LRP2 (NM_004525) Human Tagged ORF Clone

Specifications

Product Data
Type	Human Tagged ORF Clone
Tag	Myc-DDK
Synonyms	DBS; GP330; LRP-2
Vector	pCMV6-Entry
E. coli Selection	Kanamycin (25 ug/mL)
Mammalian Cell Selection	Neomycin
Sequence Data	ORF Nucleotide Sequence (showhide) >RC213707 representing NM_004525. Blue=ORF Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGATCGCGGGCCGGCAGCAGTGGCGTGCACGCTGCTCCTGGCTCTCGTCGCCTGCCTAGCCCCGGCC AGTGGCCAAGAATGTGACAGTGCGCATTTTCGCTGTGGAAGTGGGCATTGCATCCCTGCAGACTGGAGG TGTGATGGGACCAAAGACTGTTCAGATGACGCGGATGAAATTGGCTGCGCTGTTGTGACCTGCCAGCAG GGCTATTTCAAGTGCCAGAGTGAGGGACAATGCATCCCCAGCTCCTGGGTGTGTGACCAAGATCAAGAC TGTGATGATGGCTCAGATGAACGTCAAGATTGCTCACAAAGTACATGCTCAAGTCATCAGATAACATGC TCCAATGGTCAGTGTATCCCAAGTGAATACAGGTGCGACCACGTCAGAGACTGCCCCGATGGAGCTGAT GAGAATGACTGCCAGTACCCAACATGTGAGCAGCTTACTTGTGACAATGGGGCCTGCTATAACACCAGT CAGAAGTGTGATTGGAAAGTTGATTGCAGGGACTCCTCAGATGAAATCAACTGCACTGAGATATGCTTG CACAATGAGTTTTCATGTGGCAATGGAGAGTGTATCCCTCGTGCTTATGTCTGTGACCATGACAATGAT TGCCAAGACGGCAGTGATGAACATGCTTGCAACTATCCGACCTGCGGTGGTTACCAGTTCACTTGCCCC AGTGGCCGATGCATTTATCAAAACTGGGTTTGTGATGGAGAAGATGACTGTAAAGATAATGGAGATGAA GATGGATGTGAAAGCGGTCCTCATGATGTTCATAAATGTTCCCCAAGAGAATGGTCTTGCCCAGAGTCG GGACGATGCATCTCCATTTATAAAGTTTGTGATGGGATTTTAGATTGCCCAGGAAGAGAAGATGAAAAC AACACTAGTACCGGAAAATACTGTAGTATGACTCTGTGCTCTGCCTTGAACTGCCAGTACCAGTGCCAT GAGACGCCGTATGGAGGAGCGTGTTTTTGTCCCCCAGGTTATATCATCAACCACAATGACAGCCGTACC TGTGTTGAGTTTGATGATTGCCAGATATGGGGAATTTGTGACCAGAAGTGTGAAAGCCGACCTGGCCGT CACCTGTGCCACTGTGAAGAAGGGTATATCTTGGAGCGTGGACAGTATTGCAAAGCTAATGATTCCTTT GGCGAGGCCTCCATTATCTTCTCCAATGGTCGGGATTTGTTAATTGGTGATATTCATGGAAGGAGCTTC CGGATCCTAGTGGAGTCTCAGAATCGTGGAGTGGCCGTGGGTGTGGCTTTCCACTATCACCTGCAAAGA GTTTTTTGGACAGACACCGTGCAAAATAAGGTTTTTTCAGTTGACATTAATGGTTTAAATATCCAAGAG GTTCTCAATGTTTCTGTTGAAACCCCAGAGAACCTGGCTGTGGACTGGGTTAATAATAAAATCTATCTA GTGGAAACCAAGGTCAACCGCATAGATATGGTAAATTTGGATGGAAGCTATCGGGTTACCCTTATAACT GAAAACTTGGGGCATCCTAGAGGAATTGCCGTGGACCCAACTGTTGGTTATTTATTTTTCTCAGATTGG GAGAGCCTTTCTGGGGAACCTAAGCTGGAAAGGGCATTCATGGATGGCAGCAACCGTAAAGACTTGGTG AAAACAAAGCTGGGATGGCCTGCTGGGGTAACTCTGGATATGATATCGAAGCGTGTTTACTGGGTTGAC TCTCGGTTTGATTACATTGAAACTGTAACTTATGATGGAATTCAAAGGAAGACTGTAGTTCATGGAGGC TCCCTCATTCCTCATCCCTTTGGAGTAAGCTTATTTGAAGGTCAGGTGTTCTTTACAGATTGGACAAAG ATGGCCGTGCTGAAGGCAAACAAGTTCACAGAGACCAACCCACAAGTGTACTACCAGGCTTCCCTGAGG CCCTATGGAGTGACTGTTTACCATTCCCTCAGACAGCCCTATGCTACCAATCCGTGTAAAGATAACAAT GGGGGCTGTGAGCAGGTCTGTGTTCTCAGCCACAGAACAGATAATGATGGTTTGGGTTTCCGTTGCAAG TGCACATTCGGCTTCCAACTGGATACAGATGAGCGCCACTGCATTGCTGTTCAGAATTTCCTCATTTTT TCATCCCAAGTTGCTATTCGTGGGATCCCGTTCACCTTGTCTACCCAGGAAGATGTCATGGTTCCAGTT