Jmy (NM_021310) Mouse Untagged Clone
CAT＃: MC222946
Jmy (untagged) - Mouse junction-mediating and regulatory protein (Jmy), (10ug)
CNY 12640.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA591059 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC222946 representing NM_021310
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTCGTTCGCGCTGGAGGAGACACTCGAGTCCGACTGGGTGGCGGTGCGGCCCCACGTATTCGACGAGC GCGAGAAGCACAAGTTTGTGTTCATTGTGGCCTGGAACGAGATCGAAGGCAAGTTTGCTATAACCTGTCA CAACCGGACGGCCCAGAGACAGAGGAGCGGTTCCCGGGAACAGGCGGGGACGCCCGCGTCTGATGGGAGT CGCGGTCCGGGCAGCCCCGCGGCCAGGGGTCGGTCAGAGGCCGCTGCCTCTGCTACAGCAGCGCTCCGGA GTCCCGGGCCACGGAAAAGCCAGGCCTGGGCCGAGGGCGGCTCTCCGCGCAGCGCGCGCAGCCTGAAGGG GGATCCTCCTCGGGGTCCCGCGGGCAGAGGACCGGAGAGTCCTCTCCGTAGCCCCGCGCGGGCTAAGGCC AGCCCGCTCCGCAGAAGCGCCGAATCCCGAGATGCGACCGCCAGTGCCACGCCAGCCCCGCCGGCGCCCC CGGTGCCCCCGGTGTCGTCGGTGCGGGTGGTGAGTGCCTCCGGGGCGGTCTCCGAGGAGATCGAGGTCCT GGAAATGGTGAGGGAGGACGAGGCGCCACAGCCGCTCCCGGACTCGGAGCAGCCGCCGTCTGCCGCGGAG CTGGAGTCTCCGGCCGAAGAATGCAGCTGGGCCGGGCTTTTCTCCTTCCAGGATCTGCGAGCCGTGCATC AGCAGCTGTGCTCGGTAAACTCCCAGCTGGAGCCGTGTCTGCCGGTGTTCCCCGAAGAGCCGTCAGGCAT GTGGACGGTGCTGTTTGGGGGCGCCCCCGAGATGACCGAGCAGGAGATCGACGCTCTATGTTACCAACTC CAGGTATACCTGGGCCACGGCCTGGACACGTGTGGCTGGAAGATCCTTTCTCAGGTTCTTTTCACCGAGA CGGATGATCCGGAGGAGTATTACGAAAGCCTCAGCGAGCTGCGGCAGAAGGGCTATGAAGAGGTGCTTCA GCGGGCCAGGAGGCGCATCCAGGAGCTCTTGGACAAGCACAAGACTATAGAAAGCATGGTAGAGCTTTTG GACTTGTATCAGATGGAGGATGAAGCCTACAGCAGCCTTGCAGAGGCCACAACTGAACTCTACCAGTATT TACTTCAGCCATTCCGAGACATGCGAGAACTGGCCATGCTACGAAGACAGCAGATCAAGATTTCCATGGA GAATGATTATTTGGGCCCTCGAAGAATTGAGAGTCTACAGAAAGAAGATGCTGACTGGCAGCGGAAAGCT CACATGGCTGTTTTGTCTATTCAGGATCTCACCGTCAAATATTTTGAAATAACAGCAAAAGCTCAGAAAG CTGTGTATGATCGGATGCGAGCAGATCAGAAGAAATTTGGCAAAGCATCGTGGGCAGCAGCTGCTGAGCG AATGGAAAAACTCCAGTATGCAGTTTCTAAAGAGACTTTGCAGATGATGAGAGCTAAAGAAATTTGTCTG GAACAGAAGAAACATGCACTAAAAGAAGAGATGCAAAGCTTACAGGGTGGTACAGAAGCTATAGCTCGAT TGGATCAGCTGGAATCTGACTACTATGATCTGCAACTTCAGTTGTATGAAGTACAGTTTGAAATCTTGAA GTGTGAAGAGTTGTTATTAACTGCACAGCTGGAGAGCATCAAGAGACTTATATCAGAAAAGAGAGATGAA