Slc5a8 (BC017691) Mouse Tagged ORF Clone
CAT＃: MG208933
- TrueORF®
Slc5a8 (tGFP-tagged) - Mouse solute carrier family 5 (iodide transporter), member 8 (cDNA clone MGC:19357 IMAGE:4239161)
ORF Plasmid: DDK
"BC017691" in other vectors (4)
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CNY 3520.00
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Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | MGC19357, Ait |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG208933 representing BC017691
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGGCGGTCGCAGTATGTCCGCCGTGCCTGTGGCTCTGTCCCTCACCGCCAGCTTCATGTCCGCTGTCA CTGTCCTGGGCACTCCTGCCGAGGTCTACCGTTTTGGGGCGATATTCAGCATCTTTGTCATCACCTACTT TTTTGTAGTGGTTATCAGCGCGGAGGTCTTCCTTCCAGTGTTCTATAGGCTGGGGATCACCAGCACCTAC GAGTATTTGGAACTTCGATTTAATCGATGCATTCGTCTCTGTGGCACAATCCTCTTCATCGTTCAAACAA TTCTGTACACTGGAATTGTGATTTATGCCCCTGCTCTGGCTTTGAATCAAGTTACAGGATTTGATCTGTG GGGCGCAGTGGTGGCCACAGGGGTGGTCTGCACATTCTACTGCACACTGGGCGGTCTTAAAGCAGTTGTC TGGACAGATGTTTTTCAAGTTGGGATCATGGTGGCTGGATTTGCATCCGTAATTATACAGGCATCAATAA CTCAACATGGCATCAATAAGATTTTAAGTGATGCTTTTAATGGTGGAAGATTAAACTTCTGGAATTTTGA TCCTAACCCTTTGCAAAGACACACGTTCTGGACAATTGTCATTGGAGGGACTTTTACCTGGACCACCATC TATGGTGTCAACCAGTCCCAAGTGCAGAGATATATTTCCTGTAAAAGCAGACTCCATGCAAAACTGTCCC TCTATGTCAACCTTGTGGGCCTCTGGGTGATCCTCACCTGCTCCATATTCTGTGGGCTTGCCCTGTACTC CAGATACCGTGAATGTGATCCCTGGACATCTAAGAAAGTGTCAGCGATTGACCAGCTTATGCCTTATTTG GTGTTGGACATTTTGAAAAATTACCCTGGTGTTCCCGGACTTTTTGTGGCCTGCGCTTACAGTGGGACAT TAAGCACAGTGTCCTCCAGTATCAATGCCTTGGCGGCAGTCACCGTGGAAGATCTCATCAAACCCCGCTT CAAGTCTCTCTCAGAGAAGTCTCTGTCTTGGATTTCCCAAGGAATGAGTGTCCTGTATGGAGCTCTGTGC ATTGGAATGGCTGCCCTGGCATCGCTGATGGGAGCCTTGTTACAGGCAGCACTCAGCATATTCGGCATGG TTGGTGGACCACTTCTGGGCTTGTTTTCTTTGGGCATCTTGGTCCCCTTCGCCAACTCAATTGGAGCACT CACTGGTCTGTTGGCTGGATTTGCCATTTCCTTATGGGTAGGAATTGGAGCCCAGCTTTACCCTCCGCTT CCTGAGAGAACCTTACCATTGCCCCTTGAAACCTATGGCTGTAACATCACGCACAATGGGTCGGACTGGA TGTCAACCACAGAAATGCCATTTTCTACTAGCGCTTTTCAAATACATAATGCGGAAAGGACTCCACTGAT GGACAATTGGTATTCATTATCATATCTGTACTTCAGTACTATTGGAACGCTGACAACACTGTTTGTGGGG ATACTTATCAGCTTATCAACAGGAGGAAGAAAACAGAACTTAGACCCCCGATTCTTACTAACCAAACAGG ACTTTTTATCCAATTTTGATGTTTTTAAGAAAAGGAATCATGTTTTAAACTATAAATTGCATCCTGTGGA AGTTGGTGGAAATGATAACCCTGCCTTCAACCATGTTGAGCTGAACTTCACAGATCACAGTGGCAAGATC AATGGGACTCGCTTG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG208933 representing BC017691
Red=Cloning site Green=Tags(s) MGGRSMSAVPVALSLTASFMSAVTVLGTPAEVYRFGAIFSIFVITYFFVVVISAEVFLPVFYRLGITSTY EYLELRFNRCIRLCGTILFIVQTILYTGIVIYAPALALNQVTGFDLWGAVVATGVVCTFYCTLGGLKAVV WTDVFQVGIMVAGFASVIIQASITQHGINKILSDAFNGGRLNFWNFDPNPLQRHTFWTIVIGGTFTWTTI YGVNQSQVQRYISCKSRLHAKLSLYVNLVGLWVILTCSIFCGLALYSRYRECDPWTSKKVSAIDQLMPYL VLDILKNYPGVPGLFVACAYSGTLSTVSSSINALAAVTVEDLIKPRFKSLSEKSLSWISQGMSVLYGALC IGMAALASLMGALLQAALSIFGMVGGPLLGLFSLGILVPFANSIGALTGLLAGFAISLWVGIGAQLYPPL PERTLPLPLETYGCNITHNGSDWMSTTEMPFSTSAFQIHNAERTPLMDNWYSLSYLYFSTIGTLTTLFVG ILISLSTGGRKQNLDPRFLLTKQDFLSNFDVFKKRNHVLNYKLHPVEVGGNDNPAFNHVELNFTDHSGKI NGTRL TRTRPLE - GFP Tag - V |
| Restriction Sites | SgfI-MluI Cloning Scheme for this gene |
| ACCN | BC017691 |
| ORF Size | 1695 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC017691.1 |
| RefSeq Size | 5351 bp |
| RefSeq ORF | 1697 bp |
| Locus ID | 216225 |
| Gene Summary | Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)-dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D-lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5-aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. Mediates iodide transport from the thyrocyte into the colloid lumen through the apical membrane. May be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract. May play a critical role in the entry of L-lactate and ketone bodies into neurons by a process driven by an electrochemical Na(+) gradient and hence contribute to the maintenance of the energy status and function of neurons.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC218578 | Slc5a8 (untagged) - Mouse solute carrier family 5 (iodide transporter), member 8 (cDNA clone MGC:19357 IMAGE:4239161), (10ug) |
CNY 6940.00 |
|
| MR208933 | Slc5a8 (Myc-DDK-tagged) - Mouse solute carrier family 5 (iodide transporter), member 8 (cDNA clone MGC:19357 IMAGE:4239161) |
CNY 4208.00 |
|
| MR208933L3 | Lenti ORF clone of Slc5a8 (Myc-DDK-tagged) - Mouse solute carrier family 5 (iodide transporter), member 8 (cDNA clone MGC:19357 IMAGE:4239161) |
CNY 5130.00 |
|
| MR208933L4 | Lenti ORF clone of Slc5a8 (mGFP-tagged) - Mouse solute carrier family 5 (iodide transporter), member 8 (cDNA clone MGC:19357 IMAGE:4239161) |
CNY 5130.00 |