TCGGGGAATCCTTCTTTCTTTGTCGGGATTGATTTTGACGCCCAGGACAGCACTATCTTTTTTTCAGAT ATGTCAAAACACATGATTTTTAAGCAAAAGATTGATGGCACAGGAAGAGAAATTCTCGCAGCTAACAGG GTGGAAAATGTTGAAAGTTTGGCTTTTGATTGGATTTCAAAGAATCTCTATTGGACAGACTCTCATTAC AAGAGTATCAGTGTCATGAGGCTAGCTGATAAAACGAGACGCACGGTAGTTCAGTATTTAAATAACCCA CGGTCGGTGGTAGTTCATCCTTTTGCCGGGTATCTATTCTTCACTGATTGGTTCCGTCCTGCTAAAATT ATGAGAGCATGGAGTGACGGATCTCACCTCTTGCCTGTAATAAACACTACTCTTGGATGGCCCAATGGC TTGGCCATCGATTGGGCTGCTTCACGATTGTACTGGGTAGATGCCTATTTTGATAAAATTGAGCACAGC ACCTTTGATGGTTTAGACAGAAGAAGACTGGGCCATATAGAGCAGATGACACATCCGTTTGGACTTGCC ATCTTTGGAGAGCATTTATTTTTTACTGACTGGAGACTGGGTGCCATTATTCGAGTCAGGAAAGCAGAT GGTGGAGAAATGACAGTTATCCGAAGTGGCATTGCTTACATACTGCATTTGAAATCGTATGATGTCAAC ATCCAGACTGGTTCTAACGCCTGTAATCAACCCACGCATCCTAACGGTGACTGCAGCCACTTCTGCTTC CCGGTGCCAAATTTCCAGCGAGTGTGTGGGTGCCCTTATGGAATGAGGCTGGCTTCCAATCACTTGACA TGCGAGGGGGACCCAACAAATGAACCACCCACGGAGCAGTGTGGCTTATTTTCCTTCCCCTGTAAAAAT GGCAGATGTGTGCCCAATTACTATCTCTGTGATGGAGTCGATGATTGTCATGATAACAGTGATGAGCAA CTATGTGGCACACTTAATAATACCTGTTCATCTTCGGCGTTCACCTGTGGCCATGGGGAGTGCATTCCT GCACACTGGCGCTGTGACAAACGCAACGACTGTGTGGATGGCAGTGATGAGCACAACTGCCCCACCCAC GCACCTGCTTCCTGCCTTGACACCCAATACACCTGTGATAATCACCAGTGTATCTCAAAGAACTGGGTC TGTGACACAGACAATGATTGTGGGGATGGATCTGATGAAAAGAACTGCAATTCGACAGAGACATGCCAA CCTAGTCAGTTTAATTGCCCCAATCATCGATGTATTGACCTATCGTTTGTCTGTGATGGTGACAAGGAT TGTGTTGATGGATCTGATGAGGTTGGTTGTGTATTAAACTGTACTGCTTCTCAATTCAAGTGTGCCAGT GGGGATAAATGTATTGGCGTCACAAATCGTTGTGATGGTGTTTTTGATTGCAGTGACAACTCGGATGAA GCGGGCTGTCCAACCAGGCCTCCTGGTATGTGCCACTCAGATGAATTTCAGTGCCAAGAAGATGGTATC TGCATCCCGAACTTCTGGGAATGTGATGGGCATCCAGACTGCCTCTATGGATCTGATGAGCACAATGCC TGTGTCCCCAAGACTTGCCCTTCATCATATTTCCACTGTGACAACGGAAACTGCATCCACAGGGCATGG CTCTGTGATCGGGACAATGACTGCGGGGATATGAGTGATGAGAAGGACTGCCCTACTCAGCCCTTTCGC TGTCCTAGTTGGCAATGGCAGTGTCTTGGCCATAACATCTGTGTGAATCTGAGTGTAGTGTGTGATGGC ATCTTTGACTGCCCCAATGGGACAGATGAGTCCCCACTTTGCAATGGGAACAGCTGCTCAGATTTCAAT GGTGGTTGTACTCACGAGTGTGTTCAAGAGCCCTTTGGGGCTAAATGCCTATGTCCATTGGGATTCTTA CTTGCCAATGATTCTAAGACCTGTGAAGACATAGATGAATGTGATATTCTAGGCTCTTGTAGCCAGCAC TGTTACAATATGAGAGGTTCTTTCCGGTGCTCGTGTGATACAGGCTACATGTTAGAAAGTGATGGGAGG ACTTGCAAAGTTACAGCATCTGAGAGTCTGCTGTTACTTGTGGCAAGTCAGAACAAAATTATTGCCGAC AGTGTCACCTCCCAGGTCCACAATATCTATTCATTGGTCGAGAATGGTTCTTACATTGTAGCTGTTGAT TTTGATTCAATTAGTGGTCGTATCTTTTGGTCTGATGCAACTCAGGGTAAAACCTGGAGTGCGTTTCAA AATGGAACGGACAGAAGAGTGGTATTTGACAGTAGCATCATCTTGACTGAAACTATTGCAATAGATTGG GTAGGTCGTAATCTTTACTGGACAGACTATGCTCTGGAAACAATTGAAGTCTCCAAAATTGATGGGAGC CACAGGACTGTGCTGATTAGTAAAAACCTAACAAATCCAAGAGGACTAGCATTAGATCCCAGAATGAAT GAGCATCTACTGTTCTGGTCTGACTGGGGCCACCACCCTCGCATCGAGCGAGCCAGCATGGACGGCAGC ATGCGCACTGTCATTGTCCAGGACAAGATCTTCTGGCCCTGCGGCTTAACTATTGACTACCCCAACAGA