EVER2 (TMC8) (NM_152468) Human Untagged Clone
CAT＃: SC101329
TMC8 (untagged)-Human transmembrane channel-like 8 (TMC8)
CNY 15120.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | EV2; EVER2; EVIN2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_152468, the custom clone sequence may differ by one or more nucleotides
ATGCTGCTGCCGCGGTCGGTGTCATCGGAGCGGGCCCCTGGGGTGCCGGAGCCGGAGGAGCTGTGGGAGG CAGAGATGGAGCGGCTGCGCGGCTCTGGGACGCCCGTGCGCGGGCTGCCCTATGCCATGATGGACAAGCG CCTCATCTGGCAGCTGCGGGAGCCCGCGGGGGTGCAGACCTTGCGCTGGCAGCGGTGGCAGCGCCGGCGG CAGACGGTGGAAAGGCGCCTGCGGGAGGCAGCGCAGCGGCTGGCCCGGGGCCTTGGGCTCTGGGAGGGGG CGCTCTACGAGATCGGGGGCCTCTTCGGCACAGGAATTCGGTCCTACTTCACCTTCCTCCGCTTCCTGCT GCTACTCAACCTGCTGAGCCTGCTGCTCACCGCAAGCTTCGTGCTGCTGCCCCTGGTCTGGCTCCGCCCC CCTGACCCAGGCCCCACCCTGAACTTGACCCTCCAGTGCCCTGGTAGCCGCCAGTCCCCGCCTGGCGTTT TGAGGTTCCACAATCAACTTTGGCATGTTTTGACTGGCAGGGCCTTCACCAACACCTATCTCTTCTACGG TGCGTACCGAGTGGGGCCGGAGAGCAGCTCCGTGTACAGCATCCGCCTGGCCTACCTCCTCAGCCCGCTG GCCTGCCTGCTCCTCTGCTTCTGTGGGACTCTGCGGCGGATGGTGAAGGGGCTGCCGCAGAAGACTCTGC TGGGTCAGGGCTATCAGGCGCCTCTCAGCGCCAAGGTCTTCTCCTCATGGGACTTCTGCATCCGGGTGCA GGAAGCAGCCACCATCAAGAAGCATGAGATCAGCAACGAGTTCAAGGTGGAGCTGGAGGAGGGCCGTCGC TTCCAGCTGATGCAGCAGCAGACCCGGGCCCAGACGGCCTGCCGCCTGCTCTCCTACCTGCGGGTCAACG TACTCAACGGGCTCCTGGTGGTTGGGGCCATCAGCGCCATCTTCTGGGCTACCAAGTACTCACAGGACAA CAAGGAGGAGTCCCTGTTTCTGCTGCTCCAGTACCTGCCCCCTGGGGTCATCGCCCTGGTCAACTTCCTG GGTCCCCTGCTGTTCACATTTCTGGTCCAGCTGGAGAACTACCCTCCCAACACGGAGGTCAACCTCACTC TGATCTGGTGCGTGGTGCTGAAGCTGGCCAGCTTGGGGATGTTCTCCGTCTCCCTGGGTCAGACCATACT GTGCATTGGCAGAGACAAGAGCAGCTGTGAGTCCTACGGCTACAACGTTTGTGACTATCAGTGCTGGGAG AACTCCGTGGGGGAGGAGCTGTACAAGCTGAGTATCTTCAACTTCCTCCTCACCGTGGCCTTCGCCTTCC TGGTCACCCTGCCTCGGAGGCTGCTGGTGGACCGGTTCTCAGGCCGGTTCTGGGCCTGGCTGGAACGGGA GGAGTTCCTGGTCCCCAAGAATGTGCTGGACATCGTGGCGGGGCAGACGGTCACCTGGATGGGCCTCTTC TACTGCCCCCTGCTGCCCCTGCTGAATAGCGTCTTCCTCTTCCTCACCTTCTACATCAAGAAGTACACCC TCCTGAAGAACTCCAGGGCATCTTCGCGGCCCTTCCGTGCCTCCAGCTCCACCTTCTTCTTCCAGCTAGT GCTCCTCCTGGGCCTGCTTCTGGCTGCAGTGCCCCTGGGCTATGTGGTCAGCAGCATCCACTCCTCCTGG GACTGCGGCCTCTTCACCAACTACTCAGCACCCTGGCAAGTGGTCCCGGAGCTGGTGGCCCTTGGGCTCC CGCCCATTGGCCAGCGTGCCCTCCACTACCTGGGCTCCCACGCCTTCAGCTTCCCCCTCCTCATCATGCT CAGCCTTGTCCTGACGGTGTGCGTCTCCCAGACCCAGGCCAATGCCAGGGCCATCCACAGGCTCCGGAAG CAGCTGGTGTGGCAGGTTCAGGAGAAGTGGCACCTGGTGGAGGACCTGTCGCGACTGCTGCCGGAGCCAG GCCCGAGCGACTCTCCGGGCCCCAAGTACCCTGCCTCCCAAGCTTCGCGCCCGCAGTCCTTCTGCCCCGG ATGCCCATGCCCTGGCTCCCCGGGCCACCAGGCCCCGCGGCCGGGCCCCTCCGTCGTGGATGCCGCGGGA CTGCGTTCCCCTTGCCCTGGACAGCACGGTGCCCCGGCCTCCGCCCGCAGATTCCGCTTCCCCAGCGGCG CGGAGCTGTAA >OriGene 5' read for NM_152468 unedited
AGTATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACCAGCCAGGNACTT GGTCCCTAGGTCCCCAGATGGGGAGACTGAGGCCGTGGCTGTGTGTCCCTCTGAGAGTTG GAGCGGGGCTGGGCCCGAATTCGACCCCAGCAGGATTCTCTCTCATTTCTGAGCCCCGGA GGTGGCAGAGCGGCAGACCCGGGCAAGTGAACCCTAGGGCTGCAGGAGCCCAGGCCCCGA CGCCGGCGCAGAGGGGACGGAAGGGCCCGCCCCCAGCCCAGCGTGCACAGAGGCCATAGC CAAGGCCTTAAGGCTCATCCAACCGGGGACTCATATCCCCCCCACCGGCAGCCCGGCGCC CCAGCCTCTACCCGTGCCCGCCGAGATGCTGCTGCCGCGGTCGGTGTCATCGGAGCGGGC CCCTGGGGTGCCGGAGCCGGAGGAGCTGTGGGAGGCAGAGATGGAGCGGCTGCGCGGCTC TGGGACGCCCGTGCGCGGGCTGCCCTATGCCATGATGGACAAGCGCCTCATCTGGCCTCT TCGGCACAGGAATTCGGTCCTACTTCACCTTCCTCCGCTTTCTGCTGCTACTCAACCTGC TGAGCCTGCTGCTCACCGCAAGCTTCGTGCTGCTGCCCCTGGGCTGGCTCCGGCCCCCTG ACCCAGCCCCACCCTGAACTTGACCCTTCAGTGCCCTGGTAGCCGNCACGTCCCGCCTGG CGTTTTGAAGTTCCACACTCAACTCTGGCATGTTTTGACTGTCAGGGCCTTTACCACCAC TAACTCTTCTACCGTGCGTACCGAGTGGGCCCGGAAAGCANTTCGTGTACAGCATTCGGC TGGGCTACTCCCTAGACCGCTGGCTGCCTGCTCTTTGTTTTGTGGACTCTCCGCCGAGGT GAAGGGCTGCCCCAAAAACTTGTTTTTCAGGGTTTAAGCGCCTTATGCCCAGTGTTCCTC ATGGACTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_152468 |
| Insert Size | 2500 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_152468.3, NP_689681.2 |
| RefSeq Size | 4419 bp |
| RefSeq ORF | 4419 bp |
| Locus ID | 147138 |
| UniProt ID | Q8IU68 |
| Protein Families | Transmembrane |
| Gene Summary | Epidermodysplasia verruciformis (EV) is an autosomal recessive dermatosis characterized by abnormal susceptibility to human papillomaviruses (HPVs) and a high rate of progression to squamous cell carcinoma on sun-exposed skin. EV is caused by mutations in either of two adjacent genes located on chromosome 17q25.3. Both of these genes encode integral membrane proteins that localize to the endoplasmic reticulum and are predicted to form transmembrane channels. This gene encodes a transmembrane channel-like protein with 8 predicted transmembrane domains and 3 leucine zipper motifs. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210309 | TMC8 (Myc-DDK-tagged)-Human transmembrane channel-like 8 (TMC8) |
CNY 7976.00 |
|
| RC210309L1 | Lenti-ORF clone of TMC8 (Myc-DDK-tagged)-Human transmembrane channel-like 8 (TMC8) |
CNY 10376.00 |
|
| RC210309L2 | Lenti-ORF clone of TMC8 (mGFP-tagged)-Human transmembrane channel-like 8 (TMC8) |
CNY 5890.00 |
|
| RC210309L3 | Lenti-ORF clone of TMC8 (Myc-DDK-tagged)-Human transmembrane channel-like 8 (TMC8) |
CNY 5890.00 |
|
| RC210309L4 | Lenti-ORF clone of TMC8 (mGFP-tagged)-Human transmembrane channel-like 8 (TMC8) |
CNY 5890.00 |
|
| RG210309 | TMC8 (tGFP-tagged) - Human transmembrane channel-like 8 (TMC8) |
CNY 4370.00 |
