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ADAMTS5 (NM_007038) Human Tagged ORF Clone
CAT＃: RG210834
- TrueORF®
ADAMTS5 (tGFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5)
ORF Plasmid: DDK
"NM_007038" in other vectors (6)
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CNY 4,370.00
Product images
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | ADAM-TS 5; ADAM-TS5; ADAM-TS 11; ADAMTS-5; ADAMTS-11; ADAMTS11; ADMP-2 |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RG210834 representing NM_007038
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCTGCTCGGGTGGGCGTCCCTGCTGCTGTGCGCGTTCCGCCTGCCCCTGGCCGCGGTCGGCCCCGCCG CGACACCTGCCCAGGATAAAGCCGGGCAGCCTCCGACTGCTGCAGCAGCCGCCCAGCCCCGCCGGCGGCA GGGGGAGGAGGTGCAGGAGCGAGCCGAGCCTCCCGGCCACCCGCACCCCCTGGCGCAGCGGCGCAGGAGC AAGGGGCTGGTGCAGAACATCGACCAACTCTACTCCGGCGGCGGCAAGGTGGGCTACCTCGTCTACGCGG GCGGCCGGAGGTTCCTCTTGGACCTGGAGCGAGATGGTTCGGTGGGCATTGCTGGCTTCGTGCCCGCAGG AGGCGGGACGAGTGCGCCCTGGCGCCACCGGAGCCACTGCTTCTATCGGGGCACAGTGGACGCTAGTCCC CGCTCTCTGGCTGTCTTTGACCTCTGTGGGGGTCTCGACGGCTTCTTCGCGGTCAAGCACGCGCGCTACA CCCTAAAGCCACTGCTGCGCGGACCCTGGGCGGAGGAAGAAAAGGGGCGCGTGTACGGGGATGGGTCCGC ACGGATCCTGCACGTCTACACCCGCGAGGGCTTCAGCTTCGAGGCCCTGCCGCCGCGCGCCAGCTGCGAA ACCCCCGCGTCCACACCGGAGGCCCACGAGCATGCTCCGGCGCACAGCAACCCGAGCGGACGCGCAGCAC TGGCCTCGCAGCTCTTGGACCAGTCCGCTCTCTCGCCCGCTGGGGGCTCAGGACCGCAGACGTGGTGGCG GCGGCGGCGCCGCTCCATCTCCCGGGCCCGCCAGGTGGAGCTGCTTCTGGTGGCTGACGCGTCCATGGCG CGGTTGTATGGCCGGGGCCTGCAGCATTACCTGCTGACCCTGGCCTCCATCGCCAATAGGCTGTACAGCC ATGCTAGCATCGAGAACCACATCCGCCTGGCCGTGGTGAAGGTGGTGGTGCTAGGCGACAAGGACAAGAG CCTGGAAGTGAGCAAGAACGCTGCCACCACACTCAAGAACTTTTGCAAGTGGCAGCACCAACACAACCAG CTGGGAGATGACCATGAGGAGCACTACGATGCAGCTATCCTGTTTACTCGGGAGGATTTATGTGGGCATC ATTCATGTGACACCCTGGGAATGGCAGACGTTGGGACCATATGTTCTCCAGAGCGCAGCTGTGCTGTGAT TGAAGACGATGGCCTCCACGCAGCCTTCACTGTGGCTCACGAAATCGGACATTTACTTGGCCTCTCCCAT GACGATTCCAAATTCTGTGAAGAGACCTTTGGTTCCACAGAAGATAAGCGCTTAATGTCTTCCATCCTTA CCAGCATTGATGCATCTAAGCCCTGGTCCAAATGCACTTCAGCCACCATCACAGAATTCCTGGATGATGG CCATGGTAACTGTTTGCTGGACCTACCACGAAAGCAGATCCTGGGCCCCGAAGAACTCCCAGGACAGACC TACGATGCCACCCAGCAGTGCAACCTGACATTCGGGCCTGAGTACTCCGTGTGTCCCGGCATGGATGTCT GTGCTCGCCTGTGGTGTGCTGTGGTACGCCAGGGCCAGATGGTCTGTCTGACCAAGAAGCTGCCTGCGGT GGAAGGGACGCCTTGTGGAAAGGGGAGAATCTGCCTGCAGGGCAAATGTGTGGACAAAACCAAGAAAAAA TATTATTCAACGTCAAGCCATGGCAACTGGGGATCTTGGGGATCCTGGGGCCAGTGTTCTCGCTCATGTG GAGGAGGAGTGCAGTTTGCCTATCGTCACTGTAATAACCCTGCTCCCAGAAACAACGGACGCTACTGCAC AGGGAAGAGGGCCATCTACCGCTCCTGCAGTCTCATGCCCTGCCCACCCAATGGTAAATCATTTCGTCAT GAACAGTGTGAGGCCAAAAATGGCTATCAGTCTGATGCAAAAGGAGTCAAAACTTTTGTGGAATGGGTTC CCAAATATGCAGGTGTCCTGCCAGCGGATGTGTGCAAGCTGACCTGCAGAGCCAAGGGCACTGGCTACTA TGTGGTATTTTCTCCAAAGGTGACCGATGGCACTGAATGTAGGCCGTACAGTAATTCCGTCTGCGTCCGG GGGAAGTGTGTGAGAACTGGCTGTGACGGCATCATTGGCTCAAAGCTGCAGTATGACAAGTGCGGAGTAT GTGGAGGAGACAACTCCAGCTGTACAAAGATTGTTGGAACCTTTAATAAGAAAAGTAAGGGTTACACTGA