CTGCTCTACTTCATGGACTCCTATCTTGATTACATGGACTTTTGTGATTATAATGGACACCATCGGAGA CAGGTGATAGCCAGTGATTTGATTATACGGCACCCCTATGCCCTAACTCTCTTTGAAGACTCTGTGTAC TGGACTGACCGTGCTACTCGTCGGGTTATGCGAGCCAACAAGTGGCATGGAGGGAACCAGTCAGTTGTA ATGTATAATATTCAATGGCCCCTTGGGATTGTTGCGGTTCATCCTTCGAAACAACCAAATTCCGTGAAT CCATGTGCCTTTTCCCGCTGCAGCCATCTCTGCCTGCTTTCCTCACAGGGGCCTCATTTTTACTCCTGT GTTTGTCCTTCAGGATGGAGTCTGTCTCCTGATCTCCTGAATTGCTTGAGAGATGATCAACCTTTCTTA ATAACTGTAAGGCAACATATAATTTTTGGAATCTCCCTTAATCCTGAGGTGAAGAGCAATGATGCTATG GTCCCCATAGCAGGGATACAGAATGGTTTAGATGTTGAATTTGATGATGCTGAGCAATACATCTATTGG GTTGAAAATCCAGGTGAAATTCACAGAGTGAAGACAGATGGCACCAACAGGACAGTATTTGCTTCTATA TCTATGGTGGGGCCTTCTATGAACCTGGCCTTAGATTGGATTTCAAGAAACCTTTATTCTACCAATCCT AGAACTCAGTCAATCGAGGTTTTGACACTCCACGGAGATATCAGATACAGAAAAACATTGATTGCCAAT GATGGGACAGCTCTTGGAGTTGGCTTTCCAATTGGCATAACTGTTGATCCTGCTCGTGGGAAGCTGTAC TGGTCAGACCAAGGAACTGACAGTGGGGTTCCTGCCAAGATCGCCAGTGCTAACATGGATGGCACATCT GTGAAAACTCTCTTTACTGGGAACCTCGAACACCTGGAGTGTGTCACTCTTGACATCGAAGAGCAGAAA CTCTACTGGGCAGTCACTGGAAGAGGAGTGATTGAAAGAGGAAACGTGGATGGAACAGATCGAATGATC CTGGTACACCAGCTTTCCCACCCCTGGGGAATTGCAGTCCATGATTCTTTCCTTTATTATACTGATGAA CAGTATGAGGTCATTGAAAGAGTTGATAAGGCCACTGGGGCCAACAAAATAGTCTTGAGAGATAATGTT CCAAATCTGAGGGGTCTTCAAGTTTATCACAGACGCAATGCCGCCGAATCCTCAAATGGCTGTAGCAAC AACATGAATGCCTGTCAGCAGATTTGCCTGCCTGTACCAGGAGGATTGTTTTCCTGCGCCTGTGCCACT GGATTTAAACTCAATCCTGATAATCGGTCCTGCTCTCCATATAACTCTTTCATTGTTGTTTCAATGCTG TCTGCAATCAGAGGCTTTAGCTTGGAATTGTCAGATCATTCAGAAACCATGGTGCCGGTGGCAGGCCAA GGACGAAACGCACTGCATGTGGATGTGGATGTGTCCTCTGGCTTTATTTATTGGTGTGATTTTAGCAGC TCAGTGGCATCTGATAATGCGATCCGTAGAATTAAACCAGATGGATCTTCTCTGATGAACATTGTGACA CATGGAATAGGAGAAAATGGAGTCCGGGGTATTGCAGTGGATTGGGTAGCAGGAAATCTTTATTTCACC AATGCCTTTGTTTCTGAAACACTGATAGAAGTTCTGCGGATCAATACTACTTACCGCCGTGTTCTTCTT AAAGTCACAGTGGACATGCCTAGGCATATTGTTGTAGATCCCAAGAACAGATACCTCTTCTGGGCTGAC TATGGGCAGAGACCAAAGATTGAGCGTTCTTTCCTTGACTGTACCAATCGAACAGTGCTTGTGTCAGAG GGCATTGTCACACCACGGGGCTTGGCAGTGGACCGAAGTGATGGCTACGTTTATTGGGTTGATGATTCT TTAGATATAATTGCAAGGATTCGTATCAATGGAGAGAACTCTGAAGTGATTCGTTATGGCAGTCGTTAC CCAACTCCTTATGGCATCACTGTTTTTGAAAATTCTATCATATGGGTAGATAGGAATTTGAAAAAGATC TTCCAAGCCAGCAAGGAACCAGAGAACACAGAGCCACCCACAGTGATAAGAGACAATATCAACTGGCTA AGAGATGTGACCATCTTTGACAAGCAAGTCCAGCCCCGGTCACCAGCAGAGGTCAACAACAACCCTTGC TTGGAAAACAATGGTGGGTGCTCTCATCTCTGCTTTGCTCTGCCTGGATTGCACACCCCAAAATGTGAC TGTGCCTTTGGGACCCTGCAAAGTGATGGCAAGAATTGTGCCATTTCAACAGAAAATTTCCTCATCTTT GCCTTGTCTAATTCCTTGAGAAGCTTACACTTGGACCCTGAAAACCATAGCCCACCTTTCCAAACAATA AATGTGGAAAGAACTGTCATGTCTCTAGACTATGACAGTGTAAGTGATAGAATCTACTTCACACAAAAT TTAGCCTCTGGAGTTGGACAGATTTCCTATGCCACCCTGTCTTCAGGGATCCATACTCCAACTGTCATT GCTTCAGGTATAGGGACTGCTGATGGCATTGCCTTTGACTGGATTACTAGAAGAATTTATTACAGTGAC