Rmnd5a (BC050876) Mouse Untagged Clone
CAT＃: MC205949
Rmnd5a (untagged) - Mouse required for meiotic nuclear division 5 homolog A (S, (10ug)
CNY 3656.00
货期*
现货
规格
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Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | MGC59617, MTA.D02.090 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC050876
CCCGGGAGAACCAGGTCATCGGCCGGTTCCCGTGAAAACAAAAACAATCGGCGGCGCCGCCGAGGGGCGG CCGAACGCGGCGAGCCAGGGGGGCCCGGGGCGAGACGCGGCGCCGGGTAGGGCGGGCGAGCGAGCGCGAG CGGCGGGGCCGGGGCGCCATGGGGCGGGAGGGCACAGGCTGCGCGGGGCTCCCCCGGCGCCGCGGCTAGC GCGCCCGTCTTGCCTTCGCCTCCCGCGCCGCCCGCTCGCCGCCTTGGGGGAGGAGGAGCAGGACGCGGCC TCGGTGGGGCCCGGGCCGAACCACTGCGGACCCCCGGGCGCCGGGGAGCCGAGCGCCGCGGTCTCCGGCA TGGATCAGTGCGTGACGGTGGAGCGCGAGCTGGAGAAGGTGCTGCACAAGTTCTCGGGCTACGGGCAGCT GTGCGAGCGGGGCCTGGAGGAGCTCATCGACTACACCGGCGGCCTCAAGCACGAGATCCTGCAGAGCCAC GGTCAAGATGCTGAATTATCAGGGACACTTTCACTTGTTCTGACACAGTGCTGCAAAAGAATAAAGGACA CTGTCCAGAAGTTGGCCTCTGACCACAAAGACATCCATAGCAGTGTTTCTCGAGTTGGAAAAGCCATTGA TAAGAATTTTGATTCTGACATTAGCAGTGTGGGAATAGATGGCTGCTGGCAGGCAGACAGCCAACGGCTT CTCAATGAGGTCATGGTGGAACACTTCTTCCGACAAGGAATGCTGGATGTAGCTGAGGAGCTTTGCCAGG AATCTGGTCTGTCTGTAGACCCAAGTCAGAAAGAACCATTTGTGGAGTTAAATAGAATATTAGAAGCATT AAAAGTCAGAGTTCTAAGGCCTGCTCTCGAGTGGGCAGTATCAAACCGAGAAATGCTCATAGCCCAAAAC AGTTCCTTGGAATTTAAGCTACACCGACTGTATTTTATTAGCTTGTTAATGGGTGGAACTACAAATCAGC GAGAAGCCTTACAATATGCGAAAAATTTCCAGCCATTTGCCCTAAATCATCAAAAAGACATTCAGGTATT GATGGGAAGCCTCGTGTACCTGCGACAAGGGATTGAAAACTCACCATATGTTCACTTACTTGATGCAAAC CAGTGGGCTGACATCTGTGACATCTTTACACGGGATGCTTGTGCCCTCCTGGGGCTCTCCGTGGAGTCTC CTCTCAGTGTCAGTTTCTCAGCAGGTTGTGTGGCGCTGCCTGCGCTAATTAACATCAAAGCTGTGATTGA GCAGAGGCAGTGTACTGGAGTTTGGAACCAGAAAGACGAATTACCTATTGAAGTGGACCTTGGTAAAAAG TGCTGGTATCACTCCATATTTGCCTGTCCCATTCTTCGTCAGCAAACAACAGATAACAATCCACCCATGA AATTGGTTTGTGGTCATATTATATCAAGAGACGCCCTGAATAAAATGTTTAATGGTAGCAAATTAAAATG TCCATATTGCTCAATGGAACAGAGTCCAGGAGATGCCAAACAGATATTTTTCTGAAGAATGAGTTTGTTT GCAATTTGTAAGTGAAACTGAATTATGGGTACATTCAAGACAAGAGTGTTCCATTGACTGCAGCTATCCA AGGACCGCCTGTTCATAAGCTATGCTCCAGAGGCTGCCGATTCACTCGTGTGCACGGAGGGGGTGCTCCA GATGGGAATCACACAGGGCTTTCTTCACTCTTGGTCTTCGTTTCTGATCAAGTAAACACCAGCAGTTGTC ATTCAGTGCAGGTTTTTGTACTTCTATATGGTGATTTTTTTACTTAAAAGCAGAAACAGAAGTTGACCTT