Ibtk (NM_001081282) Mouse Untagged Clone
CAT＃: MC224307
Ibtk (untagged) - Mouse inhibitor of Bruton agammaglobulinemia tyrosine kinase (Ibtk), (10ug)
CNY 17290.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 5430411K16Rik; AA409502; BTKI; mKIAA1417 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224307 representing NM_001081282
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGATGCTGCCACCCCCGACTGCACGTCAAAATGCAGATCCCTGAAGCATGCGCTGGATGTCCTTTCTG TGGTGACAAAGGGGAGTGAGAGCCAGATCAAGTCCTTCCTCGCCAGGTACTGCTACAATGCTGCAACTGT CAAGGATGCCTTTGGCAGGAACGCCGGCCACCTGGCTTCCTCCTGCGGGAAGAAAGGAGTGTTGGACTGG CTGATTGAGAAAGGAGTGGACTTGCTGGTGAAAGACAAGGAGTCCGGCTGGACAGCACTGCACAGAAGCG TTTTTTATGGACATATCGATTGTGTTTGGTCTCTGTTGAAGCATGGTGTTAGCTTGTATATGCAAGATAA AGAAGGATTGTCACCTTTGGATCTTCTTATGAAGGACAGGCCAACTCATGTTGTATTTAAGGACACTGAT CCCACAGAAGTCTATACTTGGGGAGATAACACAAACTTCACTCTGGGCCACGGAAGCCAGAATAGCAAAC ATCACCCCGAGCTGCTGGACCTGTTCTCCAGGAGTGGGGTTTATGTCAAGCAGGTGGTGCTTTGCAAATT TCATTCGGTGTTTCTGTCCCAGAAAGGGCAGGTTTACACCTGTGGCCATGGTCGCGGAGGACGGTTAGGC CATGGAGATGAACAGACATGCTTGGTTCCCAGGCTTGTGGAAGGACTGTCTGGTCACAATTGTTCGCAAG TGGCAGCTGCTAAGGATCACACTGTTGTGTTAACTGATGATGGATGTGTCTATACATTTGGTCTCAACAT GTTTCACCAATTAGGAATTATTCCTCCACCTGCTAGTTGTAATGTACCCAGACAGATACAGGCAAAATAT CTGAAAGGAAGGACTATCATTGGAGTAGCAGCGGGCAGGTTTCATACGGTGCTGTGGACTCGAGAAGCCG TTTACACACTGGGACTGAATGGTGGACAGTTGGGTCACTTACTGGATCCCAATGGTGAAAAGTGTGTCAC AACCCCTCGCCAAGTCTCTGCCCTTCATCACAAGGATATCGCTGTGTCTTTGGTAGCTGCAAGTGATGGT GCCACAGTCTGTGTCACCACAAGGGGAGACATTTACTTACTTGCAGACTATCAGTGCAAGAAGATGGCAA CTAAACAACTGAACTTGAAAAAGGTTCTTGTCTCTGGAGGTTGTATGGAATACAAGGTTGATCCTGAACA TTTGACAGAAAATGGAGGTCAGAAAATATGTGTCCTCGCTATGGATGGAGCTGGAAGGGTGTTTTGCTGG AGATCAATCAGCAGTTCTCTGAAGCAGTGCCGATGGGCCTATCCTCGCCAGGTGTCAATCTCCGATATTG CTTTAAATAGAAATGAAATTCTGTTTGTCACACAGGATGGGGAAGGATTTAAAGGGAAATGGTTTGAAGA CAAAAGAAAGAATTCTGAAAAGAAAGCAGACATTTTACCAAACCTCCATCATTCCTCATCAGATGTGTCT TGTGTCCCTGATACAAATAGTGTGTATGAAAGAATTCGACTTGAGAAACTTCCTTTTGCCCATAGAGCTG TTAGTGTCAGCACAGATCCAAGTGGGTGCAACTTTGCAATCCTACAGTCAGACCCTAAAACAAGCCTTTA TGAGATTCCAGTTGTGTCTTCATCATCTTTTTTTGAAGAATTTGGCAAGCTCCTGAGGGAGACAGATGAA ATGGACAGCTTCCACGATGTGACCTTTCAAGTTGGCAATAGACACTTCCCCGCACATAAATACATTTTGG CCGTGCGCTCTGACTTCTTCCAGAAGTTGTTTCTTTCAGATGGCTCTTCTTTAGAGCTGACGGATGTTTA CCAGAAAGACGAAGATGCTGCTGGCTGCCATCTCTTTGTGGTGGAGAAAGTCCATCCTGACTTGTTCGAA TACCTCTTACAGTTCATGTACACAGATACCTGTGACTTGTTAACTCATGGCTTCAAACCAAGAATGATCG TGAAGAGAAAGGCAGAAGACTGTGAGGGCTCCCCAGATTCTCATCTGCACACTGTGAATTGCCATGTGGA TGATAAACAGAAGTCAGCATTTGAGGTGTACAGAAGCAACCAGGCCCACACACTTAGTGAACGGCAGAAG AGCAAACCCAAATCTTCTAAGAAGGGAAAAGGTGTTGGGGACGACGACCCTGTAAGGATGTTGCAAAGTG TTGCTAAGAAGTTTGGCCTCAGTAATTTGAGTAGCAGGTTAGAAGGAGTCAGATTGGAAAATGAAAAAAT TAATGTTATTGCGAAGAAAACTGGCAATAAACTGAAGCTAAGTCAGAAAAAATGTTCGTTTCTGTATGAT GTCACCATGAAGTCTGTGGATGGAAAGGAGTTCTCCTGCCATAAGTGTGTGCTCTGTGCGAGACTTGAGT ATTTCCACAGCATGCTTAGCAGATCGTGGATTGAGGCCTCCAGCTGTGCAGCTCTGGAAATGCCAATCCA