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IRS4 (NM_003604) Human Tagged ORF Clone
CAT＃: RG218385
- TrueORF®
IRS4 (tGFP-tagged) - Human insulin receptor substrate 4 (IRS4)
ORF Plasmid: DDK
"NM_003604" in other vectors (6)
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CNY 10,352.00
Product images
CNY 1,000.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | CHNG9; IRS-4; PY160 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG218385 representing NM_003604
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGAGTTGCTCCTTCACTCGCGACCAAGCGACAAGAAGACTAAGAGGTGCAGCAGCGGCGGCAGCGG CAGCTCTAGCAGCAGTGGTGACCACCCCGCTTCTTTCCTCGGGAACCCCGACCGCACTCATTGGGACCGG GTCGTCTTGTCCGGGAGCCATGTGGCTCTCCACGGCCACTGGCTCCCGGTCAGACTCCGAGTCCGAAGAG GAGGACCTGCCCGTCGGGGAGGAAGTCTGCAAACGCGGCTACCTGCGGAAACAGAAGCATGGGCACAGGC GCTACTTCGTGCTCAAACTCGAGACTGCTGACGCCCCAGCTCGGCTGGAATACTACGAAAATGCCAGGAA GTTCCGGCACAGTGTCCGCGCCGCGGCGGCTGCAGCAGCGGCGGCCGCCTCTGGCGCCGCGATCCCCCCG CTCATTCCACCGCGGCGCGTGATCACCCTATACCAGTGCTTTTCCGTGAGCCAGCGAGCAGATGCAAGGT ACCGACACCTCATTGCTCTTTTCACCCAAGACGAATACTTCGCGATGGTGGCCGAGAACGAGTCGGAGCA GGAAAGCTGGTACTTGCTGCTCAGCCGCCTCATCCTCGAGAGCAAGCGCCGCCGCTGCGGCACGCTCGGC GCGCAGCCGGACGGAGAGCCGGCCGCGCTGGCGGCGGCAGCGGCGGCGGAGCCACCCTTCTATAAAGATG TGTGGCAGGTAATAGTCAAACCCAGGGGGCTGGGGCACAGAAAAGAGCTGAGCGGCGTGTTCCGGCTGTG TCTAACCGACGAGGAGGTCGTGTTTGTGAGGCTGAACACCGAAGTGGCCAGCGTGGTCGTCCAGCTCCTG AGCATCCGTCGCTGTGGACACTCGGAGCAGTATTTCTTCTTGGAAGTAGGCAGGTCCACTGTCATCGGTC CGGGAGAGCTCTGGATGCAGGTCGATGACTGTGTGGTTGCCCAAAACATGCATGAGCTGTTTTTGGAGAA GATGAGAGCCTTGTGTGCAGACGAATACAGAGCCCGCTGCCGCAGCTACAGCATCAGCATCGGCGCCCAC CTGTTAACCCTGCTGTCCGCTAGGAGGCACCTGGGCTTGGTGCCGCTCGAGCCGGGAGGCTGGCTCAGAA GGTCCCGCTTTGAGCAGTTTTGCCACCTCAGGGCCATCGGCGACGGGGAAGACGAGATGCTTTTCACCAG GCGCTTCGTAACACCCAGCGAGCCTGTGGCCCACTCCAGGCGAGGAAGACTGCACCTGCCCAGAGGGCGC AGGTCAAGGAGAGCGGTTTCAGTGCCGGCCAGCTTTTTTCGCCGCTTAGCACCCAGCCCAGCACGTCCCC GGCACCCTGCAGAAGCCCCGAACAATGGAGCTCGCCTGTCTTCTGAAGTGTCTGGTTCTGGCTCTGGCAA CTTTGGGGAGGAAGGCAATCCCCAGGGCAAAGAAGATCAGGAAGGAAGCGGAGGTGACTACATGCCTATG AACAATTGGGGCTCAGGAAATGGCCGGGGCTCAGGAGGTGGCCAGGGCTCAAATGGCCAAGGCTCCAGTA GCCATAGCTCGGGAGGAAACCAGTGTTCAGGCGAGGGACAGGGATCCCGAGGTGGTCAGGGCTCAAATGG CCAGGGCTCAGGAGGAAACCAGTGCTCTAGAGATGGCCAGGGCACCGCAGGTGGGCACGGTTCAGGTGGT