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Sorl1 (NM_011436) Mouse Tagged ORF Clone
CAT＃: MG223474
- TrueORF®
Sorl1 (tGFP-tagged) - Mouse sortilin-related receptor LDLR class A repeats-containing (Sorl1), (10ug)
ORF Plasmid: DDK
"NM_011436" in other vectors (2)
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CNY 26,700.00
货期*
9周
规格
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经常一起买 (4)
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | 2900010L19Rik; AI596264; AW261561; gp250; LR11; mSorLA; SorLA |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG223474 representing NM_011436
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGACACGGAGCAGCAGGAGGGAGTCGAGACTCCCTTTCCTATTCGCCCTGGTCGCGCTGCTACCCC GCGGGGCTCTCGGCGGGGGCTGGACGCAGAGATTGCACGGTGGCCCGGCGCCCTTGCCCCAGGACCGGGG CTTCTTCGTGGTGCAGGGCGACCCGCGCGATCTCCGGCTAGGAACGCACGGGGATGCCCCGGGGGCGAGC CCGGCGGCCAGGAAGCCACTCAGGACCCGGCGGAGCGCTGCTCTGCAGCCCCAGCCTATCCAGGTGTATG GACAGGTCAGTCTGAATGACTCCCACAATCAGATGGTGGTGCACTGGGCCGGAGAGAAAAGCAACGTGAT CGTGGCATTAGCCCGAGACAGCCTGGCGTTGGCAAGGCCCAAGAGCAGTGATGTGTATGTGTCTTACGAC TATGGAAAATCATTCAGTAAGATTTCAGAGAAGCTGAACTTTGGCGTGGGCAACAACAGCGAAGCTGTGA TCTCCCAGTTCTACCACAGCCCTGCTGACAACAAGAGGTACATCTTTGTGGATGCTTACGCCCAATACCT CTGGATCACATTTGACTTCTGCAGCACTATCCATGGCTTCTCCATCCCATTCCGGGCGGCTGATCTCCTC CTCCATAGCAAGGCCTCCAACCTCCTCTTGGGCTTTGACAGGTCTCACCCCAACAAGCAGCTATGGAAGT CAGATGATTTTGGCCAGACCTGGATCATGATTCAGGAACACGTGAAGTCCTTCTCTTGGGGAATCGACCC CTATGATCAGCCAAACGCTATCTACATTGAGCGACATGAACCCTTTGGGTTCTCCACAGTGCTCCGCAGT ACAGACTTCTTCCAGTCCCGGGAAAACCAGGAAGTGATCCTGGAGGAAGTGAGAGACTTTCAGCTTCGCG ACAAGTATATGTTTGCTACAAAGGTGGTGCATCTTCCGGGCAGCCAGCAGCAGTCATCTGTCCAGCTCTG GGTCTCCTTTGGCCGGAAGCCTATGAGAGCAGCCCAGTTTGTCACAAAGCATCCTATTAATGAATATTAC ATCGCTGATGCCGCCGAGGACCAGGTGTTCGTGTGTGTTAGCCACAGTAACAACAGCACTAACTTATACA TCTCAGAGGCAGAGGGGCTGAAGTTCTCCCTCTCCTTGGAGAATGTGCTGTATTACAGCCCAGGAGGGGC CGGCAGTGACACTCTGGTGAGGTATTTTGCAAATGAGCCGTTTGCCGACTTTCACCGCGTGGAAGGCTTA CAAGGAGTCTATATTGCCACCCTGATTAATGGTTCTATGAATGAGGAGAACATGAGGTCGGTCATCACCT TTGACAAAGGGGGAACCTGGGAATTTCTTCAGGCCCCAGCCTTCACAGGATATGGAGAGAAAATCAATTG TGAGCTTTCTCAGGGTTGTTCCCTCCACCTGGCCCAGCGCCTCAGTCAACTGCTCAACCTCCAACTTCGG