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IRS4 (NM_003604) Human Tagged Lenti ORF Clone
CAT＃: RC218385L1
- LentiORF®
Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), Myc-DDK-tagged
"NM_003604" in other vectors (6)
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CNY 11,152.00
| Cited in 1 publication. |
Product images
CNY 600.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | CHNG9; IRS-4; PY160 |
| Vector | pLenti-C-Myc-DDK |
| E. coli Selection | Chloramphenicol (34 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC218385).
|
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_003604 |
| ORF Size | 3771 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_003604.1 |
| RefSeq Size | 3939 bp |
| RefSeq ORF | 3774 bp |
| Locus ID | 8471 |
| UniProt ID | O14654 |
| Protein Families | Druggable Genome |
| Protein Pathways | Adipocytokine signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Type II diabetes mellitus |
| MW | 133.6 kDa |
| Gene Summary | IRS4 encodes the insulin receptor substrate 4, a cytoplasmic protein that contains many potential tyrosine and serine/threonine phosphorylation sites. Tyrosine-phosphorylated IRS4 protein has been shown to associate with cytoplasmic signalling molecules that contain SH2 domains. The IRS4 protein is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation.. [provided by RefSeq, Jul 2008] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
,Weischenfeldt, J;Dubash, T;Drainas, AP;Mardin, BR;Chen, Y;Stütz, AM;Waszak, SM;Bosco, G;Halvorsen, AR;Raeder, B;Efthymiopoulos, T;Erkek, S;Siegl, C;Brenner, H;Brustugun, OT;Dieter, SM;Northcott, PA;Petersen, I;Pfister, SM;Schneider, M;Solberg, SK;Thunissen, E;Weichert, W;Zichner, T;Thomas, R;Peifer, M;Helland, A;Ball, CR;Jechlinger, M;Sotillo, R;Glimm, H;Korbel, JO;,
Nat. Genet.
,PubMed ID 27869826
[IRS4]
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Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC218385 | IRS4 (Myc-DDK-tagged)-Human insulin receptor substrate 4 (IRS4) |
CNY 8,752.00 |
|
| RC218385L2 | Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), mGFP tagged |
CNY 14,440.00 |
|
| RC218385L3 | Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), Myc-DDK-tagged |
CNY 14,440.00 |
|
| RC218385L4 | Lenti ORF clone of Human insulin receptor substrate 4 (IRS4), mGFP tagged |
CNY 14,440.00 |
|
| RG218385 | IRS4 (tGFP-tagged) - Human insulin receptor substrate 4 (IRS4) |
CNY 10,352.00 |
|
| SC303356 | IRS4 (untagged)-Human insulin receptor substrate 4 (IRS4) |
CNY 8,760.00 |
