Rtel1 (NM_001191857) Rat Untagged Clone

Specifications

Product Data
Type	Rat Untagged Clone
Tag	Tag Free
Synonyms	RGD1306721
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	Fully Sequenced ORF (showhide) >RN217571 representing NM_001191857 Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCCAGGGTAGTCCTGAATGGTGTGACAGTGGATTTCCCTTTCCAGCCCTACCCATGCCAGCAGGAAT ATATGACCAAGGTGCTAGAATGTCTCCAGAAGAAAGTGAATGGCATCCTCGAGAGCCCCACTGGCACTGG GAAGACGCTATGCCTCCTCTGCACTACATTGGCCTGGCGGGAACATCTCCGAGATGCCGTTTCTTCCCTA AAGATTGCTGAGAGAGTTCAAGGGGAACTCTTTGCCAGTCGGACCTTGTCATCCTGGAGGAGTGCTGCTG ATGCCAATGGAGACTCAATAGATTGCTACACAGATATCCCAAAGATCATCTATGCTTCTAGAACTCACTC ACAGCTAACTCAGGTCATCGGTGAGCTTCGGAATACTTCCTACCGGCCCAAGGTGTGTGTGCTGGGCTCC CGGGAGCAGCTGTGTATTCATCCCGAAGTGAAGAAGCAAGAGAGTAACCACATGCAGATCAGTTTGTGCC GTAAGAAGGTGGCAAGTCGCTCCTGTCATTTCTACAACAATGTGGAAGAGAAAAGCCTGGAGCAAGAGCT GGCTACCCCCATCTTGGATATTGAGGACCTTGTGAAGAACGGAAGCAAACACAAAGTGTGCCCATACTAC CTCTCTCGAAACCTGAAGCAGCAAGCTGATATCATCTTTATGCCATACAATTACTTGTTGGATGCTAAGA GTCGTAAGGCACACAACATTGACCTGAAGGGAACGGTTGTAATCTTTGATGAAGCTCACAATGTGGAAAA GATATGTGAGGAGTCAGCCTCCTTTGACTTGACTCCCCGAGATGTGGCTTCAGGACTGGAGGTTATCAAC CAGGTTTTGGAGGAGCAAGCCCGGGTGGCTCAGCATGGTGAACTCCAACAGGAGTTCATTATAGACACGT CCAGCTCAGGTCTCAACATGGAGCTGGAAGACATCGCAAAGTTGAAGATGATCCTGCTGCACCTGGAGGA GGCTATTGATGCTGTTCAGCTGCCTGGGGATGACAGAGGAGTCACCAAACCTGGAAGCTACATCTTCGAG CTGTTTGCTGAAGCACAAATAACATTTCAAACCAAAGGCTGCATTTTGGAGTCGCTGGACCAGATAATCC AGCACCTGACAGGACGCACTGGTGTGTTCACCAACACGGCTGGGTTGCAGAAGCTCATGGACATTATCCA GATTGTGTTCAGCGTGGACCCTCTGGAAGGCAGCCCTGGTTCTCAGGTGGGGCTGGGTAGCTCACATTTC TATAAGGTACACATACACCCTGAAACCAGCCACCGGAGAGCAGCTCAGCGGTCAGATGCCTGGAGTACCA CTGCATCCAGGAAACAAGGGAAGGTGCTGAGCTATTGGTGCTTCAGTCCCAGCCACAGCATGCGTGAACT GGTCCAGCAAGGAGTCCGTACCCTTATCCTCACCAGTGGTACACTGGCTCCGCTGTCTTCCTTTGCTCTG GAGATGCAAATTCCATTCCCAGTCTGTCTGGAGAATCCACACATCATTGACAAGAACCAGCTCTGGGTAG GGGTTATCCCCAGAGGACCTGATGGTGTTCAGCTAAGCTCTGCCTATGACAAAAGGTTTTCTGAAGAGTG CTTATCTTCCCTGGGGAAGGCTCTGGGCAACATTGCTCGTGTGGTGCCCCATGGGCTTCTGGTCTTCTTC CCTTCCTACCCTGTCATGGAGAAAAGCCTGGAGTTCTGGCAGGCGCAAGGCATGTCCAAAAAGGTAGAGG CACTGAAGCCTCTATTCGTGGAACCCAGGAACAAAGGCAGCTTCTCAGAGGTCATTGATGCCTACTACCA GCAAGTTGCCTCCCCTGGGTCTAATGGGGCCACCTTCTTAGCAGTGTGTCGAGGAAAGGCCAGTGAAGGG CTGGACTTCTCAGACATGAATGGTCGTGGTGTGATTGTCACGGGCCTCCCATATCCCCCACGCATGGATC CCCGTGTTATCCTCAAGATGCAGTTCTTGGATGAGATGAAAGGCCGGAGTAGGGTTGGAGGCCAGTGCCT CTCTGGACAGGAATGGTACCAGCAACAAGCATCCAGGGCTGTGAACCAGGCTATTGGGAGGGTTATCCGA