Naip2 (NM_001126182) Mouse Untagged Clone
CAT＃: MC224482
Naip2 (untagged) - Mouse NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 2, (10ug)
CNY 18620.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | Birc1b; Naip-rs6 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224482 representing NM_001126182
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCAGCCCAGGGAGAAGCCGTTGAGGAGATAATTTGTGAGTTTGATGACGACTTGGTCTCTGAGCTCT CTACTCTTCTCAGAGTGGATGCACTTTCAGTCTTGAAGAGACAACAAGAAGAAGACCATAAAACACGAAT GAAAATGAAGAAAGGTTTTAACTCACAGATGCGCAGTGAAGCCAAACGACTAAAGACTTTTGAGACCTAT GACAAGTTCAGATCATGGACGCCACAGGAGATGGCAGCTGCTGGGTTTTACCACACAGGGGTGAAACTTG GGGTTCAGTGCTTTTGCTGTAGCTTGATCCTCTTTTCCACCAGACTCAGGAAACTTCCCATAGAGAACCA CAAGAAATTACGACCAGAATGTGAGTTCCTTCTGGGCAAAGATGTTGGTAACATTGGCAAGTATGACATC CGGGTTAAGAGTCCAGAGAAGATGCTGAGAGGTGACAAAGCAAGGTACCATGAAGAGGAGGCAAGACTGG AGTCCTTTGAGGACTGGCCATTTTATGCCCATGGGACATCACCACGTGTACTCTCAGCAGCTGGCTTTGT CTTTACAGGTAAAAGGGACACTGTGCAGTGTTTCTCCTGTGGTGGATGCTTGGGCAACTGGGAAGAAGGA GATGATCCCTGGAAGGAGCATGCCAAGTGGTTCCCCAAATGTGAATTTCTTCAAAGTAAGAAGTCCCCAG AGGAAATTACCCAATATGTACAAAGCTATGAAGGATTTCTTCATGTAACGGGAGAACATTTTGTGAATTC CTGGGTCAGAAGAGAATTACCTATGGTATCAGCTTACTGCAATGACAGCGTCTTCGCTAATGAAGAACTA AGGATGGACACGTTTAAGGACTGGCCCCACGAATCACCCGGGGCTGTTGAAGCTCTGGTCAAAGCAGGCC TTTTCTACACAGGCAAAAGGGACATTGTCCAGTGTTTTTCCTGTGGAGGATGTATGGAGAAGTGGGCAGA AGGTGACAACCCAATAGAAGATCACACCAAGTTTTTTCCCAACTGTGTGTTTCTCCAAACCCTGAAGTCC TCTGCAGAAGTGATTCCAGCCCTTCAGAGCCACTGTGCACTTCCAGAAGCCATGGAAACCACAAGTGAAA GCAACCATGATGATGCAGCAGCAGTTCATTCTACAGTGGTGGATGTTTCTCCAAGTGAAGCCCAGGAACT TGAACCTGCATCCAGCTTGGTGTCTGTTCTCTGTAGAGACCAGGACCACAGTGAAGCCCAAGGGCGTGGA TGTGCATCCAGTGGGACCTATCTTCCCTCCACAGACTTGGGTCAGAGTGAAGCCCAGTGGCTTCAAGAGG CCAGGAGTCTGAGTGAGCAGCTGAGAGACACCTACACCAAAGCTACTTTCCGCCACATGAACTTGCCAGA AGTGTACTCCAGCCTCGGCACTGACCATTTGCTCAGCTGCGATGTGTCCATCATTTCAAAGCACATCAGC CAGCCAGTGCAAGGGTCCCTGACGATCCCTGAGGTCTTCTCCAATCTCAACTCTGTCATGTGTGTGGAGG GGGAAGCTGGCAGTGGAAAGACAACCTTCCTGAAGAGGATAGCTTTTCTCTGGGCATCAGGATGCTGCCC CCTGTTGTACAGGTTCCAGCTGGTCTTCTACCTCTCCCTTAGTTCCATCACACCAGGCCAGGAACTGGCC AAAATCATCTGTGCCCAACTCCTAGGGGCAGGAGGCTGCATTAGTGAAGTGTGTCTGAGCAGCATCATCC