AGGATGCCTATCCTATCCAAGGAGTCAGCCCCCGGTCTCATCATTGCTACCGGCTCTGTGGGAAAGAACT TGGCCAGCAAGACCAATGTGTACATCTCTAGCAGTGCTGGAGCCAGGTGGAGAGAGGCTCTTCCCGGACC TCATTACTATACTTGGGGTGACCATGGAGGCATCATCATGGCGATTGCCCAGGGCATGGAGACCAACGAG CTGAAGTACAGCACCAATGAAGGGGAGACCTGGAAGACGTTCGTCTTCTCGGAGAAGCCTGTGTTTGTGT ATGGGCTTCTCACAGAACCTGGTGAGAAGAGCACCGTCTTCACCATCTTCGGCTCGAACAAGGAGAGTGT CCACAGCTGGCTCATCCTGCAGGTCAATGCCACTGATGCCTTGGGGGTTCCTTGCACAGAAAACGACTAC AAGCTGTGGTCCCCATCTGATGAGCGAGGAAATGAGTGTTTGCTAGGACACAAGACAGTTTTCAAAAGGA GGACCCCTCATGCCACGTGCTTTAATGGGGAAGACTTTGACCGGCCAGTGGTTGTGTCCAACTGCTCCTG CACCCGGGAGGACTACGAATGTGACTTTGGCTTCAAGATGAGCGAAGATCTCTCCTTAGAGGTTTGTGTT CCAGACCCTGAGTTTTCTGGGAAGCCCTACAGCCCTCCTGTGCCTTGTCCTGTGGGTTCTTCATACAGGA GAACGAGAGGCTATCGGAAGATTTCTGGGGATACGTGCAGTGGAGGAGACGTTGAAGCGCGGCTGGAAGG GGAGCTGGTCCCCTGTCCCCTTGCAGAAGAGAATGAGTTCATCCTATACGCCATGCGCAAGTCCATCTAC CGCTACGACTTGGCCTCGGGAGCCACAGAGCAGCTTCCTCTCTCGGGGCTGCGGGCGGCTGTGGCCCTGG ACTTTGACTATGAACGCAACTGCTTGTATTGGTCTGACCTGGCGCTGGACACCATCCAGCGTCTCTGCTT GAACGGGAGCACAGGGCAGGAGGTGATCATCAATTCCGGCCTGGAGACCGTGGAGGCTTTGGCCTTCGAA CCCCTCAGCCAATTACTTTACTGGGTGGATGCCGGCTTTAAAAAGATCGAGGTAGCTAATCCAGATGGTG ACTTCCGACTGACAATCGTCAATTCCTCTGTGCTTGATCGACCCAGGGCTTTAGTCCTTGTACCCCAAGA AGGGGTGATGTTCTGGACTGACTGGGGGGACCTGAAGCCTGGGATTTACCGGAGCTACATGGACGGCTCT GCTGCCTACCGCCTTGTGTCAGAGGACGTGAAGTGGCCCAATGGCATCTCTGTGGACAGCCAGTGGATCT ACTGGACGGATGCTTACCTGGACTGTATCGAGCGCATCACTTTCAGTGGCCAGCAGCGTTCAGTCATCCT TGACAGCCTCCCACACCCCTATGCCATCGCTGTCTTTAAGAATGAGATCTACTGGGATGACTGGTCACAG CTCAGCATCTTCAGAGCTTCGAAGCACAGCAGATCCCAGGTGGAGATTCTAGCAAGCCAGCTCACGGGCC TCATGGACATGAAGGTTTTCTACAAGGGAAAGAATGCTGGAAGCAACGCTTGTGTCCCTCAGCCCTGCAG TCTACTGTGCCTCCCTAAGGCCAACAACAGCAAAAGCTGCAGGTGTCCAGAAGGTGTGGCCAGCAGTGTC CTCCCCTCTGGGGACCTGATGTGTGACTGCCCTCAGGGCTATCAAAGGAAGAACAACACCTGTGTCAAAG AAGAGAACACCTGTCTCCGAAACCAGTATCGCTGCAGCAACGGCAACTGTATCAACAGCATTTGGTGGTG TGATTTCGACAATGACTGTGGAGACATGAGTGACGAGAGAAATTGCCCCACGACGGTCTGTGATGCAGAC ACTCAGTTCCGGTGCCAGGAGTCGGGGACTTGCATTCCACTCTCCTATAAGTGTGACCTTGAAGATGACT GTGGAGATAACAGTGATGAGAGTCACTGTGAGATGCACCAGTGTCGTAGCGACGAGTTCAACTGCAGCTC TGGGATGTGCATCCGGTCCTCCTGGGTGTGCGATGGAGACAACGACTGTAGGGACTGGTCTGATGAAGCC AACTGTACTGCCATCTATCATACCTGTGAGGCCTCCAACTTCCAGTGCCACAATGGCCACTGCATCCCCC