PDZD8 (NM_173791) Human Untagged Clone
CAT＃: SC107070
PDZD8 (untagged)-Human PDZ domain containing 8 (PDZD8)
CNY 10450.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | PDZK8 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_173791, the custom clone sequence may differ by one or more nucleotides
ATGGGGCTGCTGCTCATGATCCTGGCGTCGGCCGTGCTGGGTTCCTTCCTCACGCTCCTCGCCCAGTTCT TCCTGCTGTACCGCAGACAGCCCGAGCCGCCGGCGGACGAGGCCGCCCGCGCGGGCGAGGGCTTCCGCTA CATCAAGCCAGTGCCGGGCCTGCTCCTAAGGGAGTACCTTTATGGCGGCGGCCGGGATGAGGAGCCCTCC GGAGCGGCCCCTGAGGGCGGCGCGACCCCCACCGCGGCCCCCGAGACCCCCGCCCCGCCGACGCGGGAGA CTTGCTACTTCCTCAACGCCACCATCCTATTCCTGTTCCGGGAGTTGCGGGACACCGCGCTGACCCGCCG CTGGGTCACCAAGAAGATCAAGGTGGAGTTCGAGGAGCTGCTGCAGACCAAGACGGCCGGGCGCCTGCTG GAGGGGCTGAGCCTGCGGGACGTGTTCCTGGGCGAGACGGTGCCCTTCATCAAGACCATCCGGCTCGTGC GGCCAGTCGTGCCCTCGGCCACCGGGGAGCCCGATGGCCCTGAAGGGGAGGCGCTGCCCGCCGCCTGCCC CGAGGAGCTGGCCTTCGAGGCGGAGGTGGAGTACAACGGGGGCTTCCACCTGGCCATCGACGTGGACCTG GTCTTCGGCAAGTCCGCCTACTTGTTTGTCAAGCTGTCCCGCGTGGTGGGAAGGCTGCGCTTGGTCTTTA CGCGCGTGCCCTTCACCCACTGGTTCTTCTCCTTCGTGGAAGACCCGCTGATCGACTTCGAGGTGCGCTC CCAGTTTGAAGGGCGGCCCATGCCCCAGCTCACCTCCATCATCGTCAACCAGCTCAAGAAGATCATCAAG CGCAAGCACACCCTACCGAATTACAAGATCAGGTTTAAGCCGTTTTTTCCATACCAGACCTTGCAAGGAT TTGAAGAAGATGAAGAGCATATCCATATACAACAATGGGCACTTACTGAAGGCCGTCTTAAAGTTACGTT GTTAGAATGTAGCAGGTTACTCATTTTTGGATCCTATGACAGAGAGGCAAATGTTCATTGTACACTTGAG TTAAGCAGTAGTGTTTGGGAAGAAAAACAGAGGAGTTCTATTAAGACGGTTGAATTAATAAAAGGAAATT TACAAAGTGTTGGACTTACACTTCGTCTTGTCCAGTCAACTGATGGGTATGCTGGGCACGTCATCATTGA AACTGTGGCTCCAAACTCGCCTGCTGCAATTGCAGATCTTCAGCGGGGAGATCGACTTATCGCCATTGGA GGTGTGAAAATCACATCAACACTGCAAGTGTTGAAGCTTATCAAGCAGGCTGGTGACCGAGTCCTGGTGT ACTATGAAAGGCCTGTTGGCCAGAGTAATCAAGGTGCAGTGCTGCAAGATAACTTTGGCCAGTTGGAAGA AAACTTTTTGTCAAGCTCATGCCAATCGGGTTATGAAGAGGAAGCTGCCGGGTTGACAGTAGATACTGAA AGTAGAGAGCTGGATTCTGAATTTGAAGACTTGGCAAGTGATGTCAGAGCACAAAATGAGTTCAAAGATG AGGCACAATCATTAAGTCATAGTCCCAAACGTGTTCCAACAACACTTTCTATTAAACCCCTTGGAGCTAT ATCACCAGTTTTAAACCGTAAATTAGCTGTAGGAAGTCACCCACTACCACCGAAAATTCAGTCCAAAGAT