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Slc8b1 (NM_001017488) Rat Tagged Lenti ORF Clone
CAT＃: RR205249L3
- LentiORF®
Lenti ORF clone of Slc24a6 (Myc-DDK-tagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug)
"NM_001017488" in other vectors (3)
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CNY 9,410.00
Product images
CNY 600.00
Specifications
| Product Data | |
| Type | Rat Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | Slc24a6 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | Puromycin |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR205249).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_001017488 |
| ORF Size | 1755 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_001017488.1, NP_001017488.1 |
| RefSeq Size | 2693 bp |
| RefSeq ORF | 1758 bp |
| Locus ID | 498185 |
| UniProt ID | Q6AXS0 |
| Gene Summary | Mitochondrial sodium/calcium antiporter that mediates sodium-dependent calcium efflux from mitochondrion, by mediating the exchange of 3 sodium ions per 1 calcium ion. Plays a central role in mitochondrial calcium homeostasis by mediating mitochondrial calcium extrusion: calcium efflux is essential for mitochondrial function and cell survival, notably in cardiomyocytes (By similarity). Regulates rates of glucose-dependent insulin secretion in pancreatic beta-cells during the first phase of insulin secretion: acts by mediating efflux of calcium from mitochondrion, thereby affecting cytoplasmic calcium responses. Required for store-operated Ca(2+) entry (SOCE) and Ca(2+) release-activated Ca(2+) (CRAC) channel regulation: sodium transport by SLC8B1 leads to promote calcium-shuttling that modulates mitochondrial redox status, thereby regulating SOCE activity (By similarity). Involved in B-lymphocyte chemotaxis (By similarity). Able to transport Ca(2+) in exchange of either Li(+) or Na(+), explaining how Li(+) catalyzes Ca(2+) exchange. In contrast to other members of the family its function is independent of K(+) (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RN205249 | Slc24a6 (untagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug) |
CNY 7,410.00 |
|
| RR205249 | Slc24a6 (Myc-DDK-tagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug) |
CNY 7,410.00 |
|
| RR205249L4 | Lenti ORF clone of Slc24a6 (mGFP-tagged ORF) - Rat solute carrier family 24 (sodium/potassium/calcium exchanger), member 6 (Slc24a6), (10 ug) |
CNY 10,260.00 |