TACCTCAACCAGATGATTAATTCCATGGCTGAAGATGGGTCTAACCGCACTGTGATAGCCCGCGTTCCA AAACCAAGAGCAATTGTGTTAGATCCCTGCCAAGGGTACCTGTACTGGGCTGACTGGGATACACATGCC AAAATCGAGAGAGCCACATTGGGAGGAAACTTCCGCGTACCCATTGTGAACAGCAGTCTGGTCATGCCC AGTGGGCTGACTCTGGACTATGAAGAGGACCTTCTCTACTGGGTGGATGCTAGTCTGCAGAGGATTGAA CGCAGCACTCTGACGGGCGTGGATCGTGAAGTCATTGTCAATGCAGCCGTTCATGCTTTTGGCTTGACT CTCTATGGCCAGTATATTTACTGGACTGACTTGTACACACAAAGAATTTACCGAGCTAACAAATATGAC GGGTCAGGTCAGATTGCAATGACCACAAATTTGCTCTCCCAGCCCAGGGGAATCAACACTGTTGTGAAG AACCAGAAACAACAGTGTAACAATCCTTGTGAACAGTTTAATGGGGGCTGCAGCCATATCTGTGCACCA GGTCCAAATGGTGCCGAGTGCCAGTGTCCACATGAGGGCAACTGGTATTTGGCCAACAACAGGAAGCAC TGCATTGTGGACAATGGTGAACGATGTGGTGCATCTTCCTTCACCTGCTCCAATGGGCGCTGCATCTCG GAAGAGTGGAAGTGTGATAATGACAACGACTGTGGGGATGGCAGTGATGAGATGGAAAGTGTCTGTGCA CTTCACACCTGCTCACCGACAGCCTTCACCTGTGCCAATGGGCGATGTGTCCAATACTCTTACCGCTGT GATTACTACAATGACTGTGGTGATGGCAGTGATGAGGCAGGGTGCCTGTTCAGGGACTGCAATGCCACC ACGGAGTTTATGTGCAATAACAGAAGGTGCATACCTCGTGAGTTTATCTGCAATGGTGTAGACAACTGC CATGATAATAACACTTCAGATGAGAAAAATTGCCCTGATCGCACTTGCCAGTCTGGATACACAAAATGT CATAATTCAAATATTTGTATTCCTCGCGTTTATTTGTGTGACGGAGACAATGACTGTGGAGATAACAGT GATGAAAACCCTACTTATTGCACCACTCACACGTGCAGCAGCAGTGAGTTCCAATGCGCATCTGGGCGC TGTATTCCTCAACATTGGTATTGTGATCAAGAAACAGATTGTTTTGATGCCTCTGATGAACCTGCCTCT TGTGGTCACTCTGAGCGAACATGCCTAGCTGATGAGTTCAAGTGTGATGGTGGGAGGTGCATCCCAAGC GAATGGATCTGTGACGGTGATAATGACTGTGGGGATATGAGTGACGAGGATAAAAGGCACCAGTGTCAG AATCAAAACTGCTCGGATTCCGAGTTTCTCTGTGTAAATGACAGACCTCCGGACAGGAGGTGCATTCCC CAGTCTTGGGTCTGTGATGGCGATGTGGATTGTACTGACGGCTACGATGAGAATCAGAATTGCACCAGG AGAACTTGCTCTGAAAATGAATTCACCTGTGGTTACGGACTGTGTATCCCAAAGATATTCAGGTGTGAC CGGCACAATGACTGTGGTGACTATAGCGACGAGAGGGGCTGCTTATACCAGACTTGCCAACAGAATCAG TTTACCTGTCAGAACGGGCGCTGCATTAGTAAAACCTTCGTCTGTGATGAGGATAATGACTGTGGAGAC GGATCTGATGAGCTGATGCACCTGTGCCACACCCCAGAACCCACGTGTCCACCTCACGAGTTCAAGTGT GACAATGGGCGCTGCATCGAGATGATGAAACTCTGCAACCACCTAGATGACTGTTTGGACAACAGCGAT GAGAAAGGCTGTGGCATTAATGAATGCCATGACCCTTCAATCAGTGGCTGCGATCACAACTGCACAGAC ACCTTAACCAGTTTCTATTGTTCCTGTCGTCCTGGTTACAAGCTCATGTCTGACAAGCGGACTTGTGTT GATATTGATGAATGCACAGAGATGCCTTTTGTCTGTAGCCAGAAGTGTGAGAATGTAATAGGCTCCTAC ATCTGTAAGTGTGCCCCAGGCTACCTCCGAGAACCAGATGGAAAGACCTGCCGGCAAAACAGTAACATC GAACCCTATCTCATTTTTAGCAACCGTTACTATTTGAGAAATTTAACTATAGATGGCTATTTTTACTCC CTCATCTTGGAAGGACTGGACAATGTTGTGGCATTAGATTTTGACCGAGTAGAGAAGAGATTGTATTGG ATTGATACACAGAGGCAAGTCATTGAGAGAATGTTTCTGAATAAGACAAACAAGGAGACAATCATAAAC CACAGACTACCAGCTGCAGAAAGTCTGGCTGTAGACTGGGTTTCCAGAAAGCTCTACTGGTTGGATGCC CGCCTGGATGGCCTCTTTGTCTCTGACCTCAATGGTGGACACCGCCGCATGCTGGCCCAGCACTGTGTG GATGCCAACAACACCTTCTGCTTTGATAATCCCAGAGGACTTGCCCTTCACCCTCAATATGGGTACCTC