GGAAATAAACCTCCACCCCTAAAAACTTCTGAGATAACAGACCCAGCACAAGTGTCAAAACCAACCCAAG GATCTGCTTTCAAACCACCTGTGCCACCACGACCACAAGCGAAAGTTCCTTTGCCTTCCGCCGATGCTCC AAATCAGGCAGAACCAGATGTTCTCGTTGAAAAGCCAGAGAAGGTGGTGCCACCTCCTCTTGTAGATAAA TCTGCTGAAAAGCAAGCAAAAAATGTGGATGCCATAGACGATGCAGCTGCACCTAAGCAATTTTTAGCAA AGCAAGAAGTGGCCAAAGATGTCACTTCAGAAACTTCCTGCCCTACTAAGGACAGTTCGGACGACCGTCA AACATGGGAATCATCAGAAATTCTTTATCGTAATAAGCTAGGAAAATGGACAAGAACCAGAGCATCCTGT TTGTTTGACATAGAAGCCTGTCACAGGTACTTAAACATTGCATTGTGGTGCAGGGATCCTTTCAAGTTGG GAGGTCTCATCTGTTTGGGGCATGTTAGTTTAAAACTTGAAGATGTGGCTTTAGGATGCCTAGCTACATC AAACACGGAATACCTTTCCAAATTGAGACTGGAAGCCCCCTCACCTAAGGCTATAGTCACTAGAACCGCA CTACGCAATCTGAGTATGCAAAAGGGATTCAATGACAAATTTTGCTATGGTGACATTACTATTCACTTCA AATATTTGAAAGAAGGAGAATCAGACCACCATGTAGTTACTAACGTAGAAAAAGAAAAAGAACCCCATTT GGTTGAAGAAGTTTCTGTTCTCCCTAAAGAGGAGCAATTTGTTGGACAGATGGGTTTAACAGAAAACAAA CACAGTTTTCAGGATACTCAGTTCCAGAACCCAACATGGTGTGACTACTGTAAGAAAAAAGTTTGGACTA AAGCAGCTTCCCAGTGTATGTTTTGTGCTTATGTTTGCCATAAAAAATGTCAAGAAAAGTGTCTAGCTGA GACTTCTGTTTGTGGAGCAACTGATAGGCGAATAGACAGGACACTGAAAAACCTTAGGCTGGAAGGACAG GAAACCCTCTTAGGCCTGCCTCCTCGTGTTGATGCTGAAGCTAGCAAGTCAGTCAATAAAACAACAGGTT TGACAAGGCATATTATCAATACTAGTTCTCGTTTATTAAATTTGCGTCAAGTCTCTAAAACTCGCCTTTC TGAACCAGGAACCGATCTCGTAGAACCTTCACCAAAACACACACCCAACACGTCAGACAACGAAGGCAGT GACACGGAGGTCTGTGGTCCAAACAGTCCTTCTAAACGGGGAAACAGCACAGGAATAAAGTTAGTGAGAA AAGAGGGTGGTCTGGATGACAGTGTTTTCATTGCAGTTAAAGAAATTGGTCGTGATCTGTACAGGGGCTT GCCTACAGAGGAAAGGATCCAGAAACTAGAGTTCATGTTGGATAAGCTACAGAATGAAATTGATCAGGAG TTGGAACACAATAATTCCCTTGTTAGAGAAGAAAAAGAGACAACTGATACAAGGAAAAAATCACTTCTTT CTGCTGCCTTAGCTAAATCAGGTGAAAGGCTACAAGCTCTAACACTTCTTATGATTCACTACAGAGCAGG CATTGAAGATATAGAAACTTTAGAAAGTCTGTCTTTAGACCAGCACTCCAAAAAAATAAGCAAGTACACA GATGATACAGAAGAAGACCTTGATAATGAAATAAGCCAACTAATAGACTCTCAGCCATTCAGCAGCATAT CAGATGACTTATTTGGCCCATCCGAGTCTGTGTAG >OriGene 5' read for NM_173791 unedited