AGCAGTTACAACACCAGGTGCTGTTCCTGTTGGATGACTACAGTGGGCTGGCCTCACTCCCCCAAGCCCT ACACACACTGATTACAAAAAACTACTTGTCACGGACCTGCTTATTGATCGCTGTGCATACAAACAAGGTC AGGGGCATCCGCCCATACCTAGATACGAGTCTAGAGATCAAAGAGTTTCCCTTCTATAATACTGTCTCTG TGTTACGGAAGCTTTTTTCACATGACATAATGCGTGTACGAAAATTTATAAATTACTTTGGATTTCATGA AGAGTTGCAGGGAATTCACAAGACACCCCTCTTCGTGGCAGCAGTATGTACTGACTGGTTTAAAAATCCA TCTGACCAGCCCTTTCAGGATGTGGCACTTTTCAAGGCCTATATGCAATACTTGTCCTTAAAGCACAAAG GTGCAGCTAAGCCTCTCCAGGCCACAGTGTCCTCATGTGGGCAGCTGGCCTTGACAGGGCTTTTCTCATC GTGCTTTGAGTTCAATAGTGATAACCTGGCAGAGGCAGGAGTTGATGAAGATGAAGAGCTCACCACCTGC TTGATGAGCAAATTCACCGCCCAGAGACTGAGGCCAGTCTACCGGTTTTTAGGTCCTCTGTTCCAGGAGT TTCTTGCTGCCGTGAGGTTGACTGAACTCCTGAGTTCAGATAGGCAGGAAGACCAAGATCTGGGACTTTA TTATTTGAGACAAATTAACTCACCTCTAAAGGCTATGAGCATCTACCACACTTTTTTGAAATATGTCTCC AGCCACCCTTCATCAAAGGCAGCGCCAACAGTTGTATCTCATTTGCTTCAGTTGGTGGATGAGAAAGAGT CACTGGAGAACATGTCTGAAAATGAGGATTACATGAAGCTCCATCCAGAAGCTTTGCTGTGGATTGAGTG TCTTAGAGGATTGTGGCAGCTGTCTCCTGAATCTTTTTCTTTGTTCATTTCAGAAAACTTATTGCGCATT TGTCTAAACTTTGCTCATGAAAGCAACACAGTTGCTGCATGTTCTCCAGTTATTTTGCAGTTCCTTCGAG GGAGAACACTGGATTTGAAAGTTTTGAGTTTACAGTACTTTTGGGACCATCCAGAAACCTTGTTGTTATT GAAGAGTATTAAGATCTCATTAAATGGAAATAACTGGGTACAGAGAATCGATTTTTCACTCATAGAAAAA TCTTTTGAAAAAGTACAGCCACCAACTATAGATCAGGACTATGCCATTGCCTTTCAACCTATAAATGAAG TCCAGAAAAATTTATCTGAAAAGAAACACATAATAAAGAAGTATGAGGATATGAAACACCAGATCCCACT AAATATTAGTACTGGCTACTGGAAACTGTCCCCCAAGCCATACAAGATCCCCAAGCTGGAAGTTCAAGTG ACCAACACAGGTCCAGCAGATCAAGCACTGCTCCAGGTCCTCATGGAAGTCTTCTCAGCTTCACAGAGTA TTGAGTTCCGTTTATCCGACAGCAGTGGCTTCCTTGAAAGCATCCGCCCAGCTCTGGAGCTGAGTAAGGC CTCTGTCACCAAGTGTTCCATGTCCAGGCTGGAGCTCAGCAGAGAAGATCAGAAGCTGCTTCTCACCCTG CCTACCCTGCAGTCTCTCGAGGTCTCAGAGACAAACCAGTTACCAGATCAGCTCTTCCATAACTTGCACA AGTTCCTGGGCCTGAAAGAACTGTGTGTGAGACTAGATAGCAAGCCGGATGTGCTCTCAGTCCTTCCTGG AGAGTTCCCAAACCTCCATCACATGGAGAAGTTATCCATCAGAACCTCCACGGAGTCTGACCTCTCCAAA CTAGTTAAGTTGATTCAGAACTCTCCAAATCTCCATGTTTTCCATCTGAAGTGTAATTTCCTTTCGAATT GTGAGCCTCTCATGACTGTGCTTGCTTCCTGCAAGAAACTCAGAGAGATTGAGTTTTCTGGACGATGCTT TGAAGCCATGACCTTTGTCAACATTTTGCCAAATTTTGTTTTTCTGAAGATATTGAATCTTAGAGACCAA