CACCGCCATGACTATGGGGCCATCTTCTTATGTGACCACAGGTTTGCCTATGCTGATGCCAGGGCCCATC TGCCCTCCTGGGTGCGCCCCTACCTCAAGGTGTATGACAACTTTGGCCGTGTCATCCGAGATGTGGCCCA GTTCTTCCGTGTTGCTCAGAAAGCTATGCCTTTGCCAGTTCCTCAGGCTGTGACCTCAAGTGTGAGTGAG GGAGAAGCTGCTGTCAAGGAGGCCACATTGTCCAGCCACTCCCTCTCCACCAGGAAAGCCATGAGCTTGG ATGTGCATGTGCCCAGCCTGAGGCGGAGGCCCGTAGGATTACCGACTGCTGGAGACTCCGAGAGCAGCGT ATGTGTGGAGTATGAGCAGCAGACATTTTCTGCCCAGAAGAGACCCATGGGGCTGCTAGCTGCCTTAGAG TACAACGAGCAGAAGGCTGGGGCATCTGAGGAGCAGGCACTCAGCTCCTCCACCCCATCTCTCCGGTGTG AAAAGAGGCTGTCCGTTGAGCAAAGAGGAGGAAAGAAGAAAGTCAGGCTGGTCAACCATCCGGAGGAACC AGTGGCTGGCACACAGGCAGGCAGAGCCAAGATGTTCATGGTGGCCGTGAAGCAAGCACTGAGCCAAGCT AACTTTGACACCTTTACCCAGGCCCTGCAGCACTATAAGAGTTCTGATGACTTTGAAGCCCTAGTGGCCT CTCTCACCTGCCTCTTTGCTGAAGACCCCAAGAAACACACCCTACTTAAAGGTTTCTACCAGTTTGTACG ACCCCACCACAAGCAGCAGTTTGAGGACATCTGCTTCCAGCTAACAGGCCAACGATGTAGCTACCAGCCA GGAAACAGCCTTCCCTTTGGAGAGCAAGCACAGTCAACTGCCAGTAAGCAAGGAAGGAGAGAGCTGGAAT CTAAACTGACCTTGTCTGAAGGTGCAGATAGGCAGCTGGATCCTGGAGAGCACCTGAATCAGGGGTGGCC TCACCTGTCTACCCATCTAACCTCCAAAGGAGACACCAGCAATTGTCCAAAAGTGGGATGTGTGGGAGAA AAACCTGGCCAGCCTGCTGTGAATGACTACCTATCTGACGTCCACAAAGCTCTGGGATCTGCAAGCTGCA ACCAGCTTACGGCAGCTCTGAGGGCATACAAACAGGATGATGACCTGGACAAAGTGCTGGCTGTGGTGGC AGCATTGACCACTGCAAAACCTGAACACTTATCTTTGCTACAGAGATTTGGCATGTTTATACGTCGGCAT CATAAGCCTCGGTTTGTACAGACCTGTGCAGACCTAATGGGCCTACCTACCATAGGCAAGGGCTTGGAGC TCCCATGTCCCAGGGATGAGAGTACAACTGTGCCTTCTGAGCTTACTCATGAGGACATGAAACCAGGGCC CTCGACGTCCAAGAAACCTGAGAAGACCCAGAGTAAGATCTCATCCTTCCTTAGACAGAGGCCAGACCAG AGTGCGAGGTCTGATGATACCATAATGCAGCTTCCTCCCAGACTACCCCCTGAACACACGACGTCTCAGT GGAATTTTGTATGCCCAGCCTGTGCAACTGAGGATACAGTGCTTTTCCAGTGCCCTTCCTGTGACTTCTG CCGCTGCCGGGCCTGCTGGCAACGTCAACTCCAGGCCTCTAGACTGTGTCCAGCTTGTGGTGCTGTTAAC AGGAAGCAGAGCATTGCACAGGTCATCTGGCCGAAGCCCCAGTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA
Restriction Sites	SgfI-MluI
ACCN	NM_001191857
Insert Size	3825 bp
OTI Disclaimer	Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
OTI Annotation	Clone contains native stop codon, and expresses the complete ORF without any c-terminal tag.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq	NM_001191857.1, NP_001178786.1
RefSeq Size	4237 bp
RefSeq ORF	3825 bp
Locus ID	362288
UniProt ID	Q5RJZ1
Gene Summary	ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by counteracting telomeric G4-DNA structures, which together ensure the dynamics and stability of the telomere.[UniProtKB/Swiss-Prot Function]

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.