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MOV10 (NM_020963) Human Tagged ORF Clone
CAT＃: RC200934
MOV10 (Myc-DDK-tagged)-Human Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), transcript variant 1
ORF Plasmid: tGFP
"NM_020963" in other vectors (6)
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CNY 6,984.00
CNY 7,600.00
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | fSAP113; gb110 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>RC200934 ORF sequence
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCCAGTAAGTTCAGCTGCCGGCAGCTCCGGGAGGCGGGCCAGTGTTTCGAGAGTTTCCTGGTCGTTC GGGGACTGGACATGGAGACAGATCGCGAGCGGCTGCGGACCATTTATAACCGCGACTTCAAGATCAGCTT TGGGACCCCCGCCCCTGGCTTCTCCTCCATGCTGTATGGAATGAAGATTGCAAATCTGGCCTACGTCACC AAGACTCGGGTCAGGTTCTTCAGACTCGACCGCTGGGCCGACGTGCGGTTCCCAGAAAAGAGGAGAATGA AGCTGGGGTCAGATATCAGCAAACACCACAAGTCACTGCTAGCCAAGATCTTTTATGACAGGGCTGAGTA TCTTCATGGGAAACATGGTGTGGATGTGGAAGTCCAGGGGCCCCATGAAGCCCGAGATGGGCAGCTCCTT ATCCGCCTGGATTTGAACCGCAAAGAGGTGCTGACCCTGAGGCTTCGGAATGGCGGAACCCAGTCTGTTA CCCTCACTCACCTCTTCCCACTCTGCCGGACACCCCAGTTTGCTTTCTACAATGAAGACCAGGAGTTGCC CTGTCCACTGGGCCCCGGTGAATGCTATGAACTCCATGTCCATTGTAAGACCAGCTTTGTGGGCTACTTC CCAGCCACAGTGCTCTGGGAGCTGCTGGGACCTGGGGAGTCGGGTTCAGAAGGAGCCGGCACATTCTACA TTGCCCGCTTCTTGGCTGCCGTCGCCCACAGCCCCCTGGCTGCACAGCTGAAGCCCATGACTCCCTTCAA GCGGACCCGGATCACCGGAAACCCTGTGGTGACCAATCGGATAGAGGAAGGAGAGAGACCTGACCGCGCT AAGGGCTATGACCTGGAGTTAAGTATGGCGCTGGGGACATACTACCCACCTCCCCGCCTCAGGCAGCTGC TCCCCATGCTTCTTCAGGGAACAAGTATCTTCACTGCCCCTAAGGAGATCGCAGAGATCAAGGCCCAGCT GGAGACAGCCCTGAAGTGGAGGAACTATGAGGTGAAGCTGCGGCTGCTGCTGCACCTGGAGGAACTGCAG ATGGAGCATGATATCCGGCACTATGACCTGGAGTCGGTGCCCATGACCTGGGACCCTGTGGACCAGAACC CCAGGCTGCTCACGCTGGAGGTTCCTGGAGTGACTGAGAGCCGCCCCTCAGTGCTACGGGGCGACCACCT GTTTGCCCTTTTGTCCTCGGAGACACACCAGGAGGACCCCATCACATATAAGGGCTTTGTGCACAAGGTG GAATTGGACCGTGTCAAGCTGAGCTTTTCCATGAGCCTCCTGAGCCGCTTTGTGGATGGGCTGACCTTCA AGGTGAACTTTACCTTCAACCGCCAGCCGCTGCGAGTCCAGCACCGTGCCCTGGAGCTGACAGGGCGCTG GCTGCTGTGGCCCATGCTCTTTCCTGTGGCACCTCGGGACGTCCCGCTGCTGCCCTCAGATGTGAAACTC AAGCTGTACGACCGGAGTCTGGAGTCAAACCCAGAGCAGCTGCAGGCCATGAGGCACATTGTTACGGGCA CCACCCGTCCAGCCCCCTACATCATCTTTGGGCCTCCAGGCACCGGCAAGACTGTCACGTTAGTGGAGGC AATTAAGCAGGTGGTGAAGCACTTGCCCAAAGCCCACATCTTGGCCTGCGCTCCATCCAACTCAGGGGCT GACCTACTCTGTCAAAGGCTCCGGGTCCACCTTCCTAGCTCCATCTACCGCCTCCTGGCCCCCAGCAGGG ACATCCGCATGGTACCTGAGGACATCAAGCCCTGCTGCAACTGGGACGCAAAGAAGGGGGAGTATGTATT TCCCGCCAAGAAGAAGCTGCAGGAATACCGGGTCTTAATTACCACCCTCATCACTGCCGGCAGGTTGGTC TCGGCCCAGTTTCCCATTGATCACTTCACACACATCTTCATCGATGAGGCTGGCCACTGCATGGAGCCTG AGAGTCTGGTAGCTATAGCAGGGCTGATGGAAGTAAAGGAAACAGGTGATCCAGGAGGGCAGCTGGTGCT GGCAGGAGACCCTCGGCAGCTGGGGCCTGTGCTGCGTTCCCCACTGACCCAGAAGCATGGACTGGGATAC TCACTGCTGGAGCGGCTGCTCACCTACAACTCCCTGTACAAGAAGGGCCCTGATGGCTATGACCCCCAGT TCATAACCAAGCTGCTCCGCAACTACAGGTCTCATCCCACCATCCTGGACATTCCTAACCAGCTCTATTA TGAAGGGGAGCTGCAGGCCTGTGCTGATGTCGTGGATCGAGAACGCTTCTGCCGCTGGGCGGGCCTACCT CGACAGGGCTTTCCCATCATCTTTCACGGCGTAATGGGCAAAGATGAGCGTGAAGGCAACAGCCCATCCT TCTTCAACCCTGAAGAGGCTGCCACAGTGACTTCCTACCTGAAGCTGCTCCTGGCCCCCTCCTCCAAGAA GGGCAAAGCTCGCCTGAGCCCTCGAAGTGTGGGCGTCATCTCCCCGTACCGGAAACAGGTGGAGAAAATC CGTTACTGCATCACCAAACTTGACAGGGAGCTTCGAGGACTGGATGACATCAAGGACTTGAAGGTGGGTT CAGTAGAAGAATTCCAAGGCCAAGAACGAAGCGTCATCCTCATCTCCACCGTGCGAAGCAGCCAGAGCTT TGTGCAGCTGGATCTGGACTTTAATCTGGGTTTCCTTAAGAACCCCAAGAGGTTCAATGTAGCTGTGACC CGGGCCAAGGCCCTGCTCATCATCGTGGGGAACCCCCTTCTCCTGGGCCATGACCCTGACTGGAAAGTAT TCCTGGAGTTCTGTAAAGAAAACGGAGGGTATACCGGGTGTCCCTTCCCTGCCAAACTGGACCTGCAACA GGGACAGAATTTACTGCAAGGTCTGAGCAAGCTCAGCCCCTCTACCTCAGGGCCCCACAGCCATGACTAC CTCCCCCAGGAGCGGGAGGGTGAAGGGGGCCTGTCTCTGCAAGTGGAGCCAGAGTGGAGGAATGAGCTC ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >RC200934 protein sequence
