Atp8b1 (NM_001001488) Mouse Untagged Clone
CAT＃: MC224062
Atp8b1 (untagged) - Mouse ATPase, class I, type 8B, member 1 (Atp8b1), (10ug)
CNY 16060.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AI451886; FIC1; Ic |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC224062 representing NM_001001488
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGAGCACAGAAAGAGACTCGGAAACAACATTTGATGAGGAGTCTCAGCCCAACGATGAAGTGGTCCCCT ACAGTGATGATGAAACTGAAGACGAACTTGAAGATCAGGGGTCCACGGTTGAACCAGAACAGAATCGTGT CAACAGAGAAGCTGAGAAGAAGAGAGAGACATTCCGGAAAGATTGCACGTGGCAAGTCAAAGCAAATGAC CGAAAGTTCCACGAACAACCTCATTTCATGAACACCAAGTTCTTTTGTATTAAGGAGAGCAAATATGCGA GTAATGCAATTAAAACATACAAGTACAATGGATTTACCTTTCTACCCATGAATTTGTTTGAGCAGTTTAA GAGGGCAGCCAACTTCTATTTCCTCATCCTCCTGATCCTGCAGGCAATTCCTCAAATCTCCACCCTGGCA TGGTATACCACACTTGTACCTCTGCTTTTGGTGCTGGGCATCACGGCCATCAAAGACCTGGTAGATGATG TGGCTCGTCATAAAATGGACAAGGAAATCAACAATAGGACGTGTGAAGTCATTAAGGATGGCAGGTTCAA AATCATCAAGTGGAAAGATATCCAGGTTGGAGATGTCATCCGCCTGAAGAAGAATGATTTTATTCCAGCT GACATCCTGCTGTTGTCCAGTTCAGAGCCTAACAGCCTCTGCTATGTAGAAACGGCTGAGCTCGACGGAG AAACCAATTTGAAGTTCAAAATGGCCCTGGAAATCACGGACCAATATCTCCAAATAGAAGATAACTTGGC AACATTTGATGGTTTCATCGAATGTGAAGAACCAAACAATCGGTTAGACAAGTTCACAGGAACGCTGTTT TGGAAGAACCAAAGCTTTCCTTTGGATGCTGATAAAATCCTGTTACGAGGTTGTGTGATAAGGAACACCG ATGTCTGCCATGGCCTGGTCATTTTTGCAGGTGCTGACACAAAGATAATGAAGAATAGTGGGAAAACCAG ATTTAAAAGAACCAAAATTGATTACTTGATGAACTACATGGTGTACACGATCTTTATTGTTCTCATCCTG GTTTCTGCCGGCCTCGCCATTGGCCACGCCTATTGGGAAGCCCAAGTTGGCAATTATTCCTGGTACCTCT ATGATGGAGAAAATGCCACACCGTCCTACCGGGGATTCCTGAATTTCTGGGGCTACATCATTGTATTGAA CACCATGGTGCCCATTTCTCTCTATGTCAGTGTGGAAGTGATCCGTCTGGGACAGAGTCATTTCATCAAC TGGGACCTGCAGATGTACTATGCTGAGAAGGACACTCCTGCCAAGGCGAGGACCACCACCTTGAATGAGC AGCTAGGGCAGATTCATTACATCTTCTCTGATAAGACGGGGACACTCACGCAAAATATCATGACCTTCAA AAAGTGCTGCATTAACGGGACTATCTATGGAGACCATCGAGATGCTTCTCAACACAGCCACAGCAAAATC GAGCTAGTGGACTTTAGCTGGAATACATTTGCCGATGGAAAGCTTGCATTTTATGACCATTACCTTATCG AGCAAATACAGTCAGGGAAAGAGCCAGAAGTACGACAGTTCTTCTTTTTGCTTTCGATTTGCCATACGGT CATGGTGGACAGAATTGATGGTCAGATCAACTACCAGGCGGCTTCTCCTGATGAAGGCGCCCTGGTAAAC GCCGCCAGGAACTTCGGCTTTGCCTTTCTCGCCCGGACGCAGAACACCATCACCGTCAGCGAACTGGGCT CAGAGAGGACCTACAACGTCCTTGCCATTTTGGATTTCAACAGCGACCGAAAGCGGATGTCTATCATCGT GAGGACCCCAGAAGGTAGTATCCGGCTGTACTGTAAAGGTGCTGACACCGTGATTTATGAACGGCTCCAT CGGATGAATCCTACGAAGCAAGAAACACAGGATGCCCTGGATATCTTTGCAAGTGAGACTCTCAGGACCC TGTGCCTGTGCTACAAGGAAATTGAAGAAAAAGAATTTACAGAATGGAATAATAAGTTTATGGCCGCCAG CGTGGCCTCAAGCAACCGAGACGAAGCGTTGGATAAAGTGTACGAGGAGATTGAGAAAGACTTGATTCTC TTGGGAGCTACTGCTATTGAAGACAAGCTACAGGATGGAGTCCCAGAAACCATTTCAAAACTTGCAAAAG CTGACATTAAGATCTGGGTACTCACCGGAGACAAAAAGGAAACTGCAGAAAACATAGGTTTTGCCTGTGA ACTCTTGACGGAAGACACTACTATCTGCTACGGAGAGGACATAAACTCTCTTCTTCACACCAGGATGGAG AATCAGAGAAACAGAGGTGGAGTCTCTGCGAAATTTGCACCTCCTGTGTATGAACCCTTTTTTCCACCTG GAGAAAACCGTGCCTTAATCATCACTGGCTCCTGGCTGAATGAAATCCTTCTAGAGAAGAAGACCAAGAG