AGCGATGGGCATGTGACGGTGATGCGGATTGCCAGGATGGCTCTGACGAAGATCCCGTCAGCTGTGAGAA AAAGTGCAATGGATTCCACTGCCCAAACGGCACGTGCATCCCGTCCAGCAAGCATTGTGATGGGCTGAGG GACTGCCCCGACGGCTCCGATGAGCAGCACTGTGAGCCCTTCTGCACGCGCTTCATGGACTTCGTGTGTA AGAACCGTCAGCAGTGTCTGTTCCACTCCATGGTGTGTGACGGGATCGTCCAGTGCCGAGATGGCTCTGA TGAGGATGCGGCCTTCGCTGGATGCTCGCAAGACCCCGAGTTCCACAAGGAGTGCGATGAGTTCGGCTTC CAGTGTCAGAACGGAGTGTGCATCAGCTTGATTTGGAAATGCGATGGGATGGATGACTGCGGGGACTACT CTGACGAGGCCAACTGTGAAAACCCCACGGAAGCCCCAAACTGTTCCCGTTACTTTCAGTTCCACTGTGA GAATGGCCACTGCATCCCCAACAGGTGGAAATGTGACAGAGAGAACGACTGTGGGGACTGGTCTGATGAG AAGGATTGTGGAGATTCACATGTTCTACCCTCCCCGACCCCCGGGCCCTCCACGTGTCTGCCCAATTACT TCCACTGCAGCAGCGGGGCCTGTGTGATGGGCACCTGGGTGTGCGACGGCTACAGGGACTGTGCAGATGG CTCTGATGAGGAGGCCTGCCCCTCTCTAGCAAACTCCACTGCCGCCTCCACTCCCACCCAGTTCGGGCAG TGCGACCGATTTGAGTTCGAGTGTCACCAACCAAAGAAATGTATCCCCAACTGGAAGCGCTGTGACGGCC ACCAAGATTGCCAAGACGGCCAGGATGAAGCCAACTGCCCCACTCACAGCACCTTGACCTGTACGAGCAG GGAGTTCAAGTGTGAGGACGGCGAGGCATGCATCGTGCTCTCGGAGCGCTGTGATGGCTTCCTGGATTGC TCTGATGAGAGCGATGAGAAGGCCTGCAGCGATGAGTTAACTGTATACAAAGTGCAGAATCTCCAGTGGA CAGCTGATTTCTCCGGAGATGTGACTTTGACCTGGATGCGGCCAAAGAAAATGCCATCTGCTTCTTGTGT ATACAATGTCTACTACAGGGTGGTTGGAGAGAGCATATGGAAGACCCTGGAAACCCACAGCAATAAAACA AGCACTGTGCTCAAGGTCCTGAAGCCAGACACCACGTACCAGGTTAAGGTCCAGGTGCACTGCCTCAACA AGGTGCACAACACCAATGACTTTGTGACCCTCAGGACTCCAGAAGGGTTGCCAGATGCCCCTCGGAATCT CCAGCTCTCCCTGAACAGTGAAGAGGAAGGTGTGATTCTCGGGCACTGGGCTCCTCCCGTCCACACCCAT GGCCTCATCCGTGAGTACATTGTGGAATACAGCAGGAGTGGGTCCAAGATGTGGGCCTCCCAGAGAGCTG CTAGCAACTCTACAGAAATAAAGAACTTACTGCTCAATGCCCTCTACACTGTCAGAGTGGCTGCGGTGAC TAGTCGTGGGATAGGAAACTGGAGCGATTCTAAGTCCATCACCACCATAAAAGGAAAAGTGATCCAAGCA CCAAATATCCACATTGACAGCTACGATGAAAATTCTCTGAGCTTTACCCTGACCATGGATGGTGACATCA AGGTCAATGGCTACGTGGTGAACCTTTTCTGGTCATTTGATGCCCACAAACAAGAAAAGAAAACCCTGAG CTTCCGCGGAGGGAGTGCACTGTCACACAGAGTTAGCAACCTGACAGCTCATACATCCTATGAGATTTCT GCCTGGGCCAAGACAGACTTGGGAGATAGCCCACTGGCCTTTGAGCACATCTTGACCAGAGGCAGCAGTC CACCAGCTCCTAGTCTCAAAGCCAAGGCCATCAATCAGACTGCAGTGGAGTGCATCTGGACTGGCCCCAA GAATGTGGTGTATGGTATTTTCTATGCCACATCCTTCCTTGACCTCTACCGAAACCCTAAGAGCGTAACT ACTTCGCTCCACAATAAGACAGTCATCGTCAGCAAGGATGAGCAGTATCTGTTTCTGGTCCGGGTGTTGA TCCCTTACCAAGGGCCGTCTTCTGACTACGTTGTAGTGAAGATGATCCCAGACAGCAGGCTCCCGCCTCG