TACTGGGCAGACTGGGGTCACCGCGCATACATTGGGAGAGTAGGCATGGATGGAACCAACAAGTCTGTG ATAATCTCCACCAAGTTAGAGTGGCCTAATGGCATCACCATTGATTACACCAATGATCTACTCTACTGG GCAGATGCCCACCTGGGTTACATAGAGTACTCTGATTTGGAGGGCCACCATCGACACACGGTGTATGAT GGGGCACTGCCTCACCCTTTCGCTATTACCATTTTTGAAGACACTATTTATTGGACAGATTGGAATACA AGGACAGTGGAAAAGGGAAACAAATATGATGGATCAAATAGACAGACACTGGTGAACACAACACACAGA CCATTTGACATCCATGTGTACCATCCATATAGGCAGCCCATTGTGAGCAATCCCTGTGGTACCAACAAT GGTGGCTGTTCTCATCTCTGCCTCATCAAGCCAGGAGGAAAAGGGTTCACTTGCGAGTGTCCAGATGAC TTCCGCACCCTTCAGCTGAGTGGCAGCACCTACTGCATGCCCATGTGCTCCAGCACCCAGTTCCTGTGC GCTAACAATGAAAAGTGCATTCCTATCTGGTGGAAATGTGATGGACAGAAAGACTGCTCAGATGGCTCT GATGAACTGGCCCTTTGCCCGCAGCGCTTCTGCCGACTGGGACAGTTCCAGTGCAGTGACGGCAACTGC ACCAGCCCGCAGACTTTATGCAATGCTCACCAAAATTGCCCTGATGGGTCTGATGAAGACCGTCTTCTT TGTGAGAATCACCACTGTGACTCCAATGAATGGCAGTGCGCCAACAAACGTTGCATCCCAGAATCCTGG CAGTGTGACACATTTAACGACTGTGAGGATAACTCAGATGAAGACAGTTCCCACTGTGCCAGCAGGACC TGCCGGCCGGGCCAGTTTCGGTGTGCTAATGGCCGCTGCATCCCGCAGGCCTGGAAGTGTGATGTGGAT AATGATTGTGGAGACCACTCGGATGAGCCCATTGAAGAATGCATGAGCTCTGCCCATCTCTGTGACAAC TTCACAGAATTCAGCTGCAAAACAAATTACCGCTGCATCCCAAAGTGGGCCGTGTGCAATGGTGTAGAT GACTGCAGGGACAACAGTGATGAGCAAGGCTGTGAGGAGAGGACATGCCATCCTGTGGGGGATTTCCGC TGTAAAAATCACCACTGCATCCCTCTTCGTTGGCAGTGTGATGGGCAAAATGACTGTGGAGATAACTCA GATGAGGAAAACTGTGCTCCCCGGGAGTGCACAGAGAGCGAGTTTCGATGTGTCAATCAGCAGTGCATT CCCTCGCGATGGATCTGTGACCATTACAACGACTGTGGGGACAACTCAGATGAACGGGACTGTGAGATG AGGACCTGCCATCCTGAATATTTTCAGTGTACAAGTGGACATTGTGTACACAGTGAACTGAAATGCGAT GGATCCGCTGACTGTTTGGATGCGTCTGATGAAGCTGATTGTCCCACACGCTTTCCTGATGGTGCATAC TGCCAGGCTACTATGTTCGAATGCAAAAACCATGTTTGTATCCCGCCATATTGGAAATGTGATGGCGAT GATGACTGTGGCGATGGTTCAGATGAAGAACTTCACCTGTGCTTGGATGTTCCCTGTAATTCACCAAAC CGTTTCCGGTGTGACAACAATCGCTGCATTTATAGTCATGAGGTGTGCAATGGTGTGGATGACTGTGGA GATGGAACTGATGAGACAGAGGAGCACTGTAGAAAACCGACCCCTAAACCTTGTACAGAATATGAATAT AAGTGTGGCAATGGGCATTGCATTCCACATGACAATGTGTGTGATGATGCCGATGACTGTGGTGACTGG TCCGATGAACTGGGTTGCAATAAAGGAAAAGAAAGAACATGTGCTGAAAATATATGCGAGCAAAATTGT ACCCAATTAAATGAAGGAGGATTTATCTGCTCCTGTACAGCTGGGTTCGAAACCAATGTTTTTGACAGA ACCTCCTGTCTAGATATCAATGAATGTGAACAATTTGGGACTTGTCCCCAGCACTGCAGAAATACCAAA GGAAGTTATGAGTGTGTCTGTGCTGATGGCTTCACGTCTATGAGTGACCGCCCTGGAAAACGATGTGCA GCTGAGGGTAGCTCTCCTTTGTTGCTACTGCCTGACAATGTCCGAATTCGAAAATATAATCTCTCATCT GAGAGGTTCTCAGAGTATCTTCAAGATGAGGAATATATCCAAGCTGTTGATTATGATTGGGATCCCGAG GACATAGGCCTCAGTGTTGTGTATTACACTGTGCGAGGGGAGGGCTCTAGGTTTGGTGCTATCAAACGT GCCTACATCCCCAACTTTGAATCCGGCCGCAATAATCTTGTGCAGGAAGTTGACCTGAAACTGAAATAC GTAATGCAGCCAGATGGAATAGCAGTGGACTGGGTTGGAAGGCATATTTACTGGTCAGATGTCAAGAAT AAACGCATTGAGGTGGCTAAACTTGATGGAAGGTACAGAAAGTGGCTGATTTCCACTGACCTGGACCAA CCAGCTGCTATTGCTGTGAATCCCAAACTAGGGCTTATGTTCTGGACTGACTGGGGAAAGGAACCTAAA