AAGTAAGATCCTGAAGCTGAAGTTCCCAAGGACAGAGGAGGAGAGGCGGATGCGGAGCCAGAGCCGGAGA CGGCTGGAAGAGAAGAAAGAGCAGCGGCAAAAGAACTTCGTGGACCTGGCCTGCGAGTGCAGCGCCGTCA TCTGCTGCCGCGTCACGCCCAAGCAGAAGGCCATGGTGGTGGACCTGGTGAAGAGGTACAAGAAAGCCAT CACCCTGGCCATCGGAGACGGGGCCAATGATGTCAACATGATCAAAACTGCCCACATTGGTGTTGGAATA AGTGGACAAGAAGGGATGCAAGCTGTCATGTCCAGTGACTATTCTTTTGCTCAGTTCAGATATCTGCAGC GGTTGCTGCTGGTCCACGGCCGGTGGTCTTACATAAGGATGTGCAAGTTCCTACGATACTTCTTTTACAA GAACTTTGCCTTTACTTTAGTTCATTTCTGGTACTCCTTCTTCAATGGCTACTCAGCCCAGACGGCGTAT GAGGATTGGTTTATCACCCTCTACAACGTGCTGTACTCCAGTTTGCCTGTGCTCCTCATGGGGCTGCTGG ATCAGGACGTGAGTGACAAGCTGAGCCTCCGATTCCCTGGGCTGTATGTAGTGGGGCAGAGGGACTTGCT GTTCAACTATAAGAGATTCTTTGTCAGTTTGCTGCATGGGGTCTTAACCTCAATGGTCCTCTTCTTCATA CCGCTTGGTGCTTATCTGCAAACAGTGGGACAGGATGGGGAGGCGCCTTCAGACTACCAGTCCTTCGCCG TCACGGTGGCCTCCGCTCTAGTGATAACGGTCAACTTCCAGATTGGCTTGGATACTTCATACTGGACTTT TGTGAATGCCTTTTCAATTTTCGGCAGCATCGCACTGTACTTCGGCATCATGTTTGATTTCCACAGTGCT GGGATACACGTTCTCTTTCCGTCCGCATTTCAGTTCACAGGTACAGCTTCCAATGCCCTGAGACAGCCAT ACATCTGGCTGACCATCATCCTGACGGTTGCCGTGTGCTTACTACCTGTCGTCGCCATCCGTTTCCTGTC CATGACCATTTGGCCCTCAGAAAGTGATAAGATCCAGAAGCATCGAAAGCGATTGAAGGCTGAAGAGCAG TGGAAACGGCGGCAGAGCGTGTTCCGGAGGGGAGTATCTTCCAGGCGCTCAGCCTATGCCTTTTCGCATC AGAGAGGCTACGCAGACCTCATCTCCTCTGGCCGCAGCATCCGCAAGAAGCGCTCGCCCCTGGATGCCAT CATCGCGGATGGCACGGCTGAGTACCGGCGCACAGTGGAGAGCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001001488 |
| Insert Size | 3756 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001001488.3, NP_001001488.2 |
| RefSeq Size | 6440 bp |
| RefSeq ORF | 3756 bp |
| Locus ID | 54670 |
| UniProt ID | Q148W0 |
| Gene Summary | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. May play a role in asymmetric distribution of phospholipids in the canicular membrane. Plays a role in bile salt homeostasis. In cooperation with ABCB4 may be involved in establishing integrity of the canalicular membrane thus protecting hepatocytes from bile salts. Involved in the microvillus formation in polarized epithelial cells; the function seems to be independent from its flippase activity. Required for the preservation of cochlear hair cells in the inner ear. Required for the preservation of cochlear hair cells in the inner ear. According PubMed:20852622 is proposed to act as cardiolipin transporter during inflammatory injury; the function is questioned by PubMed:21475228.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG224089 | Atp8b1 (tGFP-tagged) - Mouse ATPase class I type 8B member 1 (Atp8b1), (10ug) |
CNY 12070.00 |
|
| MR224089 | Atp8b1 (Myc-DDK-tagged) - Mouse ATPase, class I, type 8B, member 1 (Atp8b1) |
CNY 13064.00 |
|
| MR224089L3 | Lenti ORF clone of Atp8b1 (Myc-DDK-tagged) - Mouse ATPase, class I, type 8B, member 1 (Atp8b1) |
CNY 12830.00 |
|
| MR224089L4 | Lenti ORF clone of Atp8b1 (mGFP-tagged) - Mouse ATPase, class I, type 8B, member 1 (Atp8b1) |
CNY 12830.00 |