GGATTTTGTAATACGACCTCACTATAGGGCGGCCGCGAATTCGCACGAGGCGGAGGCGGT GGCGGGATGGGGCTGCTGCTCATGATCCTGGCGTCGGCCGTGCTGGGTTCCTTCCTCACG CTCCTCGCCCAGTTCTTCCTGCTGTACCGCAGACAGCCCGAGCCGCCGGCGGACGAGGCC GCCCGCGCGGGCGAGGGCTTCCGCTACATCAAGCCAGTGCCGGGCCTGCTCCTAAGGGAG TACCTTTATGGCGGCGGCCGGGATGAGGAGCCCTCCGGAGCGGCCCCTGAGGGCGGCGCG ACCCCCACCGCGGCCCCCGAGACCCCCGCCCCGCCGACGCGGGAGACTTGCTACTTCCTC AACGCCACCATCCTATTCCTGTTCCGGGAGTTGCGGGACACCGCGCTGACCCGGCGCTGG GTCACCAAGAAGATCAAGGGGGAGTTCGAGGAGCTGCTGCAACCAAGACCGGCCGGCGCC TGCTGGAGGGCTGAGCCTGCGGACGTGTTCCTGGGCGAGACGTGCCCTTCATCAAGACAT CCCGCTCGTGCGGNCAGTCGTGGCCTCCGGCACCGGGGAAGCCGATTGCCCTTGAAGGGA AGCGCCTGTCCGGCGNCTTGCCCCGAGGAGCTTGCCTCTTCAGCCGAAGGTGAGTACAAC GGGGCCTTNCACCTGCCATTGACGTTGACCTTGGTCTCCGGCAGTTCCGCTACTTGGTTG TTCAAGCTGTCCCGCTTGGTGGGGAAGCTGCGCTTGGTCTTTACGCGCGTGCCCTTCACC CACTGGTTCTTCTCCTTCGTGGAAGACCCGCTGATCGACTTCGAGTGCGCTCCAGTTTGA AGGGCGGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_173791 |
| Insert Size | 3300 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_173791.2, NP_776152.1 |
| RefSeq Size | 3853 bp |
| RefSeq ORF | 3465 bp |
| Locus ID | 118987 |
| UniProt ID | Q8NEN9 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | Molecular tethering protein that connects endoplasmic reticulum and mitochondria membranes (PubMed:29097544). PDZD8-dependent endoplasmic reticulum-mitochondria membrane tethering is essential for endoplasmic reticulum-mitochondria Ca(2+) transfer (PubMed:29097544). In neurons, involved in the regulation of dendritic Ca(2+) dynamics by regulating mitochondrial Ca(2+) uptake in neurons (PubMed:29097544). Plays an indirect role in the regulation of cell morphology and cytoskeletal organization (PubMed:21834987). May inhibit herpes simplex virus 1 infection at an early stage (PubMed:21549406).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC205601 | PDZD8 (Myc-DDK-tagged)-Human PDZ domain containing 8 (PDZD8) |
CNY 12048.00 |
|
| RC205601L3 | Lenti-ORF clone of PDZD8 (Myc-DDK-tagged)-Human PDZ domain containing 8 (PDZD8) |
CNY 11780.00 |
|
| RC205601L4 | Lenti-ORF clone of PDZD8 (mGFP-tagged)-Human PDZ domain containing 8 (PDZD8) |
CNY 11780.00 |
|
| RG205601 | PDZD8 (tGFP-tagged) - Human PDZ domain containing 8 (PDZD8) |
CNY 10830.00 |