GTCTGAGATTCTGAAAGTGATTTTGGACTACCTCTACACTGATGAGGCTGTGGTGATAAAAGAGTCTCAA AACGTGGACTTTGTTTGTAGTGTTCTTGTCGTGGCTGATCAGCTTCTCATAACTCGGTTAAAGGAGATTT GTGAAGTAGCATTGACTGAAAACCTTACCCTTAAGAATGCTGCGATGCTGCTGGAGTTTGCAGCCTTGTA CAATGCTGGGCAGTTGAAGCTCTCTTGTTTACAGTTCATAGGACTGAATATGGCAGCTTTACTTGAAGCA AGGTCTCTGGATGTTTTAAGTGAGGATGTTTTGAAGGACCTTTCCATATTCTACAGAAAAATGATTCCAG CAATGGAGAGAAGAGTCATTACACCGTATCAAGATGGGCCAGATATTAGCTCTATGCAAGTAGAAGACGG AGAGGTCTTTTTTAAAGAAGAAATAAACATGGAACCAAATTACTCGGAAACTATGTTCAAGAAGGCGAAA ACAAGAGCTAAAAAGAAGCCACGGAAGCGCTCAGACAGTTCAGGAGGCTACACCCTTTCAGATGTTATCC AGAGTCCACCGTCTGCAGGATTATTAAAGTCTGCAAAGACCAATTCTGTGGAGTCTCTTCCAGAATTGTT GACCTCAGATTCGGAAGGAAGCTATGCAGGAGTGGCGAGTCCCAGAGACCTCCAGTCGCCCGACTTCACA GCAGGATTCCATTCGGATAAGGTCGAGGGGAAAGCTAAGCCATACGTGAATGGTATACCTCCTCCATGTA CTAGGGAAGATGTAAAGCCGTGGGAGAAATCACCAACAACTAAGTCTGCTCCCCAGTTCATCCCCAGTAA CAGAGTGGACACTGCAGCCTCTTCCAGTTGGCTTGCCGGCTCTTGCAGTCCTGTGAGTCCTCCTGTTGTG GATCTTAGAACCATCATGGAAACAGAAGAAAACAGACAGAAATATGGCGCAGCACCAAAGTCAAACTTAG GAAAGATTATTTCTCACGGAATCAAACTTTCTCAGAAGCAACGGAAAATGATTGCATTGACCACCAAAGA AAACAATTCAGGAACGAACAGCATGGAAGCCATTTTGACAGCTCCTTCCAAGTCCCCCAAGCCTGCGAAT GCATGGGCACCTCTGCACTCACCTTTATCCAGGTCATTCCGGGATTTTTTACTAGAAGAAAAAAAACCCG TTCCTGGCTATGGTTCAGGAGATCATGTCAAAAAAGTTTGTTTTAAAGGAACTGAAAACTCTCCAGCCCT AAATGTTGCAAGATGTTCAACCCATGGAACTCCAGGATTAGAAAGCAATCATGTTTCTGATTTTCCACTT CTAGACAGTCCCAACCCCTGGCAGTCTTCCTCCCTGGCGGCTTCTCCCGCAGTTGCTCCAGTCACATTTG CATCCATTGTAGAAGAAGAGCGGCAACAAGAAGCTGCCCTCATCAGAAGCCGGGAGAAACCCTTGGCTCT CATTCAGGTCGAGGAGCATGCAATACAAGACTTGCTGGTTTTCTATGAGGCATTTGGCAACCCCGAGGAG TTTGTCGTCGTTGAAAGGGCACCACAGGGGCCTCTGGCAGTGCCTATGTGGAACAAGCATGGCTGCTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001081282 |
| Insert Size | 4059 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001081282.2, NP_001074751.1 |
| RefSeq Size | 5679 bp |
| RefSeq ORF | 4059 bp |
| Locus ID | 108837 |
| UniProt ID | Q6ZPR6 |
| Gene Summary | Acts as an inhibitor of BTK tyrosine kinase activity, thereby playing a role in B-cell development. Down-regulates BTK kinase activity, leading to interference with BTK-mediated calcium mobilization and NF-kappa-B-driven transcription (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) encodes the longer protein (isoform 1). |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG224109 | Ibtk (tGFP-tagged) - Mouse inhibitor of Bruton agammaglobulinemia tyrosine kinase (Ibtk), (10ug) |
CNY 12920.00 |
|
| MR224109 | Ibtk (Myc-DDK-tagged) - Mouse inhibitor of Bruton agammaglobulinemia tyrosine kinase (Ibtk) |
CNY 9248.00 |
|
| MR224109L3 | Lenti ORF clone of Ibtk (Myc-DDK-tagged) - Mouse inhibitor of Bruton agammaglobulinemia tyrosine kinase (Ibtk) |
CNY 13680.00 |
|
| MR224109L4 | Lenti ORF clone of Ibtk (mGFP-tagged) - Mouse inhibitor of Bruton agammaglobulinemia tyrosine kinase (Ibtk) |
CNY 13680.00 |