Red=Cloning site Green=Tags(s) MPSKFSCRQLREAGQCFESFLVVRGLDMETDRERLRTIYNRDFKISFGTPAPGFSSMLYGMKIANLAYVT KTRVRFFRLDRWADVRFPEKRRMKLGSDISKHHKSLLAKIFYDRAEYLHGKHGVDVEVQGPHEARDGQLL IRLDLNRKEVLTLRLRNGGTQSVTLTHLFPLCRTPQFAFYNEDQELPCPLGPGECYELHVHCKTSFVGYF PATVLWELLGPGESGSEGAGTFYIARFLAAVAHSPLAAQLKPMTPFKRTRITGNPVVTNRIEEGERPDRA KGYDLELSMALGTYYPPPRLRQLLPMLLQGTSIFTAPKEIAEIKAQLETALKWRNYEVKLRLLLHLEELQ MEHDIRHYDLESVPMTWDPVDQNPRLLTLEVPGVTESRPSVLRGDHLFALLSSETHQEDPITYKGFVHKV ELDRVKLSFSMSLLSRFVDGLTFKVNFTFNRQPLRVQHRALELTGRWLLWPMLFPVAPRDVPLLPSDVKL KLYDRSLESNPEQLQAMRHIVTGTTRPAPYIIFGPPGTGKTVTLVEAIKQVVKHLPKAHILACAPSNSGA DLLCQRLRVHLPSSIYRLLAPSRDIRMVPEDIKPCCNWDAKKGEYVFPAKKKLQEYRVLITTLITAGRLV SAQFPIDHFTHIFIDEAGHCMEPESLVAIAGLMEVKETGDPGGQLVLAGDPRQLGPVLRSPLTQKHGLGY SLLERLLTYNSLYKKGPDGYDPQFITKLLRNYRSHPTILDIPNQLYYEGELQACADVVDRERFCRWAGLP RQGFPIIFHGVMGKDEREGNSPSFFNPEEAATVTSYLKLLLAPSSKKGKARLSPRSVGVISPYRKQVEKI RYCITKLDRELRGLDDIKDLKVGSVEEFQGQERSVILISTVRSSQSFVQLDLDFNLGFLKNPKRFNVAVT RAKALLIIVGNPLLLGHDPDWKVFLEFCKENGGYTGCPFPAKLDLQQGQNLLQGLSKLSPSTSGPHSHDY LPQEREGEGGLSLQVEPEWRNEL TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_020963 |
| ORF Size | 3009 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_020963.4 |
| RefSeq Size | 3767 bp |
| RefSeq ORF | 3012 bp |
| Locus ID | 4343 |
| UniProt ID | Q9HCE1 |
| MW | 113.7 kDa |
| Gene Summary | 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs (PubMed:24726324). Required for microRNA (miRNA)-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC (PubMed:16289642, PubMed:17507929, PubMed:22791714). In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2 (PubMed:25464849). Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1 (PubMed:30122351, PubMed:23093941). Facilitates LINE-1 uridylation by TUT4 and TUT7 (PubMed:30122351). Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development: suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity). May function as a messenger ribonucleoprotein (mRNP) clearance factor (PubMed:24726324).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200934L1 | Lenti ORF clone of Human Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), transcript variant 1, Myc-DDK-tagged |
CNY 9,384.00 |
|
| RC200934L2 | Lenti ORF clone of Human Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), transcript variant 1, mGFP tagged |
CNY 10,450.00 |
|
| RC200934L3 | Lenti ORF clone of Human Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), transcript variant 1, Myc-DDK-tagged |
CNY 9,384.00 |
|
| RC200934L4 | Lenti ORF clone of Human Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), transcript variant 1, mGFP tagged |
CNY 9,384.00 |
|
| RG200934 | MOV10 (tGFP-tagged) - Human Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), transcript variant 1 |
CNY 8,584.00 |
|
| SC320191 | MOV10 (untagged)-Human Mov10, Moloney leukemia virus 10, homolog (mouse) (MOV10), transcript variant 1 |
CNY 6,992.00 |
