Jmjd7 (NM_001114637) Mouse Untagged Clone
CAT＃: MC214968
Jmjd7 (untagged) - Mouse jumonji domain containing 7 (Jmjd7), (10ug)
CNY 3990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | MGC106779 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC214968 representing NM_001114637
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGGAGGCGGCTCTGGAGGCAGTTCGGAGGGCGTTGCAAGAGTTCCCGGCGGCGGCTCGCGACCTCA ATGTACCTCGTGTTGTGCCCTACCTGGATGAGCCCCCAAGCCCACTCTGCTTCTACCGGGATTGGGTGTG CCCCAACAGGCCCTGCATTATCCGAAATGCTCTGCAGCACTGGCCAGCCCTCCAGAAGTGGTCCCTGTCC TACTTAAGAGCCACGGTGGGCTCCACGGAGGTGAGTGTGGCTGTGACTCCAGATGGTTATGCGGACGCGG TGCGAGGGGACCGCTTTGTGATGCCTGCTGAACGCCGCCTGCCCATAAGCCATGTACTGGATGTGTTGGA AGGTCGGGCCCAGCACCCAGGAGTCCTCTATGTGCAGAAACAGTGTTCCAACCTGCCCACTGAGCTGCCC CAGCTTCTGTCTGACATTGAGTCCCATGTGCCCTGGGCCTCTGAGTCACTGGGGAAGATGCCTGATGCCG TGAACTTCTGGCTGGGTGATGCATCTGCAGTGACATCCTTGCACAAGGACCACTATGAGAATCTGTACTG TGTAGTCTCTGGCGAGAAACACTTCTTGTTACATCCACCCAGCGACCGGCCCTTCATCCCTTACAATCTC TACACACCAGCAACCTACCAGCTGACTGAAGAGGGCACTTTTAGGGTGGTGGACGAGGAAGCCATGGAGA AGGTACCCTGGATCCCACTGGACCCCTTGGCTCCAGACCTGACCCAGTACCCCAGTTACAGCCAGGCACA GGCCCTTCACTGCACAGTGCGGGCCGGCGAGATGCTGTACCTGCCAGCTCTGTGGTTCCACCATGTCCAG CAGTCCCACGGCTGTATTGCTGTGAATTTCTGGTATGACATGGAGTATGACCTCAAGTACAGTTACTTTC AACTGATGGACACCCTCACCAGGGCCACAGGCCTTGACTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001114637 |
| Insert Size | 951 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001114637.1, NP_001108109.1 |
| RefSeq Size | 1383 bp |
| RefSeq ORF | 951 bp |
| Locus ID | 433466 |
| UniProt ID | P0C872 |
| Gene Summary | Bifunctional enzyme that acts both as an endopeptidase and 2-oxoglutarate-dependent monoxygenase (PubMed:28847961) (By similarity). Endopeptidase that cleaves histones N-terminal tails at the carboxyl side of methylated arginine or lysine residues, to generate 'tailless nucleosomes', which may trigger transcription elongation (PubMed:28847961). Preferentially recognizes and cleaves monomethylated and dimethylated arginine residues of histones H2, H3 and H4. After initial cleavage, continues to digest histones tails via its aminopeptidase activity (PubMed:28847961). Additionally, may play a role in protein biosynthesis by modifying the translation machinery. Acts as Fe(2+) and 2-oxoglutarate-dependent monoxygenase, catalyzing (S)-stereospecific hydroxylation at C-3 of 'Lys-22' of DRG1 and 'Lys-21' of DRG2 translation factors (TRAFAC), promoting their interaction with ribonucleic acids (RNA) (By similarity).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG216128 | Jmjd7 (tGFP-tagged) - Mouse jumonji domain containing 7 (Jmjd7), (10ug) |
CNY 2850.00 |
|
| MR216128 | Jmjd7 (Myc-DDK-tagged) - Mouse jumonji domain containing 7 (Jmjd7) |
CNY 2400.00 |
|
| MR216128L3 | Lenti ORF clone of Jmjd7 (Myc-DDK-tagged) - Mouse jumonji domain containing 7 (Jmjd7) |
CNY 4750.00 |
|
| MR216128L4 | Lenti ORF clone of Jmjd7 (mGFP-tagged) - Mouse jumonji domain containing 7 (Jmjd7) |
CNY 4750.00 |
