGTCA ACAGACTGTGAGAGCATCCTGCGGAGATTTTTGGTGCTGAACCCAGCTAAACGCTGTACTCTCGAGCAAA TCATGAAAGACAAATGGATCAACATCGGCTATGAGGGTGAGGAGTTGAAGCCATACACAGAGCCCGAGGA GGACTTCGGGGACACCAAGAGAATTGAGGTGATGGTGGGTATGGGCTACACACGGGAAGAAATCAAAGAG TCCTTGACCAGCCAGAAGTACAACGAAGTGACCGCCACCTACCTCCTGCTGGGCAGGAAGACTGAGGAGG GTGGGGACCGGGGCGCCCCAGGGCTGGCCCTGGCACGGGTGCGGGCGCCCAGCGACACCACCAACGGAAC AAGTTCCAGCAAAGGCACCAGCCACAGCAAAGGGCAGCGGAGTTCCTCTTCCACCTACCACCGCCAGCGC AGGCATAGCGATTTCTGTGGCCCATCCCCTGCACCCCTGCACCCCAAACGCAGCCCGACGAGCACGGGGG AGGCGGAGCTGAAGGAGGAGCGGCTGCCAGGCCGGAAGGCGAGCTGCAGCACCGCGGGGAGTGGGAGTCG AGGGCTGCCCCCCTCCAGCCCCATGGTCAGCAGCGCCCACAACCCCAACAAGGCAGAGATCCCAGAGCGG CGGAAGGACAGCACGAGCACCCCCAACAACCTCCCTCCTAGCATGATGACCCGCAGAAACACCTACGTTT GCACAGAACGCCCGGGGGCTGAGCGCCCGTCACTGTTGCCAAATGGGAAAGAAAACAGCTCAGGCACCCC ACGGGTGCCCCCTGCCTCCCCCTCCAGTCACAGCCTGGCACCCCCATCAGGGGAGCGGAGCCGCCTGGCA CGCGGTTCCACCATCCGCAGCACCTTCCATGGTGGCCAGGTCCGGGACCGGCGGGCAGGGGGTGGGGGTG GTGGGGGTGTGCAGAATGGGCCCCCTGCCTCTCCCACACTGGCCCATGAGGCTGCACCCCTGCCCGCCGG GCGGCCCCGCCCCACCACCAACCTCTTCACCAAGCTGACCTCCAAACTGACCCGAAGGGTTACCCTCGAT CCCTCTAAACGGCAGAACTCTAACCGCTGTGTTTCGGGCGCCTCTCTGCCCCAGGGATCCAAGATCAGGT CGCAGACGAACCTGAGAGAATCGGGGGACCTGAGGTCACAAGTTGCCATCTACCTTGGGATCAAACGGAA ACCGCCCCCCGGCTGCTCCGATTCCCCTGGAGTGTGA >OriGene 5' read for NM_031417 unedited
CGGTTTTCGGGCAGTGNCTGGCCCCCGGTTCAACNTNCGGNAACTCGCCACGCATGGCAC CTTGGGCAGTGGCCGCTCCTCGGNCAAAGGCCCGTCCTGGTCCAGCCGCTCACTGGGTGC CCGTTGCCGGAACTCCATCGCCTCCTGTCCCGAGGAGCAGCCCCACGTGGGCAACTACCG CCTGCTGAGGACCATTGGGAAGGGCAACTTTGCCAAAGTCAAGCTGGCTCGGCACATCCT CACTGGTCGGGAGGTTGCCATCAAGATTATCGACAAAACCCAGCTGAATCCCAGCAGCCT GCAGAAGCTGTTCCGAGAAGTCCGCATCATGAAGGGCCTAAACCACCCCAACATCGTGAA GCTCTTTGAGGTGATTGAGACTGAGAAGACGCTGTACCTGGTGATGGAGTACGCAAGTGC TGGAGAAGTGTTTGACTACCTCGTGTCGCATGGCCGCATGAAGGAGAAGGAAGCTCGAGC CAAGTTCCGACAGATTGTTTCGGCTGTGCACTATTGTCACCAGAAAAATATTGTACACAG GGACCTGAAGGCTGAGAACCTCTTGCTGGATGCCGAGGCCAACATCAAGATTGCTGACTT TGGCTTCAGCAACGAGTTCACGCTGGGATCGAAGCTGGACACGTTCTGCGGGAGCCCCCC ATATGCCGCCCCGGAGCTGTTTCAGGGCAAGAAGTACGACGGGCCGGGAGTGGACATCTG GAGCCTGGGAGTCATCCTGTACACCCTCGTCAGCGGCTCCCTGCCCTTCGACGGGCACAA CCTCAAAGAGCTGCGGGAGCGAGTACTCAGAGGGAAGTACGGGGTCCCTTTCTACATGTC AACAGACTGTGAGAGCATCCTGCGGAGAATTTTGGTGCTGAACCCAGCTAAACGCTGTAC TCTCGAGCAATCATGAAAGACAATGGAT >OriGene 3' read for NM_031417 unedited
NNAAATTACTTGNACCGCGCCGCTTTCNANNGATCGGTTTTTTTTTTTTTTTTTTTTTTT GGGGAGGGGGGGACTCTCTTAAATTATTGGGCAACAGGCTGCAGGTGAGGGGGCTGACAG GAGGAGGGTCGGGGTGTAATAACTTAAAAACCGTAGGTGACAGCGGCAGCTCCTCAAGAG ACCTTTGCAGAGGGGAGGGTGTGGGGTATTTACAAGGATTTGTACAAAGTGCCCCGCGCC AGCCTGGGGCAGGAAGTGGGGGTTTGAGCGTGAGGGGACGGGAGGGGAAGGAATCTGCCT CTCTGACCCCCACTCCCAGTCCCCCAGATTCTCCAGTCTTTAGGCTCAGCAGCTCTCCCT GCCCCTGCCCAAGGCCTAATTTTGAGCTGTTGGGAGGAATGGAAGATTTCCTCAGTTTCC