CGTGGTGAGGATTCCTGAAGGGGCAACCCACATAAAAGTTCGACAGTTCAAAGCCAAAGACCAGACTAGA TTCACTGCCTATTTAGCCCTGAAAAAGAAAAACGGTGAGTACCTTATCAATGGAAAGTACATGATCTCCA CTTCAGAGACTATCATTGACATCAATGGAACAGTCATGAACTATAGCGGTTGGAGCCACAGGGATGACTT CCTGCATGGCATGGGCTACTCTGCCACGAAGGAAATTCTAATAGTGCAGATTCTTGCAACAGACCCCACT AAACCATTAGATGTCCGTTATAGCTTTTTTGTTCCCAAGAAGTCCACTCCAAAAGTAAACTCTGTCACTA GTCATGGCAGCAATAAAGTGGGATCACACACTTCGCAGCCGCAGTGGGTCACGGGCCCATGGCTCGCCTG CTCTAGGACCTGTGACACAGGTTGGCACACCAGAACGGTGCAGTGCCAGGATGGAAACCGGAAGTTAGCA AAAGGATGTCCTCTCTCCCAAAGGCCTTCTGCGTTTAAGCAATGCTTGTTGAAGAAATGT AGCGGACCGACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >RG210834 representing NM_007038
Red=Cloning site Green=Tags(s) MLLGWASLLLCAFRLPLAAVGPAATPAQDKAGQPPTAAAAAQPRRRQGEEVQERAEPPGHPHPLAQRRRS KGLVQNIDQLYSGGGKVGYLVYAGGRRFLLDLERDGSVGIAGFVPAGGGTSAPWRHRSHCFYRGTVDASP RSLAVFDLCGGLDGFFAVKHARYTLKPLLRGPWAEEEKGRVYGDGSARILHVYTREGFSFEALPPRASCE TPASTPEAHEHAPAHSNPSGRAALASQLLDQSALSPAGGSGPQTWWRRRRRSISRARQVELLLVADASMA RLYGRGLQHYLLTLASIANRLYSHASIENHIRLAVVKVVVLGDKDKSLEVSKNAATTLKNFCKWQHQHNQ LGDDHEEHYDAAILFTREDLCGHHSCDTLGMADVGTICSPERSCAVIEDDGLHAAFTVAHEIGHLLGLSH DDSKFCEETFGSTEDKRLMSSILTSIDASKPWSKCTSATITEFLDDGHGNCLLDLPRKQILGPEELPGQT YDATQQCNLTFGPEYSVCPGMDVCARLWCAVVRQGQMVCLTKKLPAVEGTPCGKGRICLQGKCVDKTKKK YYSTSSHGNWGSWGSWGQCSRSCGGGVQFAYRHCNNPAPRNNGRYCTGKRAIYRSCSLMPCPPNGKSFRH EQCEAKNGYQSDAKGVKTFVEWVPKYAGVLPADVCKLTCRAKGTGYYVVFSPKVTDGTECRPYSNSVCVR GKCVRTGCDGIIGSKLQYDKCGVCGGDNSSCTKIVGTFNKKSKGYTDVVRIPEGATHIKVRQFKAKDQTR FTAYLALKKKNGEYLINGKYMISTSETIIDINGTVMNYSGWSHRDDFLHGMGYSATKEILIVQILATDPT KPLDVRYSFFVPKKSTPKVNSVTSHGSNKVGSHTSQPQWVTGPWLACSRTCDTGWHTRTVQCQDGNRKLA KGCPLSQRPSAFKQCLLKKC SGPTRTRRLE - GFP Tag - V |
| Restriction Sites |
SgfI-RsrII
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_007038 |
| ORF Size | 2790 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_007038.2, NP_008969.1 |
| RefSeq Size | 9046 bp |
| RefSeq ORF | 2793 bp |
| Locus ID | 11096 |
| UniProt ID | Q9UNA0 |
| Domains | tsp_1, Reprolysin, ACR |
| Protein Families | Druggable Genome, Protease, Secreted Protein |
| Gene Summary | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. [provided by RefSeq, Feb 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210834 | ADAMTS5 (Myc-DDK-tagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) |
CNY 3,990.00 |
|
| RC210834L1 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210834L2 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), mGFP tagged |
CNY 5,890.00 |
|
| RC210834L3 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC210834L4 | Lenti ORF clone of Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5), mGFP tagged |
CNY 5,890.00 |
|
| SC115752 | ADAMTS5 (untagged)-Human ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) |
CNY 6,816.00 |
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