GGCCAGAGACCTGGAGGTGGGCATGGCTCAGGTGGTGGCCAGGGACCTGGAGATGGCCATGGCTCAGGTG GTGGCAAGAACTCTGGGGGGGGCAAAGGCTCAGGAAGTGGGAAAGGATCCGATGGTGATGGTGAACGTGG AAAATCTCTGAAGAAAAGATCCTATTTTGGCAAATTAACTCAAAGCAAGCAACAGCAAATGCCACCACCT CCACCACCTCCTCCTCCACCCCCACCAGCTGGAGGAACTGGTGGAAAAGGGAAGTCTGGGGGAAGATTCA GACTTTATTTTTGTGTTGACAGAGGAGCCACGAAAGAATGCAAAGAAGCCAAAGAAGTGAAAGATGCAGA GATCCCAGAAGGTGCAGCTCGAGGTCCCCACAGAGCCAGAGCTTTTGATGAAGATGAGGATGACCCATAC GTGCCAATGAGGCCAGGGGTGGCCACCCCTCTTGTAAGCTCCAGTGATTATATGCCAATGGCTCCTCAAA ATGTCTCTGCTTCAAAAAAGCGCCACTCTCGATCCCCTTTTGAAGATTCAAGAGGGTACATGATGATGTT TCCCAGAGTGAGCCCACCACCTGCTCCGAGTCCTCCAAAAGCACCTGATACTAATAAAGAGGATGACTCA AAGGACAATGACAGTGAGAGTGACTACATGTTTATGGCTCCTGGAGCCGGTGCAATTCCAAAAAACCCCA GAAATCCTCAGGGTGGCTCTTCCTCCAAAAGTTGGAGCTCCTACTTCTCTCTACCAAACCCTTTTCGGAG CTCACCTTTGGGACAGAATGACAACAGTGAGTATGTGCCAATGTTACCTGGAAAGTTCCTGGGGAGGGGC CTAGACAAAGAAGTCTCCTATAACTGGGACCCCAAAGATGCAGCTTCAAAGCCTTCAGGTGAGGGATCAT TCTCAAAGCCTGGAGATGGGGGATCACCTTCAAAGCCTTCAGATCATGAGCCCCCAAAGAATAAAGCTAA GAGACCTAACCGACTTTCTTTTATTACAAAAGGATATAAAATCAAGCCAAAACCACAAAAGCCCACACAT GAGCAGAGAGAAGCTGACAGCTCTAGTGACTACGTCAACATGGACTTCACTAAAAGAGAGAGCAATACAC CAGCTCCCTCTACTCAAGGACTACCAGATTCGTGGGGCATAATTGCTGAACCCAGACAGTCAGCCTTTTC TAATTATGTGAATGTTGAGTTTGGAGTGCCATTTCCAAATCCAGCAAACGACCTCTCAGATCTTTTAAGA GCTATACCACGTGCCAACCCCTTATCTCTGGACAGTGCTAGGTGGCCACTTCCTCCCCTTCCCCTCAGTG CTACAGGTAGCAATGCTATTGAGGAAGAGGGTGACTACATTGAAGTAATTTTCAACTCAGCAATGACACC AGCCATGGCTCTTGCTGACAGTGCCATTCGCTATGATGCTGAAACAGGTCGAATCTATGTGGTCGACCCA TTTTCTGAGTGCTGTATGGATATTTCTCTCTCCCCCAGCCGATGTTCTGAACCACCACCTGTAGCTAGGC TGCTGCAGGAAGAAGAGCAGGAGAGAAGACGCCCACAAAGCCGTTCTCAAAGTTTCTTTGCAGCAGCCAG AGCCGCTGTCTCTGCTTTTCCAACAGACAGCCTCGAGAGAGACCTTTCCCCATCCTCAGCCCCGGCTGTC GCTTCGGCTGCAGAGCCGACTTTAGCCCTCAGCCAAGTTGTAGCTGCGGCCTCCGCGCTCGCCGCAGCCC CGGGCATCGGCGCAGCAGCCGCAGCTGCTGGATTTGACTCCGCCTCTGCCCGCTGGTTTCAACCTGTTGC TAATGCTGCTGATGCCGAAGCAGTAAGGGGAGCCCAAGACGTTGCCGGTGGCTCGAACCCTGGAGCCCAC AACCCATCTGCAAACCTTGCCAGAGGTGATAACCAGGCTGGCGGGGCTGCCGCTGCAGCTGCCGCTCCGG AACCACCACCTCGCAGTCGCCGGGTGCCAAGACCCCCGGAGAGAGAAGATTCTGACAACGACGACGACAC TCACGTGAGAATGGATTTTGCCAGACGTGATAATCAGTTCGACTCTCCCAAAAGAGGTCGG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG218385 representing NM_003604
