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Frs2 (NM_177798) Mouse Tagged ORF Clone
CAT＃: MR208163
- TrueORF®
Frs2 (Myc-DDK-tagged) - Mouse fibroblast growth factor receptor substrate 2 (Frs2)
ORF Plasmid: tGFP
"NM_177798" in other vectors (4)
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CNY 3,784.00
CNY 4,560.00
| Cited in 1 publication. |
Product images
CNY 300.00
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | Myc-DDK |
| Synonyms | 4732458E18; C330018A15Rik; Frs2alpha; SNT1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MR208163 representing NM_177798
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGTAGCTGTTGTAGCTGTCCAGATAAAGACACTGTCCCAGATAACCATCGGAACAAGTTTAAGGTCA TTAATGTGGATGATGATGGGAATGAGCTAGGCTCTGGTGTGATGGAACTCACAGACACAGAGCTGATTCT GTACACCCGGAAACGGGACTCGGTAAAATGGCACTACCTCTGCCTACGACGATACGGCTATGACTCAAAT CTGTTTTCTTTTGAAAGTGGTCGAAGGTGTCAGACTGGACAAGGAATTTTTGCTTTTAAGTGTGCCCGTG CAGAAGAATTATTTAACATGTTGCAAGAGATTATGCAAAATAATAGTATAAATGTGGTGGAAGAGCCGGT TGTAGAAAGGAGTAGTCATCAGACAGAGCTGGAAGTCCCTAGGACACCTCGGACACCTACAACTCCAGGG CTCGGTGCTCAGAACTTACCTAATGGGTATCCCCGCTACCCCTCGTTTGGAGACGCTTCATCCCACCCCT CAAGCCGGCATCCTTCGGTGGGAAGTGCTCGCTTACCTTCAGTCGGTGAAGAGTCCACACACCCTTTGCT CGTGGCTGAGGAACAAGTACATACTTATGTTAACACTACAGGTGTGCAAGAGGAGCGAAAAAACCGTGCA AGTGTGCATGTTCCCCCAGAGGCAAGGGTTTCTAATGCTGAGAGCAACACACCAAAAGAAGAGCCGAGTA ACCCCGAGGACAGGGACCCGCAAGTGCTTCTTAAGCCTGAAGGAGTCAGGTTTGTGCTAGGACCAACCCC TGTCCAGAAGCAGTTAATGGAAAAGGAGAAACTGGAGCAACTGGGAAAAGACCCAGTCAGTGGGAGTGGA GCGGGCAACACGGAGTGGGACACCGGCTATGACAGTGACGAGCGCAGAGATGTGCCCCCTGTCAACAAAC TGGTGTATGAAAATATAAACGGGCTATCTATTCCCAGTGCCTCAGGGGTCAGGAGAGGTCGTCTGACATC TACCAGCACCTCAGACACCCAGAATATCAACAACTCAGCGCAGAGAAGACCTGCACTATTAAACTATGAA AATTTACCATCTTTGCCTCCTGTTTGGGAAGCCCGCAAGCTCAGTAGGGATGAAGATGACAATTTAGGAC CAAAGACCCCATCTCTAAATGGCTACCATAATAATCTAGATCCAATGCATAACTATGTTAATACAGAGAA TGTAACAGTGCCGGCAAGTGCTCACAAAATAGACTATTCGAAGCGCAGGGATTGTACACCGACAGTCTTT AACTTTGATATCAGGCGACCCAGTTTAGAACATAGGCAACTCAATTATATACAGGTGGATTTGGAAGGGG GCAGTGACTCTGACAACCCTCAGACTCCAAAAACGCCGACCACTCCCCTCCCGCAAACCCCCACGCGGCG CACAGAGCTGTACGCTGTGATAGACATTGAGAGAACTGCTGCTATGTCCAACTTGCAGAAAGCGCTGCCT CGAGACGACGGTACATCTCGGAAGACGAGGCACAATAGTACTGACCTGCCCATG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA >MR208163 representing NM_177798
Red=Cloning site Green=Tags(s) MGSCCSCPDKDTVPDNHRNKFKVINVDDDGNELGSGVMELTDTELILYTRKRDSVKWHYLCLRRYGYDSN LFSFESGRRCQTGQGIFAFKCARAEELFNMLQEIMQNNSINVVEEPVVERSSHQTELEVPRTPRTPTTPG LGAQNLPNGYPRYPSFGDASSHPSSRHPSVGSARLPSVGEESTHPLLVAEEQVHTYVNTTGVQEERKNRA SVHVPPEARVSNAESNTPKEEPSNPEDRDPQVLLKPEGVRFVLGPTPVQKQLMEKEKLEQLGKDPVSGSG AGNTEWDTGYDSDERRDVPPVNKLVYENINGLSIPSASGVRRGRLTSTSTSDTQNINNSAQRRPALLNYE NLPSLPPVWEARKLSRDEDDNLGPKTPSLNGYHNNLDPMHNYVNTENVTVPASAHKIDYSKRRDCTPTVF NFDIRRPSLEHRQLNYIQVDLEGGSDSDNPQTPKTPTTPLPQTPTRRTELYAVIDIERTAAMSNLQKALP RDDGTSRKTRHNSTDLPM TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
| Chromatograms |
CHROMATOGRAMS
 Sequencher program is needed, download here. |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_177798 |
| ORF Size | 1524 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_177798.3, NP_808466.1 |
| RefSeq Size | 5701 bp |
| RefSeq ORF | 1527 bp |
| Locus ID | 327826 |
| UniProt ID | Q8C180 |
| MW | 57.2 kDa |
| Gene Summary | Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.[UniProtKB/Swiss-Prot Function] |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
LRTM1 promotes the differentiation of myoblast cells by negatively regulating the FGFR1 signaling pathway
,Li, HK;Zhou, Y;Ding, J;Xiong, L;Shi, YX;He, YJ;Yang, D;Deng, ZL;Nie, M;Fei Gao, Y;,
Exp. Cell Res.
,PubMed ID 32841643
[FRS2]
|
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC217223 | Frs2 (untagged) - Mouse fibroblast growth factor receptor substrate 2 (Frs2), (10ug) |
CNY 6,560.00 |
|
| MG208163 | Frs2 (tGFP-tagged) - Mouse fibroblast growth factor receptor substrate 2 (Frs2) |
CNY 5,040.00 |
|
| MR208163L3 | Lenti ORF clone of Frs2 (Myc-DDK-tagged) - Mouse fibroblast growth factor receptor substrate 2 (Frs2) |
CNY 6,460.00 |
|
| MR208163L4 | Lenti ORF clone of Frs2 (mGFP-tagged) - Mouse fibroblast growth factor receptor substrate 2 (Frs2) |
CNY 6,460.00 |