CAATTCCCAGATAAAGAAACATCAGAAAAGTTTGCCCAGGCTCTGGGTTCTCTCAGGAACCTGGAGAAAC TGTTCGTTCCCACTGGGGACGGGATTCACCAAGTGGCCAAACTGATTGTCCGGCAGTGTCTGCAGCTCCC ATGTCTCCGAGTTCTTGTCTTTGCAGAGACTCTGGATGACGACAGTGTACTGGAAATTGCCAAGGGAGCA ACCAGGGGAGGCTTCCAAAAACTTGAGAACTTAGACCTTACACTGAATCACAAGATTACAGAGGAAGGAT ACAGAAATTTCTTTCAAGTCCTGGACAACCTGCCAAACCTGAAAAACCTGGACATTTCCAGGCATATCCC AGAATGCATTCAAATTCAGGCCATCACTGTCAAGGCTCTGGGTCAGTGTGTGTCCCGACTGCCCAGCCTC ACCAGGCTCGGGATGCTCAGTTGGCTCCTGGATGAAGAGGACATAAAAGTGATTAATGATGTGAAGGAAA GACACCCTCAGTCCAAACGCTTGACTGTTCACTGGAGGTGGGTAGTGCCATTCTCTCCTGTCATTCAGAA GTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001126182 |
| Insert Size | 4344 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001126182.2, NP_001119654.1 |
| RefSeq Size | 4782 bp |
| RefSeq ORF | 4344 bp |
| Locus ID | 17948 |
| UniProt ID | Q9QUK4 |
| Gene Summary | Sensor component of the NLRC4 inflammasome that specifically recognizes and binds type III secretion system (T3SS) rod proteins such as S.typhimurium (Salmonella) PrgJ and B.thailandensis BsaK from pathogenic bacteria. Association of pathogenic bacteria proteins drives in turn drive assembly and activation of the NLRC4 inflammasome, promoting caspase-1 activation, cytokine production and macrophage pyroptosis. The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria. The NLRC4 inflammasome senses Gram-negative bacteria such as L.pneumophila and P.aeruginosa, enteric pathogens S.typhimurium (Salmonella) and S.flexneri. Prevents motor-neuron apoptosis induced by a variety of signals.[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG217659 | Naip2 (tGFP-tagged) - Mouse NLR family apoptosis inhibitory protein 2 (Naip2) transcript variant 2, (10ug) |
CNY 11880.00 |
|
| MR217659 | Naip2 (Myc-DDK-tagged) - Mouse NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 2 |
CNY 9904.00 |
|
| MR217659L3 | Lenti ORF clone of Naip2 (Myc-DDK-tagged) - Mouse NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 2 |
CNY 12730.00 |
|
| MR217659L4 | Lenti ORF clone of Naip2 (mGFP-tagged) - Mouse NLR family, apoptosis inhibitory protein 2 (Naip2), transcript variant 2 |
CNY 12730.00 |
