Pak7 (NM_001107781) Rat Untagged Clone
CAT＃: RN203432
Pak7 (untagged ORF) - Rat p21 (CDKN1A)-activated kinase 7 (Pak7), (10 ug)
CNY 9220.00
Product images
Specifications
| Product Data | |
| Type | Rat Untagged Clone |
| Tag | Tag Free |
| Synonyms | PAK-5; PAK-7; Pak5 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RN203432 representing NM_001107781
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTTTGGGAAGAAAAAGAAAAAGATCGAAATATCCGGCCCATCTAACTTTGAACACAGGGTTCATACTG GGTTTGATCCACAAGAGCAGAAGTTTACTGGCCTTCCCCAGCAGTGGCACAGCCTGTTAGCAGACACAGC CAACAGGCCCAAGCCTATGGTGGATCCATCATGCATCACACCCATACAACTGGCTCCCATGAAGACAATC GTCAGAGGAAATAAATCCTGCAAGGAAAGCTCTATCAACGGTCTGCTAGAGGATTTCGACAACATCTCCG TGACTCGCTCCAACTCCCTAAGGAAAGAAAGCCCACCCACCCCAGATCAGGGAGCAGCTAGCCGCATTCA AGGCCACTCCGAAGAAAACGGCTTCATTACTTTCTCACAATATTCTAGTGAATCTGATACTACTACGGAC TACACAACTGAAAAGTATAGAGACAGGAGTCTCTATGGAGACGACCTGGATCTGTACTATAGAGGCAGCC ATGCAGCCAAGCAAAACGGGCATGCTATGAAGATGAAACATGGAGATGCCTACTATCCTGAGATGAAGCC TTTGAAATCCGACCTGGCCAGATTCCCTGTCGACTATCACACACACTTGGACTCGCTGAGCAAAGCAAGT GAGTACGGTGACCTCAAGTGGGATTATCAGCGAGCCTCCAGTAGCTCCCCTCTGGACTACTCATTCCAGC TCACGCCTTCCAGAACTGCAGGGACCAGCAGGTGCTCCAAGGAGAGTCTGGCATACAGTGAAAGTGATTG GGGACCCAGCTTTGATGACTATGATAGGAGGCCAAAATCATCCTACCTGCATCAGACAAGCCCTCAGCCA GCCATGCGCCAGAGATCCAAGTCAGGCTCAGGGCTTCAGGAACCCATGATGCCATTTGGAGCAAGTGCAT TTAAAACTCATCCTCAAGGACACTCGTACAACTCCTACACCTACCCTCGATTGTCTGAGCCCACAATGTG CATTCCAAAGGTGGATTATGATCGAGCACAGATGGTCTTCAGTCCTCCACTGTCAGGGTCCGACACCTAT CCCAGAGGCCCCACCAAACTACCTCAAAGTCAAAGCAAAGTGGGCTACTCTTCAAGTAGCCACCAGTATC CTGGGTACCACAAAGCATCCCTATACCATCATCCGTCCCTGCAAACCAGTTCTCAGTACATCTCCACCGC TTCTTACTTGAGCTCTCTCAGTATCTCCTCGAGCACCTACCCTCCACCCAGCTGGGGCTCCTCTTCAGAC CAGCAGCCCTCTAGGGTATCCCATGAACAGTTTCGAGCTGCCCTGCAACTGGTGGTCAGCCCAGGAGACC CCAGGGAATATTTGGATAACTTTATTAAAATCGGAGAAGGGTCGACAGGCATCGTGTGCATTGCAACAGA GAAGCACACAGGCAAGCAAGTGGCGGTGAAGAAAATGGACCTCCGAAAGCAACAGAGACGGGAACTCCTT TTTAATGAGGTCGTGATAATGCGTGATTACCACCATGACAATGTAGTTGACATGTATAACAGCTACCTTG TTGGAGATGAGCTCTGGGTGGTCATGGAGTTTCTAGAAGGTGGTGCCTTGACAGACATCGTCACTCATAC CAGAATGAATGAAGAACAGATAGCTACTGTCTGCCTGTCAGTTCTGAAAGCGCTGTCCTACCTTCATAAC CAAGGAGTGATTCACAGGGACATAAAGAGTGACTCCATTCTTCTGACAAGCGATGGCCGGATAAAGTTAT CTGACTTTGGCTTCTGTGCTCAAGTTTCCAAAGAGGTGCCAAAGAGGAAGTCACTGGTGGGTACCCCATA CTGGATGGCTCCTGAGGTGATTTCCAGGCTACCTTATGGGACAGAGGTGGACATCTGGTCCCTCGGGATA ATGGTGATAGAGATGATTGATGGTGAGCCTCCCTATTTCAATGAGCCTCCTCTGCAGGCCATGAGGAGGA TCCGGGACAGTTTACCTCCAAGAGTGAAGGACCTGCACAAGGTTTCTTCCATGCTCCGAGGATTCCTAGA TCTTATGTTGGTGAGGGAGCCCTCTCAAAGAGCCACAGCTCAAGAACTTCTTGGACATCCATTCTTAAAA TTGGCAGGCCCGCCATCTTGCATCGTTCCCCTCATGAGACAATATAGGCATCACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001107781 |
| Insert Size | 2157 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001107781.1, NP_001101251.1 |
| RefSeq Size | 4040 bp |
| RefSeq ORF | 2157 bp |
| Locus ID | 311450 |
| UniProt ID | D4A280 |
| Gene Summary | Serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RR203432 | Pak7 (Myc-DDK-tagged ORF) - Rat p21 (CDKN1A)-activated kinase 7 (Pak7), (10 ug) |
CNY 9220.00 |
|
| RR203432L3 | Lenti ORF clone of Pak7 (Myc-DDK-tagged ORF) - Rat p21 (CDKN1A)-activated kinase 7 (Pak7), (10 ug) |
CNY 11020.00 |
|
| RR203432L4 | Lenti ORF clone of Pak7 (mGFP-tagged ORF) - Rat p21 (CDKN1A)-activated kinase 7 (Pak7), (10 ug) |
CNY 12160.00 |