Red=Cloning site Green=Tags(s) MASCSFTRDQATRRLRGAAAAAAAALAAVVTTPLLSSGTPTALIGTGSSCPGAMWLSTATGSRSDSESEE EDLPVGEEVCKRGYLRKQKHGHRRYFVLKLETADAPARLEYYENARKFRHSVRAAAAAAAAAASGAAIPP LIPPRRVITLYQCFSVSQRADARYRHLIALFTQDEYFAMVAENESEQESWYLLLSRLILESKRRRCGTLG AQPDGEPAALAAAAAAEPPFYKDVWQVIVKPRGLGHRKELSGVFRLCLTDEEVVFVRLNTEVASVVVQLL SIRRCGHSEQYFFLEVGRSTVIGPGELWMQVDDCVVAQNMHELFLEKMRALCADEYRARCRSYSISIGAH LLTLLSARRHLGLVPLEPGGWLRRSRFEQFCHLRAIGDGEDEMLFTRRFVTPSEPVAHSRRGRLHLPRGR RSRRAVSVPASFFRRLAPSPARPRHPAEAPNNGARLSSEVSGSGSGNFGEEGNPQGKEDQEGSGGDYMPM NNWGSGNGRGSGGGQGSNGQGSSSHSSGGNQCSGEGQGSRGGQGSNGQGSGGNQCSRDGQGTAGGHGSGG GQRPGGGHGSGGGQGPGDGHGSGGGKNSGGGKGSGSGKGSDGDGERGKSLKKRSYFGKLTQSKQQQMPPP PPPPPPPPPAGGTGGKGKSGGRFRLYFCVDRGATKECKEAKEVKDAEIPEGAARGPHRARAFDEDEDDPY VPMRPGVATPLVSSSDYMPMAPQNVSASKKRHSRSPFEDSRGYMMMFPRVSPPPAPSPPKAPDTNKEDDS KDNDSESDYMFMAPGAGAIPKNPRNPQGGSSSKSWSSYFSLPNPFRSSPLGQNDNSEYVPMLPGKFLGRG LDKEVSYNWDPKDAASKPSGEGSFSKPGDGGSPSKPSDHEPPKNKAKRPNRLSFITKGYKIKPKPQKPTH EQREADSSSDYVNMDFTKRESNTPAPSTQGLPDSWGIIAEPRQSAFSNYVNVEFGVPFPNPANDLSDLLR AIPRANPLSLDSARWPLPPLPLSATGSNAIEEEGDYIEVIFNSAMTPAMALADSAIRYDAETGRIYVVDP FSECCMDISLSPSRCSEPPPVARLLQEEEQERRRPQSRSQSFFAAARAAVSAFPTDSLERDLSPSSAPAV ASAAEPTLALSQVVAAASALAAAPGIGAAAAAAGFDSASARWFQPVANAADAEAVRGAQDVAGGSNPGAH NPSANLARGDNQAGGAAAAAAAPEPPPRSRRVPRPPEREDSDNDDDTHVRMDFARRDNQFDSPKRGR TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_003604 |
| ORF Size | 3771 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003604.2 |
| RefSeq Size | 3939 bp |
| RefSeq ORF | 3774 bp |
| Locus ID | 8471 |
| UniProt ID | O14654 |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus |
| Gene Summary | IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218385 | IRS4 (Myc-DDK-tagged)-Human insulin receptor substrate 4 (IRS4) |
CNY 8,752.00 |
|
| RC218385L1 | Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), Myc-DDK-tagged |
CNY 11,152.00 |
|
| RC218385L2 | Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), mGFP tagged |
CNY 14,440.00 |
|
| RC218385L3 | Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), Myc-DDK-tagged |
CNY 14,440.00 |
|
| RC218385L4 | Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), mGFP tagged |
CNY 14,440.00 |
|
| SC303356 | IRS4 (untagged)-Human insulin receptor substrate 4 (IRS4) |
CNY 8,760.00 |