CCTGACATGTGTTTAATATTCCTCCTGCTTTTACAGATTCTGACGTTTTCTTGATAATTGTAAGCTTGAG AGTGTTTGTGGAAGAACTTACTTTCTTCTTATGTATACATAATTAAATGAAAAGTCTTCATAGGAGTTTG ACAAAATGAATTGTGGTTATAAAACGAATTTGCTTTTTTGTTGTTTTGTTTTTCTTTTTTGGCCTAAGGA AGAAAGCTGTGATAAATTTCAAATTTGCATAGCTTTTCAATGTTTTGCTCTGCTCCCGCTCTTGCTTCAG AGTCGGCACACTCACCTGCATTTGAGTTCTGTCTATAGCCCAGCAGGCTGCCTGTTTAAAATCCCATCAT GAATTTAACAGGCTGATGTGAGAATGAAATAGATATTACTGGGGTTTTGTTGTTGTTTGTTTATTTGTTT TGCTTTTATTACCAAGAGGTGCTTTTTAATAAATGGATATTGAAGTTAGGGTGTTACTAATTTGATGTAT GGTTTCACAGTCTAGCATACTGTCCTTTGACATCTGCCTTTAAGACTTGGCTGAGTGTCTCATTAGTTTA TCATCACAGATACGCAGTGTTATGCATGTGTATAGAAGTGTGTGCACCAGCATCAAACATTGTGTGTGTG GAAGGGAAGAAGCCTGTCCATTCTAAACGCAGTTGCCAGTCTCATCACTTCAGGTCCTTACGGGCAGGCT CTAGCAACTTTCCGTGTATGGACCTCGTTTTTTGCTGTTTTGTGTTTAATTAGTATATTGTTCATGCCTC TCTTCTGCAGTGTCTCATCTCATAGACTGTGAACCTGTATATTATTCAAATGGCTACAGATAATGCTCTT TTCTTTTGTGAGGTCTCTTCATTTAATGCACTGCCCAGAAAGAGCCATGTGTAAGAGTTGTTCTCTGTTT GAGGAACTAACTACATGGAAAAGACTTCTGACTTAAACCCATGAAATACTTCATCTTGAGAAGAGTGCTA TGTGGAAATCACCAAATATCTCGCAACTTTATTTCATCTGGTGTAAATCTGAACATCAACATAGGAAAAC TGTCATGAGAAAATGAAAAAGCATAAACACAGAAGCAACGAGAAATGTGACTCTTGTTATTTTAAACCAC AGACGGACTTGGGTTAAGGGAATGGGGACGACAGCTTTGGTGCTAAGTTAATCAGAAATTGCGAGCATGC ACAGTGGTATGCCAGCCTGGGTGATGCTTTCCTAGGAGAGCCGGTATTTGCTTGTAAGGGAAAGAATGGT ATTGTAGAAAAACCCAAGAAATGACCACGTGGTCAGTTTCATGGTGATGGCTACTGTGTACTGTGTAGGT TACCTGGGTCAAGACTGGTCCAGCTTAGAGTGCATGCTCTGTTCATACTCAGCCTAGCTCACAGTGACTT GTGCTTCACTGTCAGGATGCTCTGTAAAGTTCCTCATCCCTGTGAAGCAGGGAAAGAACAGAGGTGCCTC TGGACTGCAGGAGAAAGGCGTCGTGCCAGGCAGTATCCTGTGGAGGGAGGAGGGTGTACGTTCGTTTACT ATGGATAGTTTTTCCTTTGAATTAAATTGTAGCGTGTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA A |
| Restriction Sites | RsrII-NotI |
| ACCN | BC050876 |
| Insert Size | 1176 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC050876, AAH50876 |
| RefSeq Size | 3431 bp |
| RefSeq ORF | 1176 bp |
| Locus ID | 68477 |
| Gene Summary | Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex. Catalytic activity of the complex is required for normal cell proliferation. The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1.[UniProtKB/Swiss-Prot Function] |
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