GCATCTGCACGCGGTCCACATAGGCAAAACCTCAGCACTCATCAAATGGGAATCGCCCTATGACTCTCCT GACCAGGACTTGTTCTACGCCATTGCAGTGAAAGATCTGATCAGGAAGACGGACAGAAGCTACAAAGTCA GATCCCGCAACAGTACTGTGGAGTACAGCCTAAGCAAGCTGGAACCTGGAGGGAAATACCACATCATTGT CCAGCTGGGAAACATGAGCAAGGATTCCAGCATAAAAATCACCACAGTTTCGTTATCAGCACCTGATGCC TTAAAAATCATAACGGAAAACGACCACGTTCTCCTCTTTTGGAAAAGCCTAGCACTGAAGGAAAAGCAGT TCAATGAAACCAGGGGCTATGAGATCCACATGTCTGACAGCGCTGTGAATCTCACCGCTTACCTCGGGAA TACTACGGACAATTTCTTTAAAGTGTCCAACCTGAAGATGGGTCATAACTACACTTTCACGGTCCAAGCG CGGTGTCTCTTTGGTAGCCAGATCTGTGGGGAGCCCGCCGTGCTGCTGTACGATGAACTGAGCTCAGGTG CAGATGCGGCAGTGATCCAGGCTGCCCGGTCTACTGATGTTGCAGCTGTGGTGGTTCCCATCCTGTTCCT GATCCTGCTGAGCCTGGGTGTCGGCTTCGCCATCCTCTACACGAAGCACCGTCGCTTACAAAGCAGCTTC AGCGCTTTCGCCAACAGCCACTACAGCTCCAGGCTGGGCTCGGCCATCTTCTCCTCAGGGGATGACCTAG GAGAGGACGATGAAGATGCTCCCATGATTACTGGATTCTCAGACGATGTCCCCATGGTGATAGCG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG223474 representing NM_011436
Red=Cloning site Green=Tags(s) MATRSSRRESRLPFLFALVALLPRGALGGGWTQRLHGGPAPLPQDRGFFVVQGDPRDLRLGTHGDAPGAS PAARKPLRTRRSAALQPQPIQVYGQVSLNDSHNQMVVHWAGEKSNVIVALARDSLALARPKSSDVYVSYD YGKSFSKISEKLNFGVGNNSEAVISQFYHSPADNKRYIFVDAYAQYLWITFDFCSTIHGFSIPFRAADLL LHSKASNLLLGFDRSHPNKQLWKSDDFGQTWIMIQEHVKSFSWGIDPYDQPNAIYIERHEPFGFSTVLRS TDFFQSRENQEVILEEVRDFQLRDKYMFATKVVHLPGSQQQSSVQLWVSFGRKPMRAAQFVTKHPINEYY IADAAEDQVFVCVSHSNNSTNLYISEAEGLKFSLSLENVLYYSPGGAGSDTLVRYFANEPFADFHRVEGL QGVYIATLINGSMNEENMRSVITFDKGGTWEFLQAPAFTGYGEKINCELSQGCSLHLAQRLSQLLNLQLR RMPILSKESAPGLIIATGSVGKNLASKTNVYISSSAGARWREALPGPHYYTWGDHGGIIMAIAQGMETNE LKYSTNEGETWKTFVFSEKPVFVYGLLTEPGEKSTVFTIFGSNKESVHSWLILQVNATDALGVPCTENDY KLWSPSDERGNECLLGHKTVFKRRTPHATCFNGEDFDRPVVVSNCSCTREDYECDFGFKMSEDLSLEVCV PDPEFSGKPYSPPVPCPVGSSYRRTRGYRKISGDTCSGGDVEARLEGELVPCPLAEENEFILYAMRKSIY RYDLASGATEQLPLSGLRAAVALDFDYERNCLYWSDLALDTIQRLCLNGSTGQEVIINSGLETVEALAFE PLSQLLYWVDAGFKKIEVANPDGDFRLTIVNSSVLDRPRALVLVPQEGVMFWTDWGDLKPGIYRSYMDGS AAYRLVSEDVKWPNGISVDSQWIYWTDAYLDCIERITFSGQQRSVILDSLPHPYAIAVFKNEIYWDDWSQ LSIFRASKHSRSQVEILASQLTGLMDMKVFYKGKNAGSNACVPQPCSLLCLPKANNSKSCRCPEGVASSV LPSGDLMCDCPQGYQRKNNTCVKEENTCLRNQYRCSNGNCINSIWWCDFDNDCGDMSDERNCPTTVCDAD TQFRCQESGTCIPLSYKCDLEDDCGDNSDESHCEMHQCRSDEFNCSSGMCIRSSWVCDGDNDCRDWSDEA