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Traip (NM_011634) Mouse Tagged ORF Clone
CAT＃: MG207523
- TrueORF®
Traip (tGFP-tagged) - Mouse TRAF-interacting protein (Traip)
ORF Plasmid: DDK
"NM_011634" in other vectors (4)
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CNY 3,710.00
Product images
Specifications
| Product Data | |
| Type | Mouse Tagged ORF Clone |
| Tag | TurboGFP |
| Synonyms | Trip |
| Vector | pCMV6-AC-GFP |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MG207523 representing NM_011634
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGCCTATCCGCGCTCTGTGCACTATCTGCTCCGACTTCTTCGATCACTCCCGTGACGTGGCTGCCATCC ACTGTGGCCACACTTTTCATCTGCAATGCCTAATCCAGTGGTTTGAGACAGCACCAAGTCGGACCTGCCC ACAGTGTAGAATCCAGGTTGGCAAAAAGACTATTATAAACAAACTTTTCTTTGACCTCGCCCAGGAAGAG GAGAATGTCTTGGATGCAGAATTCTTAAAGAATGAACTGGACAGCGTCAAAGCTCAGCTTTCCCAGAAAG ACAGGGAGAAACGGGACAGCCAGGCCATTATCGACACTCTACGGGACACCCTGGAAGAACGCAATGCTAC TGTGGAGTCCCTACAGAACGCCTTAAACAAGGCAGAGATGCTGTGTTCCACCCTGAAAAAACAGATGAAG TTCCTGGAGCAGCGGCAGGATGAGACCAAACAAGCTCGGGAGGAGGCCCACCGACTCAAGTGCAAGATGA AAACCATGGAGCAAATTGAGCTCCTACTCCAGAGCCAGCGGTCTGAGGTGGAGGAGATGATTCGAGACAT GGGTGTGGGACAGTCAGCGGTGGAGCAGCTGGCTGTGTACTGCGTGTCCCTCAAGAAAGAGTATGAGAAT CTGAAGGAAGCTCGGAAGGCCACAGGGGAACTGGCTGACAGGTTGAAGAAGGATTTGGTGTCCTCTAGGA GTAAGTTGAAGACTCTCAACACTGAGCTGGATCAGGCCAAGTTAGAACTGAGGTCAGCCCAGAAGGACTT ACAAAGTGCTGACCAGGAGATCATGAGCCTAAGAAAGAAGCTGATGATCCTCCAGGGAACCTTGAGCCTG CCTCCGGCGACCAATGAGACGGTCAGCCGCCTGGTTTTTGAGAGCCCAGCCCCTGTGGAGATGATGAACC CGAGGCTTCACCAGCCACCCTTCGGTGATGAGATTGATCTCAATACCACCTTTGATGTAAATACCCCTCC AACCCAGACCTCTGGCTCCCAGCATTGCCTCCCCAAGAAGCTGTGCCTGGAGAGGGCACGCTCTCCCATG CAGAATGTCCTCAAGAAGGTGCACAAAGTCTCCAAGCCGGAGTCCCAGCTCTCACTGGGTGGCCAGCGAT GTGTAGGAGAGCTAGATGAGGAACTGGCTGGTGCCTTCCCTCTCTTCATCCGGAATGCTGTCCTGGGTCA GAAACAGCCCAACAGGACCACAGCAGAATCCCGTTGCAGCACAGATGTGGTAAGAATAGGCTTTGATGGG CTTGGAGGACGAACAAAATTCATCCAGCCTAGGGACACAACCATTATCCGACCAGTGCCTGTTAAGTCCA AGGCCAAGAGTAAACAGAAAGTGAGAATAAAGACTGTGAGTTCTGCCTCCCAGCCCAAGCTGGATACCTT TTTATGTCAG ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG207523 representing NM_011634
Red=Cloning site Green=Tags(s) MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSRTCPQCRIQVGKKTIINKLFFDLAQEE ENVLDAEFLKNELDSVKAQLSQKDREKRDSQAIIDTLRDTLEERNATVESLQNALNKAEMLCSTLKKQMK FLEQRQDETKQAREEAHRLKCKMKTMEQIELLLQSQRSEVEEMIRDMGVGQSAVEQLAVYCVSLKKEYEN LKEARKATGELADRLKKDLVSSRSKLKTLNTELDQAKLELRSAQKDLQSADQEIMSLRKKLMILQGTLSL PPATNETVSRLVFESPAPVEMMNPRLHQPPFGDEIDLNTTFDVNTPPTQTSGSQHCLPKKLCLERARSPM QNVLKKVHKVSKPESQLSLGGQRCVGELDEELAGAFPLFIRNAVLGQKQPNRTTAESRCSTDVVRIGFDG LGGRTKFIQPRDTTIIRPVPVKSKAKSKQKVRIKTVSSASQPKLDTFLCQ TRTRPLE - GFP Tag - V |
| Restriction Sites |
SgfI-MluI
Cloning Scheme for this gene
Plasmid Map
|
| ACCN | NM_011634 |
| ORF Size | 1410 bp |
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_011634.3, NP_035764.2 |
| RefSeq Size | 2697 bp |
| RefSeq ORF | 1413 bp |
| Locus ID | 22036 |
| UniProt ID | Q8VIG6 |
| Gene Summary | E3 ubiquitin ligase acting as a negative regulator of innate immune signaling. Inhibits activation of NF-kappa-B mediated by TNF. Negatively regulates TLR3/4- and RIG-I-mediated IRF3 activation and subsequent IFNB1 production and cellular antiviral response by promoting 'Lys-48'-linked polyubiquitination of TNK1 leading to its proteasomal degradation (By similarity) (PubMed:17544371, PubMed:22945920). Involved in response to genotoxic lesions during genome replication. Promotes H2AX and RPA2 phosphorylation after replication-associated DNA damage and assists fork progression at UV-induced replication-blocking lesions during S phase. Might also play a role in promoting translesion synthesis by mediating the assembly of 'Lys-63'-linked poly-ubiquitin chains on the Y-family polymerase POLN in order to facilitate bypass of DNA lesions and preserve genomic integrity. The function in translesion synthesis is controversial (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC200902 | Traip (untagged) - Mouse TRAF-interacting protein (Traip), (10ug) |
CNY 2,000.00 |
|
| MR207523 | Traip (Myc-DDK-tagged) - Mouse TRAF-interacting protein (Traip) |
CNY 3,330.00 |
|
| MR207523L3 | Lenti ORF clone of Traip (Myc-DDK-tagged) - Mouse TRAF-interacting protein (Traip) |
CNY 5,230.00 |
|
| MR207523L4 | Lenti ORF clone of Traip (mGFP-tagged) - Mouse TRAF-interacting protein (Traip) |
CNY 5,230.00 |