GTGGTGTACTACGACACTTACGAAAGCATGGAGGCCATGCTGGAGAAGGAAGAGATGGCAGCGTCTGTGC ACGCCCAGAGGGAAGAGCTACAGAAACTGCAGCAGAAGGCACGCCAGCTGGAAGCAAGAAGGGGCCGTGT CTCAGCCAAGAAAGCCTACCTCAGAAATAAAAAAGAAATTTGCATTGCAAAACACCATGAGAAGTTCCAG CAGCGTTTTCAGAGTGAAGATGAATATAGAGCCCATCATACAATACAAATAAAGAGAGACAAATTGCATG ATGAAGAGGAAAGAAAAAGTGCCTGGGTTAGCCAAGAGAGACAGAGGACACTGGATAGACTTCGAACATT TAAGCAGAGGTACCCCGGGCAAGTCATCCTTAAGTCGACCAGATTACGAGTGGCGCATTCAAGAAGAAAA AGCACAGCAAGCCCTGTGCCCTGTGAGGAGCAGTGTCACTCTCTGCCAACAGTGCTGCAGGGGCAGGAGA AGACAGAGGTGGGAGGAGGAGGAAGCCAGCTTGGGCCTTCACAGACAGCAGAACCCCAGAGCCTTGTCCA ACTTGAAGACACTTCATCAGAACAACTTGAATCCACCTCATTACCTCCTCGTGCTGTCGTCAGCTCTGAA CTGCCTCCTCCACAGTCAGCTCCACTGTTGACTAGTATTGACCCCAAACCGTGTTCTGTTACTATAGATC CTCTCCCACCCCCTCTTCCTCCAACACCTCCCCCTCCCCCACCCCCACCCCCACCTCCACCCCCACCCCT GCCTGTTGCAAAGGACAATGGGGCCTCCACCACTGCAGAGACACTGGAGAAAGATGCACTTAGGACGGAG GGCAATGAGAGGAGCATCCCAAAGTCGGCCAGTGCCCCCGCAGCACACCTCTTTGATAGCAGCCAGCTGG TCAGCGCACGGAAAAAGCTCAGAAAGACTGTGGAAGGGCTGCAGAGGAGGAGAGTGAGTTCACCCATGGA TGAAGTGTTAGCATCCTTGAAGCGTGGTAGCTTTCATCTGAAAAAGGTTGAACAGCGGACTCTGCCTCCT TTTCCTGATGAAGATGATAGTAATAATATTTTGGCGCAGATAAGGAAAGGGGTAAAGTTGAAGAAGGTTC AGAAGGAAGTTTTGAGAGAATCCTTCACACTTCTGCCTGATACCGACCCTTTGACACGGAGTATCCACGA AGCTCTAAGAAGAATCAAAGAAGCGTCCCCAGAGTCAGAGGATGAGGAAGAGGCTTTGCCGTGCACAGAC TGGGAGAACTAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_021310 |
| Insert Size | 2952 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021310.3, NP_067285.2 |
| RefSeq Size | 8780 bp |
| RefSeq ORF | 2952 bp |
| Locus ID | 57748 |
| UniProt ID | Q9QXM1 |
| Gene Summary | Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211383 | Jmy (tGFP-tagged) - Mouse junction-mediating and regulatory protein (Jmy) |
CNY 7890.00 |
|
| MR211383 | Jmy (Myc-DDK-tagged) - Mouse junction-mediating and regulatory protein (Jmy) |
CNY 7200.00 |
|
| MR211383L3 | Lenti ORF clone of Jmy (Myc-DDK-tagged) - Mouse junction-mediating and regulatory protein (Jmy) |
CNY 9030.00 |
|
| MR211383L4 | Lenti ORF clone of Jmy (mGFP-tagged) - Mouse junction-mediating and regulatory protein (Jmy) |
CNY 9030.00 |
