Ubqln4 (NM_033526) Mouse Untagged Clone
CAT＃: MC219551
Ubqln4 (untagged) - Mouse ubiquilin 4 (Ubqln4), (10ug)
CNY 7700.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | A1u; A1Up; AI663987; CIP75; UBIN |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC219551 representing NM_033526
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGAGCCGAGTGGGGCTGAGACGAGGCCCCAGATTCGGGTCACCGTCAAGACCCCCAAGGACAAGG AGGAGATCGTGATCTGCGATCAAGCCTCGGTCAAGGAGTTCAAGGAGGAGATCTCCCGGAGGTTTAAGGC TCAGCAGGATCAGCTGGTCCTGATCTTCGCAGGCAAGATCCTCAAGGATGGGGACACCCTGAGCCAGCAC GGCATCAAGGATGGGCTCACAGTCCACCTAGTCATCAAAACCCCTCAGAAGGCTCAAGATCCAGTGACTG CTGCTGCTTCTCCTCCATCCACTCCTGACTCTGCCTCTGCACCCTCCACCACGCCTGCCTCACCTGCCGC CGCCCCTGTCCAGCCCTGCAGCTCTGGCAATACAACTTCAGATGCTGGCAGTGGAGGGGGGCCCTCTCCA GTGGCTGCAGAGGGGCCCTCAAGTGCTACTGCATCGATCCTCTCTGGCTTCGGAGGCATCCTGGGACTGG GCAGCCTGGGCCTGGGCTCCGCCAACTTTATGGAGCTGCAGCAACAGATGCAGAGACAGCTCATGTCCAA TCCTGAGATGCTGTCGCAGATCATGGAGAACCCCTTGGTCCAGGATATGATGTCAAACCCTGATCTGATG CGCCACATGATCATGGCTAATCCCCAGATGCAGCAGCTGATGGAGAGGAACCCCGAGATCAGCCACATGC TCAACAACCCAGAGCTCATGAGGCAGACAATGGAGCTTGCTCGTAACCCAGCCATGATGCAAGAAATGAT GCGGAACCAGGACCGGGCCCTCAGCAACCTGGAAAGTGTCCCGGGAGGGTATAATGCCCTCCGCCGCATG TACACGGACATCCAGGAGCCCATGTTCACTGCTGCTCGGGAACAGTTTGGCAACAATCCCTTCTCTTCCC TGGCCGGGAACTCCGACAACTCATCCTCCCAACCTCTTCGGACTGAGAATCGAGAGCCCCTCCCTAACCC CTGGAGCCCCTCGCCCCCCACCTCCCAGGCCCCCGGGTCCGGTGGGGAGGGCACCGGAGGATCGGGGACC AGCCAGGTGCACCCGACAGTCTCGAACCCCTTTGGGATCAATGCGGCTAGCCTGGGGTCAGGGATGTTCA ACAGCCCAGAAATGCAGGCGCTCCTCCAGCAGATTTCTGAAAACCCCCAGCTGATGCAGAATGTCATCTC AGCCCCTTACATGCGCACCATGATGCAGACGCTTGCCCAGAACCCTGACTTTGCTGCTCAGATGATGGTG AATGTGCCGCTGTTCGCAGGGAATCCACAGCTTCAGGAGCAGCTCCGCCTGCAGCTCCCCGTGTTTCTGC AGCAGATGCAAAACCCAGAGTCTCTCTCCATCCTCACCAATCCCCGGGCCATGCAGGCCCTGCTGCAGAT CCAGCAGGGACTACAGACCCTCCAGACTGAAGCCCCTGGGCTGGTACCCAGCCTTGGCTCCTTTGGGACA CCCCGGACCTCGGTACCTCTGGCAGGCAGCAACTCTGGATCTTCGGCAGAGGCCCCCACTTCTTCCCCGG GCGTGCCAGCCACATCTCCTCCCAGTGCGGGTTCCAATGCCCAGCAACAACTCATGCAGCAGATGATCCA ACTTTTGTCCGGAAGTGGGAACTCACAGGTGCCGATGCCAGAAGTGAGATTTCAACAGCAGCTGGAACAA CTCAACTCCATGGGCTTTATTAACCGTGAGGCCAACCTACAGGCCCTGATCGCCACAGGAGGGGACATCA ATGCCGCTATTGAGAGACTCCTGGGCTCCCAGCTCTCCTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_033526 |
| Insert Size | 1791 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_033526.2, NP_277068.1 |
| RefSeq Size | 3372 bp |
| RefSeq ORF | 1791 bp |
| Locus ID | 94232 |
| UniProt ID | Q99NB8 |
| Gene Summary | Regulator of protein degradation that mediates the proteasomal targeting of misfolded, mislocalized or accumulated proteins (By similarity). Acts by binding polyubiquitin chains of target proteins via its UBA domain and by interacting with subunits of the proteasome via its ubiquitin-like domain (By similarity). Key regulator of DNA repair that represses homologous recombination repair: in response to DNA damage, recruited to sites of DNA damage following phosphorylation by ATM and acts by binding and removing ubiquitinated MRE11 from damaged chromatin, leading to MRE11 degradation by the proteasome (By similarity). MRE11 degradation prevents homologous recombination repair, redirecting double-strand break repair toward non-homologous end joining (NHEJ) (By similarity). Specifically recognizes and binds mislocalized transmembrane-containing proteins and targets them to proteasomal degradation (By similarity). Collaborates with DESI1/POST in the export of ubiquitinated proteins from the nucleus to the cytoplasm (By similarity). Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (PubMed:18079109, PubMed:20940304). Acts as an adapter protein that recruits UBQLN1 to the autophagy machinery (By similarity). Mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (By similarity).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209271 | Ubqln4 (tGFP-tagged) - Mouse ubiquilin 4 (Ubqln4) |
CNY 5040.00 |
|
| MR209271 | Ubqln4 (Myc-DDK-tagged) - Mouse ubiquilin 4 (Ubqln4) |
CNY 4440.00 |
|
| MR209271L3 | Lenti ORF clone of Ubqln4 (Myc-DDK-tagged) - Mouse ubiquilin 4 (Ubqln4) |
CNY 6460.00 |
|
| MR209271L4 | Lenti ORF clone of Ubqln4 (mGFP-tagged) - Mouse ubiquilin 4 (Ubqln4) |
CNY 6460.00 |