NCTAIYHTCEASNFQCHNGHCIPQRWACDGDADCQDGSDEDPVSCEKKCNGFHCPNGTCIPSSKHCDGLR DCPDGSDEQHCEPFCTRFMDFVCKNRQQCLFHSMVCDGIVQCRDGSDEDAAFAGCSQDPEFHKECDEFGF QCQNGVCISLIWKCDGMDDCGDYSDEANCENPTEAPNCSRYFQFHCENGHCIPNRWKCDRENDCGDWSDE KDCGDSHVLPSPTPGPSTCLPNYFHCSSGACVMGTWVCDGYRDCADGSDEEACPSLANSTAASTPTQFGQ CDRFEFECHQPKKCIPNWKRCDGHQDCQDGQDEANCPTHSTLTCTSREFKCEDGEACIVLSERCDGFLDC SDESDEKACSDELTVYKVQNLQWTADFSGDVTLTWMRPKKMPSASCVYNVYYRVVGESIWKTLETHSNKT STVLKVLKPDTTYQVKVQVHCLNKVHNTNDFVTLRTPEGLPDAPRNLQLSLNSEEEGVILGHWAPPVHTH GLIREYIVEYSRSGSKMWASQRAASNSTEIKNLLLNALYTVRVAAVTSRGIGNWSDSKSITTIKGKVIQA PNIHIDSYDENSLSFTLTMDGDIKVNGYVVNLFWSFDAHKQEKKTLSFRGGSALSHRVSNLTAHTSYEIS AWAKTDLGDSPLAFEHILTRGSSPPAPSLKAKAINQTAVECIWTGPKNVVYGIFYATSFLDLYRNPKSVT TSLHNKTVIVSKDEQYLFLVRVLIPYQGPSSDYVVVKMIPDSRLPPRHLHAVHIGKTSALIKWESPYDSP DQDLFYAIAVKDLIRKTDRSYKVRSRNSTVEYSLSKLEPGGKYHIIVQLGNMSKDSSIKITTVSLSAPDA LKIITENDHVLLFWKSLALKEKQFNETRGYEIHMSDSAVNLTAYLGNTTDNFFKVSNLKMGHNYTFTVQA RCLFGSQICGEPAVLLYDELSSGADAAVIQAARSTDVAAVVVPILFLILLSLGVGFAILYTKHRRLQSSF SAFANSHYSSRLGSAIFSSGDDLGEDDEDAPMITGFSDDVPMVIA TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_011436 |
| ORF Size | 6645 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_011436.4 |
| RefSeq Size | 6938 bp |
| RefSeq ORF | 6648 bp |
| Locus ID | 20660 |
| UniProt ID | O88307 |
| Gene Summary | Likely to be a multifunctional endocytic receptor, that may be implicated in the uptake of lipoproteins and of proteases. Binds LDL, the major cholesterol-carrying lipoprotein of plasma, and transports it into cells by endocytosis. Binds the receptor-associated protein (RAP). Could play a role in cell-cell interaction. May play a role in neural organization, as well as the establishment of embryonic organ systems. Involved in APP trafficking to and from the Golgi apparatus (By similarity). It probably acts as a sorting receptor that protects APP from trafficking to late endosome and from processing into amyloid beta (By similarity). Involved in the regulation of smooth muscle cells migration, probably through PLAUR binding and decreased internalization.[UniProtKB/Swiss-Prot Function] |
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