Pde12 (NM_178668) Mouse Untagged Clone
CAT＃: MC219649
Pde12 (untagged) - Mouse phosphodiesterase 12 (Pde12), (10ug)
CNY 7790.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2'-PDE; E430028B21Rik |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219649 representing NM_178668
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGTGGAGGCTCCCGGGCCGCAGCGCGCTTCGTGGGGTCCGGTCGGTGGTGGAGCGGCGCAGCCGGGCCG AGGCAGGGACTCACGAGGCGGTGCGCGCCATGGAGCGCGCGGTGGTGCGCTGTGTGCCCTCGGAGCCCAA GCTCAGCCTGTCTTTCGCGTTGGCCGACGGCAGCCACAAAAACATGCAGAGGGACCAGAGCGAGCCTCTG GGCCGGGCCCTCAGCCGGATCGCTACCAACGCCCTCAAGGGACACGCAAAGGTAGCGGCCGCCAAGAAGA GCAGGAAGAACCGAGCCCACTCGAGCGGTGGCGCGGCCTGTGAGGCTACAGGGCCTGAGCCGGTTGCGAC CTGCGAGCCGGTGGTGAAGCTGTACTACCGGGAGGAGGCGGTGGCCGAGGATGTGCTCAATGTGGACGCC TGGCAGGACGGAGCGGTGCTGCAGATCGGCGACGTCAAGTACAAGGTGGAGCGCAACCCGCCCACCTTCA CGGAGCTGCAGTTGCCGCGCTACATCATGGCTGGCTTCCCTGTGTGCCCCAAACTCGGCGTGGAATTTGG GGATCCCGCCAGCTCCGTGTTCCGCTGGTACAAGGAAGTCAAACCCGGGGCGGCAGAACCTGGGGACAGC GGCCCCGCGTCCTCGTCTCACTCTTCGCAGCCTTCAGCTTGGATCGAGACCGGTGTGGACGAGCGCGTCT ACACCCCGTGCAATGCAGACATCGGGCTCCGGCTCCGGCTTCACTGTACACCGGGCAATGGGCAGCGCTT CGGGCCAAGCCGGGAGCTAGAAAGCCTGTGCCCGGTGGAGGCCGGGCCTGGCACCTGCACTTTTGACCAT CGACATCTGTACACCAAGAAGGTGACGGAGGACTCTTTCATCCGCACTGTCTCCTACAACATCCTGGCAG ACACGTACGCCCAGACTGAGTTCTCTCGGACGGTCTTGTACCCGTACTGTGCCCCCTACGCCCTGGAGCT TGACTACCGCCAGAATCTCATACAGAAGGAGCTCACAGGCTACAACGCAGACCTCATCTGTTTGCAGGAG GTGGACCGCGCGGTGTTCTCCGACAGCTTGGTACCGGCCCTGGAGGCCTTCGGGCTGGAGGGCGTGTTCC GAATCAAGCAGCACGAAGGCCTGGCCACTTTCTACCGGAAGTCCAAGTTCAGGCTCCTTAGTCAACATGA CATCTCTTTTCAAGAAGCCCTCAAGTCGGACCCACTGCACAAAGAATTACTAGAGAAGCTGGCTTTGAAC CCATTAGCACAGGAGAAGGTCCTCCAGAGGTCATCTGTCCTTCAGATTTCAGTTCTTCAGTCTACAACAG ACTCTTCCAAAAAGATATGTGTTGCTAATACCCATCTCTACTGGCACCCAAAAGGTGGATACATTCGTCT CATTCAAATGGAAGTAGCCTTGGTTCATATTAGACATGTCTCACGTGATCTCTATCCTGGCATACCAGTT ATATTTTGTGGAGACTTTAATAGTACACCATCAACAGGCATGTATCATTTTGTCATCAGTGGCAGCATTG CAGAGGATCATGAAGACTGGGCTTCCAATGGGGAAGAGGAGAGATGCAGCATGCCTCTCTCACACTGTTT CAAACTGAAGAGTGCTTGTGGTGAACCTGCCTACACAAATTATGTCGGTGGCTTTCACGGATGTCTAGAT TACATTTTCATTGACTTAAATACTTTAGAGGTTGAACAGGTGATTCCATTACCTAGTCATGAAGAAGTTA CCACCCACCAGGCCTTACCTAGTGTTTCTCATCCTTCTGATCACATAGCACTTGTATGTGACTTAAAATG GAAATAG ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_178668 |
| Insert Size | 1827 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_178668.3, NP_848783.3 |
| RefSeq Size | 3551 bp |
| RefSeq ORF | 1827 bp |
| Locus ID | 211948 |
| UniProt ID | Q3TIU4 |
| Gene Summary | Enzyme that cleaves 2',5'-phosphodiester bond linking adenosines of the 5'-triphosphorylated oligoadenylates, triphosphorylated oligoadenylates referred as 2-5A modulates the 2-5A system. Degrades triphosphorylated 2-5A to produce AMP and ATP. Also cleaves 3',5'-phosphodiester bond of oligoadenylates. Plays a role as a negative regulator of the 2-5A system that is one of the major pathways for antiviral and antitumor functions induced by interferons (IFNs). Suppression of this enzyme increases cellular 2-5A levels and decreases viral replication in cultured small-airway epithelial cells.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209382 | Pde12 (tGFP-tagged) - Mouse RIKEN cDNA E430028B21 gene (E430028B21Rik) |
CNY 5040.00 |
|
| MR209382 | Pde12 (Myc-DDK-tagged) - Mouse phosphodiesterase 12 (Pde12) |
CNY 4536.00 |
|
| MR209382L3 | Lenti ORF clone of Pde12 (Myc-DDK-tagged) - Mouse phosphodiesterase 12 (Pde12) |
CNY 6460.00 |
|
| MR209382L4 | Lenti ORF clone of Pde12 (mGFP-tagged) - Mouse phosphodiesterase 12 (Pde12) |
CNY 6460.00 |
