Gatsl2 (NM_030719) Mouse Untagged Clone
CAT＃: MC211937
Gatsl2 (untagged) - Mouse GATS protein-like 2 (Gatsl2), (10ug)
CNY 3990.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 7530428J21Rik; AW742413; Gats; Gatsl1 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC211937 representing NM_030719
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGAACTGCACATTCTGGAACACCGGCTGCAAGTTGCCAGCGTCGCCAAGGAGAGTATCCCGCTCTTCA CCTACGGCCTCATCAAACTTGCCTTCCTGTCTTCCAAGACCAGGTGCAAGTTTTTCAGTCTGACCGAGAC CCCTGAGGACTACACCATCATCGTAGATGAGGAGGGTTTCCTTGAGCTACCCTCCTCAGAGCACCTGAGT GTGGCTGATGCCACCTGGCTGGCCCTGAACGTGGTGTCCGGTGGCGGCAGCTTCTCCAGCTCCCAGCCCA TCGGTGTGACAAAGATTGCCAAGTCTGTCATTGCCCCACTCGCCGACCAGAACATCTCCGTGTTTATGCT GTCCACCTATCAAACTGACTTCATCCTGGTGCGGGAGCGGGACCTGCCCTTCGTCACTCACACCTTGTCC TCGGAGTTCACCATCCTACGCGTTGTCAATGGAGAAACGGTGGCGGCTGAGAATCTCAGCTTCACCAATG GCTTTGTGAAGCCCAAGATGGTCCAGAGGCCAGTCATCCACCCACTGTCTAGCCCAAGCAACAGGTTCTG TGTCACCAGCCTGGACCCTGACACACTGCCCGCCGTCGCCACCCTTCTCATGGATGTGATGTTCTACTCC AATGGAGTGAAGGACCCCATGGCTGCCAGTGACGATTGTGGCCACATCCGCTTCTTCTCCTTCTCACTCA TTGAGGGCTACATCTCACTGGTGATGGACGTACAGACCCAGCAGAGGTTCCCGAGTCACTTGCTATTCAC GAGTGCATCTGGAGAGCTCTGGAAGATGGTGCGCATAGGAGGACAACCCTTGGGATTTGATGAATGTGGG ATTGTAGCCCAGATCTCAGAGCCCTTGGCAGCTGCAGACATCCCAGCATATTACATCAGTACTTTCAAGT TCGACCATGCATTGGTTCCAGAAGAGAATATCAGTGGGGTTATCCATGCCCTGAAGGTCAGTCAAGCAGG GAAGCATTAG AGCGGACCGACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCC TGGATTACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-RsrII |
| ACCN | NM_030719 |
| Insert Size | 990 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_030719.3, NP_109644.2 |
| RefSeq Size | 4807 bp |
| RefSeq ORF | 990 bp |
| Locus ID | 80909 |
| UniProt ID | Q8CAB8 |
| Gene Summary | Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG204826 | Gatsl2 (tGFP-tagged) - Mouse opposite strand transcription unit to Stag3 (Gats) |
CNY 2850.00 |
|
| MR204826 | Gatsl2 (Myc-DDK-tagged) - Mouse GATS protein-like 2 (Gatsl2) |
CNY 2400.00 |
|
| MR204826L3 | Lenti ORF clone of Gatsl2 (Myc-DDK-tagged) - Mouse GATS protein-like 2 (Gatsl2) |
CNY 4750.00 |
|
| MR204826L4 | Lenti ORF clone of Gatsl2 (mGFP-tagged) - Mouse GATS protein-like 2 (Gatsl2) |
CNY 4750.00 |