CTCGAGTCTGCCTGGATGAATGGAGAGGACCGCAACATCCTGGTTTTCGAGGACCTTGGTTGGCCAACT GGCCTTTCTATCGATTATTTGAACAATGACCGAATCTACTGGAGTGACTTCAAGGAGGACGTTATTGAA ACCATAAAATATGATGGGACTGATAGGAGAGTCATTGCAAAGGAAGCAATGAACCCTTACAGCCTGGAC ATCTTTGAAGACCAGTTATACTGGATATCTAAGGAAAAGGGAGAAGTATGGAAACAAAATAAATTTGGG CAAGGAAAGAAAGAGAAAACGCTGGTAGTGAACCCTTGGCTCACTCAAGTTCGAATCTTTCATCAACTC AGATACAATAAGTCAGTGCCCAACCTTTGCAAACAGATCTGCAGCCACCTCTGCCTTCTGAGACCTGGA GGATACAGCTGTGCCTGTCCCCAAGGCTCCAGCTTTATAGAGGGGAGCACCACTGAGTGTGATGCAGCC ATTGAACTGCCTATCAACCTGCCCCCCCCATGCAGGTGCATGCACGGAGGAAATTGCTATTTTGATGAG ACTGACCTCCCCAAATGCAAGTGTCCTAGCGGCTACACCGGAAAATATTGTGAAATGGCGTTTTCAAAA GGCATCTCTCCAGGAACAACCGCAGTAGCTGTGCTGTTGACAATCCTCTTGATCGTCGTAATTGGAGCT CTGGCAATTGCAGGATTCTTCCACTATAGAAGGACCGGCTCCCTTTTGCCTGCTCTGCCCAAGCTGCCA AGCTTAAGCAGTCTCGTCAAGCCCTCTGAAAATGGGAATGGGGTGACCTTCAGATCAGGGGCAGATCTT AACATGGATATTGGAGTGTCTGGTTTTGGACCTGAGACTGCTATTGACAGGTCAATGGCAATGAGTGAA GACTTTGTCATGGAAATGGGGAAGCAGCCCATAATATTTGAAAACCCAATGTACTCAGCCAGAGACAGT GCTGTCAAAGTGGTTCAGCCAATCCAGGTGACTGTATCTGAAAATGTGGATAATAAGAATTATGGAAGT CCCATAAACCCTTCTGAGATAGTTCCAGAGACAAACCCAACTTCACCAGCTGCTGATGGAACTCAGGTG ACAAAATGGAATCTCTTCAAACGAAAATCTAAACAAACTACCAACTTTGAAAATCCAATCTATGCACAG ATGGAGAACGAGCAAAAGGAAAGTGTTGCTGCGACACCACCTCCATCACCTTCGCTCCCTGCTAAGCCT AAGCCTCCTTCGAGAAGAGACCCAACTCCAACCTATTCTGCAACAGAAGACACTTTTAAAGACACCGCA AATCTTGTTAAAGAAGACTCTGAAGTA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC Protein Sequence (showhide) >Peptide sequence encoded by RC213707 Blue=ORF Red=Cloning site Green=Tag(s) MDRGPAAVACTLLLALVACLAPASGQECDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAVVTCQQ GYFKCQSEGQCIPSSWVCDQDQDCDDGSDERQDCSQSTCSSHQITCSNGQCIPSEYRCDHVRDCPDGAD ENDCQYPTCEQLTCDNGACYNTSQKCDWKVDCRDSSDEINCTEICLHNEFSCGNGECIPRAYVCDHDND CQDGSDEHACNYPTCGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGCESGPHDVHKCSPREWSCPES GRCISIYKVCDGILDCPGREDENNTSTGKYCSMTLCSALNCQYQCHETPYGGACFCPPGYIINHNDSRT CVEFDDCQIWGICDQKCESRPGRHLCHCEEGYILERGQYCKANDSFGEASIIFSNGRDLLIGDIHGRSF RILVESQNRGVAVGVAFHYHLQRVFWTDTVQNKVFSVDINGLNIQEVLNVSVETPENLAVDWVNNKIYL VETKVNRIDMVNLDGSYRVTLITENLGHPRGIAVDPTVGYLFFSDWESLSGEPKLERAFMDGSNRKDLV KTKLGWPAGVTLDMISKRVYWVDSRFDYIETVTYDGIQRKTVVHGGSLIPHPFGVSLFEGQVFFTDWTK MAVLKANKFTETNPQVYYQASLRPYGVTVYHSLRQPYATNPCKDNNGGCEQVCVLSHRTDNDGLGFRCK CTFGFQLDTDERHCIAVQNFLIFSSQVAIRGIPFTLSTQEDVMVPVSGNPSFFVGIDFDAQDSTIFFSD MSKHMIFKQKIDGTGREILAANRVENVESLAFDWISKNLYWTDSHYKSISVMRLADKTRRTVVQYLNNP RSVVVHPFAGYLFFTDWFRPAKIMRAWSDGSHLLPVINTTLGWPNGLAIDWAASRLYWVDAYFDKIEHS TFDGLDRRRLGHIEQMTHPFGLAIFGEHLFFTDWRLGAIIRVRKADGGEMTVIRSGIAYILHLKSYDVN IQTGSNACNQPTHPNGDCSHFCFPVPNFQRVCGCPYGMRLASNHLTCEGDPTNEPPTEQCGLFSFPCKN GRCVPNYYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNCPTH APASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKNCNSTETCQPSQFNCPNHRCIDLSFVCDGDKD CVDGSDEVGCVLNCTASQFKCASGDKCIGVTNRCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGI CIPNFWECDGHPDCLYGSDEHNACVPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDCPTQPFR CPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDESPLCNGNSCSDFNGGCTHECVQEPFGAKCLCPLGFL LANDSKTCEDIDECDILGSCSQHCYNMRGSFRCSCDTGYMLESDGRTCKVTASESLLLLVASQNKIIAD SVTSQVHNIYSLVENGSYIVAVDFDSISGRIFWSDATQGKTWSAFQNGTDRRVVFDSSIILTETIAIDW VGRNLYWTDYALETIEVSKIDGSHRTVLISKNLTNPRGLALDPRMNEHLLFWSDWGHHPRIERASMDGS MRTVIVQDKIFWPCGLTIDYPNRLLYFMDSYLDYMDFCDYNGHHRRQVIASDLIIRHPYALTLFEDSVY WTDRATRRVMRANKWHGGNQSVVMYNIQWPLGIVAVHPSKQPNSVNPCAFSRCSHLCLLSSQGPHFYSC VCPSGWSLSPDLLNCLRDDQPFLITVRQHIIFGISLNPEVKSNDAMVPIAGIQNGLDVEFDDAEQYIYW VENPGEIHRVKTDGTNRTVFASISMVGPSMNLALDWISRNLYSTNPRTQSIEVLTLHGDIRYRKTLIAN DGTALGVGFPIGITVDPARGKLYWSDQGTDSGVPAKIASANMDGTSVKTLFTGNLEHLECVTLDIEEQK LYWAVTGRGVIERGNVDGTDRMILVHQLSHPWGIAVHDSFLYYTDEQYEVIERVDKATGANKIVLRDNV PNLRGLQVYHRRNAAESSNGCSNNMNACQQICLPVPGGLFSCACATGFKLNPDNRSCSPYNSFIVVSML SAIRGFSLELSDHSETMVPVAGQGRNALHVDVDVSSGFIYWCDFSSSVASDNAIRRIKPDGSSLMNIVT HGIGENGVRGIAVDWVAGNLYFTNAFVSETLIEVLRINTTYRRVLLKVTVDMPRHIVVDPKNRYLFWAD YGQRPKIERSFLDCTNRTVLVSEGIVTPRGLAVDRSDGYVYWVDDSLDIIARIRINGENSEVIRYGSRY PTPYGITVFENSIIWVDRNLKKIFQASKEPENTEPPTVIRDNINWLRDVTIFDKQVQPRSPAEVNNNPC LENNGGCSHLCFALPGLHTPKCDCAFGTLQSDGKNCAISTENFLIFALSNSLRSLHLDPENHSPPFQTI NVERTVMSLDYDSVSDRIYFTQNLASGVGQISYATLSSGIHTPTVIASGIGTADGIAFDWITRRIYYSD YLNQMINSMAEDGSNRTVIARVPKPRAIVLDPCQGYLYWADWDTHAKIERATLGGNFRVPIVNSSLVMP SGLTLDYEEDLLYWVDASLQRIERSTLTGVDREVIVNAAVHAFGLTLYGQYIYWTDLYTQRIYRANKYD GSGQIAMTTNLLSQPRGINTVVKNQKQQCNNPCEQFNGGCSHICAPGPNGAECQCPHEGNWYLANNRKH CIVDNGERCGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRC DYYNDCGDGSDEAGCLFRDCNATTEFMCNNRRCIPREFICNGVDNCHDNNTSDEKNCPDRTCQSGYTKC HNSNICIPRVYLCDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDEPAS CGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIP QSWVCDGDVDCTDGYDENQNCTRRTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGCLYQTCQQNQ FTCQNGRCISKTFVCDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSD EKGCGINECHDPSISGCDHNCTDTLTSFYCSCRPGYKLMSDKRTCVDIDECTEMPFVCSQKCENVIGSY ICKCAPGYLREPDGKTCRQNSNIEPYLIFSNRYYLRNLTIDGYFYSLILEGLDNVVALDFDRVEKRLYW IDTQRQVIERMFLNKTNKETIINHRLPAAESLAVDWVSRKLYWLDARLDGLFVSDLNGGHRRMLAQHCV DANNTFCFDNPRGLALHPQYGYLYWADWGHRAYIGRVGMDGTNKSVIISTKLEWPNGITIDYTNDLLYW ADAHLGYIEYSDLEGHHRHTVYDGALPHPFAITIFEDTIYWTDWNTRTVEKGNKYDGSNRQTLVNTTHR PFDIHVYHPYRQPIVSNPCGTNNGGCSHLCLIKPGGKGFTCECPDDFRTLQLSGSTYCMPMCSSTQFLC ANNEKCIPIWWKCDGQKDCSDGSDELALCPQRFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDEDRLL CENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVD NDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDEQGCEERTCHPVGDFR CKNHHCIPLRWQCDGQNDCGDNSDEENCAPRECTESEFRCVNQQCIPSRWICDHYNDCGDNSDERDCEM RTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGD DDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEY KCGNGHCIPHDNVCDDADDCGDWSDELGCNKGKERTCAENICEQNCTQLNEGGFICSCTAGFETNVFDR TSCLDINECEQFGTCPQHCRNTKGSYECVCADGFTSMSDRPGKRCAAEGSSPLLLLPDNVRIRKYNLSS ERFSEYLQDEEYIQAVDYDWDPEDIGLSVVYYTVRGEGSRFGAIKRAYIPNFESGRNNLVQEVDLKLKY VMQPDGIAVDWVGRHIYWSDVKNKRIEVAKLDGRYRKWLISTDLDQPAAIAVNPKLGLMFWTDWGKEPK LESAWMNGEDRNILVFEDLGWPTGLSIDYLNNDRIYWSDFKEDVIETIKYDGTDRRVIAKEAMNPYSLD IFEDQLYWISKEKGEVWKQNKFGQGKKEKTLVVNPWLTQVRIFHQLRYNKSVPNLCKQICSHLCLLRPG GYSCACPQGSSFIEGSTTECDAAIELPINLPPPCRCMHGGNCYFDETDLPKCKCPSGYTGKYCEMAFSK GISPGTTAVAVLLTILLIVVIGALAIAGFFHYRRTGSLLPALPKLPSLSSLVKPSENGNGVTFRSGADL NMDIGVSGFGPETAIDRSMAMSEDFVMEMGKQPIIFENPMYSARDSAVKVVQPIQVTVSENVDNKNYGS PINPSEIVPETNPTSPAADGTQVTKWNLFKRKSKQTTNFENPIYAQMENEQKESVAATPPPSPSLPAKP KPPSRRDPTPTYSATEDTFKDTANLVKEDSEV TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Restriction Sites	SgfI-MluI      Cloning Scheme for this gene      Plasmid Map
ACCN	NM_004525
ORF Size	13965 bp
OTI Disclaimer	Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation	This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Product Components	The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water).
Reconstitution	1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq Size	14392 bp
RefSeq ORF	13968 bp
Locus ID	4036
UniProt ID	P98164
Domains	ldl_recept_b, EGF_CA, ldl_recept_a, GBP_PSP, EGF, EGF
Protein Families	Druggable Genome, Transmembrane
Protein Pathways	Hedgehog signaling pathway
MW	521.9 kDa
Gene Summary	The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycoprotein has a large amino-terminal extracellular domain, a single transmembrane domain, and a short carboxy-terminal cytoplasmic tail. The extracellular ligand-binding-domains bind diverse macromolecules including albumin, apolipoproteins B and E, and lipoprotein lipase. The LRP2 protein is critical for the reuptake of numerous ligands, including lipoproteins, sterols, vitamin-binding proteins, and hormones. This protein also has a role in cell-signaling; extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of this membrane receptor is regulated by phosphorylation of its cytoplasmic domain. Mutations in this gene cause Donnai-Barrow syndrome (DBS) and facio-oculoacoustico-renal syndrome (FOAR).[provided by RefSeq, Aug 2009]

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