CTCCCTGCCCCTGCCCTGTCCCCAAAGTCTCCTCAGGTGCCCTCTTGGTAGGGCGAGGGA GGACAGGACTGGCTGGAGGCTCCAGGAAGGTGCCAGCTCCCCCCGCTGAGCCCCCTCATC CTTCTTCTGTGCTGAGCGGCCCCAGAGAACAGCAGAGGGGACAATCTTTGCCCCCAAATA TAATTCANGGAAACTGAGGTGATGATAAAGGGAGAATCCCCTCCCTGGCCCCTTCCCCTC CTGTAGAAGTGAANGCGACAAGGGAGAAGGAAGAGTAAGGGCCCTGGGGACCGTGGTGGC TCAGAGCTCGAGGTCGTTTGAAGATGCGGGTGACAAGGGTGCCGAAGGCCAGGGCGGTGC CCGCCACACCGCGGAAGAGAACTCCCCGCAAGCCTGGCCCGGGCAGCTTGGCAAACCTCC ACTCCAAATTGGGACAAGGGCTTGGGGCCCCGCCCGACCCCCGTGCAGGCAGGCCCAACA GAAACGGTTTGGGCTGGCGGCCACCGGCC |
| Restriction Sites | Please inquire |
| ACCN | NM_031417 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_031417.2, NP_113605.2 |
| RefSeq Size | 4917 bp |
| RefSeq ORF | 2067 bp |
| Locus ID | 57787 |
| UniProt ID | Q96L34 |
| Protein Families | Druggable Genome, Protein Kinase |
| Gene Summary | This gene encodes a member of the microtubule affinity-regulating kinase family. These protein kinases phosphorylate microtubule-associated proteins and regulate the transition between stable and dynamic microtubules. The encoded protein is associated with the centrosome throughout mitosis and may be involved in cell cycle control. Expression of this gene is a potential marker for cancer, and the encoded protein may also play a role in Alzheimer's disease. Pseudogenes of this gene are located on both the short and long arm of chromosome 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010] Transcript Variant: This variant (2) includes an alternate exon, which results in a frameshift, compared to variant 1. The resulting protein (isoform 2) is shorter and has a distinct C-terminus, compared to isoform 1. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Role of Partitioning-defective 1/Microtubule Affinity-regulating Kinases in the Morphogenetic Activity of Helicobacter pylori CagA
,Huaisheng Lu, Naoko Murata-Kamiya, Yasuhiro Saito, and Masanori Hatakeyama,
J. Biol. Chem., Aug 2009; 284: 23024 - 23036
[MARK4]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222580 | MARK4 (Myc-DDK-tagged)-Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2 |
CNY 5,040.00 |
|
| RC222580L1 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2, Myc-DDK-tagged |
CNY 7,440.00 |
|
| RC222580L2 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2, mGFP tagged |
CNY 9,120.00 |
|
| RC222580L3 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2, Myc-DDK-tagged |
CNY 9,120.00 |
|
| RC222580L4 | Lenti ORF clone of Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2, mGFP tagged |
CNY 9,120.00 |
|
| RG222580 | MARK4 (tGFP-tagged) - Human MAP/microtubule affinity-regulating kinase 4 (MARK4), transcript variant 2 |
CNY 6,640.00 |
