Nfkbiz (NM_030612) Mouse Untagged Clone
CAT＃: MC204606
Nfkbiz (untagged) - Mouse nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 1, (10ug)
CNY 5344.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA408868; INAP; Mail |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC058188
GGCCGCAGCCAACCGCGTAGCCATCCGGTGGCGCAGGTGTCTGGGGACCCCGAGCGCCTAGCCTGGGAGC ATGATCGTGGACAAGCTGCTGGACGACAGCCGCGGCGGAGAGGGGCTGCTGGACGCGGCCGGCGACTGCG GCCTCATGACCAGCCCGCTCAACCTGGCTTACTTCTACGGCGCCTCGCCTCCTTCCGCCCCCGGCGCCGG CGACACCGGCTACCTGTCCGCCGTGCCCTCCGCGCCCGGCTCGCCCGGCTCCGACTCCTCCGATTTCTCC TCCACTTCCTCCGTGTCCTCCTGCGGGGCCGTGGAGTCCCGTCCCAGAGGTGGCGCCCGCGCCGAGCGCC CTCAAGTTGAGCCCCACATGGGGGTTGGCAGGCAGCAGAGAGGCCCCTTTCAAGGTGTTCGCGTGAAGAA CTCGGTGAAGGAGCTCCTGCTACACATCCGAAGCAACAAGCAGAAGGCTTCCGGCCAGCCCGTGGATGAG TTTAAGACACAGAGTGTGAACATTGAGCAGCTGACAGACCTGAAGAGTGCAGTGTCCGCAGTGGGGAAAA GAAAGGGACCCGATCCTCTGTCCGATGGACCGGTTTGCAAGAGGCCAGCTCTGTTGCCTTCTCACTTCGT GACATCACCGCAAACGCCTACACCTGGGGAGAGCATGGAAGATGTTCGCCACAGCGAATCCAAGCTGGAT AGCAGCGCTGCCCTGCTTCAGAATATTATAAACATCAAGAATGAGTGCAACCCAGTTTCACTAAACACTG TTCAGGTTAGCTGGATGAGCCCCACGGTTCCCCAGAACTCGCCAAGAGACCAGTGCCAGGATTTCCATGG AGGCCAGGCCTTCTCTCCACCTCAGAAATACCAACCGTTCCAAGTCAGTGGCTCTCCACAGATGATGGAC CAGGCGTCAATGTACCAGTATTCGCCACAAACACAGAACATGCAGCAGCCGCCGCCGCTGCCACCACAGC AGCAACATCAACAGAATTATCCCCACAACTCACCCCTGCAGTTCAGTCCTTACTCCAGAATGTCCCAGTC TCCCAAGTATGATTCCAACCTCTTTGATACTCACGAGCCACAGTTCTGCACGGGCCAAAGTTTTGTGTCT TTACTGACTGGCCCGGGGGAACCCGAGTCTCTTGCTGTTCCCGTTCCGGCTCCCACCAGCATTCCACCCC AAACTGAGACTCAGCTGCAGACCTTCAGCCTGATGCCAAGCAATGCCTGCGAGGCCGTCGTCGGGGTGCA CGATGTGGGCTCGCACTCTTTGGGCACGTCCCTGTCACTCCAGAACATCATGGGAAGCCCGATGAATACC ACCCAGCTGGGGAAGTCATTTTTTCAGTGGCAGGTAGAGCAGGAAGAAAGCAAATTGGCAAATATTCCCC AGGACCAGTTCCTCGCTAGGGACGGAGATGGTGACACGTTTCTCCATATTGCTGTTGCCCAAGGGAGGCG AGCGCTCTCGTATGTCCTTGCAAGAAAGATGAACGCTCTTCACATGCTGGACATTAAGGAGCACAATGGA CAGAGTGCCTTTCAGGTGGCGGTAGCTGCCAATCAGCACCTCATTGTGCAAGATCTGGTAAACCTTGGTG CCCAGGTGAACACCACGGATTGCTGGGGAAGGACACCTCTGCATGTCTGTGCGGAGAAGGGCCACTCCCA GGTGCTCCAGGCCATCCAGAAGGGAGCTGTGAGGAGCAATCAGTTTGTGGATCTTGAGGCAACGAACTAT GATGGCCTGACTCCCCTACATTGCGCGGTCGTGGCTCACAATGCGGTGGTGCACGAACTGCAGAGGAATC GGCAGTCTCATTCGCCCGAAGTGCAGGACCTCTTACTAAGGAATAAGAGCCTGGTAGACACCATTAAGTG TCTGATTCAGATGGGAGCCGCAGTGGAGGCAAAGGATCGTAAGAGTGGCCGCACAGCCCTGCACTTGGCA GCGGAAGAAGCAAATCTGGAACTCATTCGCCTCTTTTTGGAGTTGCCCAGTTGCCTGTCTTTCGTGAATG CCAAGGCTTACAATGGAAACACCGCCCTCCATGTTGCTGCCAGCCTGCAGTATCGGGTGACACAGTTGGA CGCAGTCCGCCTGTTGATGAGGAAGGGAGCTGACCCCAGTACTCGGAACTTGGAGAATGAACAGCCCGTG CATTTGGTCCCCGATGGCCCAGTGGGAGAACAGATCCGACGTATCCTGAAGGGGAAGTCCATTCAGCAGC GAGCACCACCATACTAGGTCCACTGGCGTGGAGCCTGGTTCAGCGACACTCACTGTCAGTTAGGCAGTCC TGATGTATCTGTACATAGACCATTTGCCCTGTATTGGCAAATGTAAGTTGTTTCTATGAAACAAACCCAT TTAGTTCACTATTATATAGTGGATTATATTAAAAGAAAAGAAGACAGATATCTAATTTTCTTGGCAGATT TGCGTATTTCATACCCAGGTATCTGGGATCTATATATCTGAATTTGATCTTGAATGGTAAAATTACCTTC GATAACCAGTAGCTTTCAGGTAGGGAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_030612 |
| Insert Size | 2187 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC058188, AAH58188 |
| RefSeq Size | 2560 bp |
| RefSeq ORF | 2187 bp |
| Locus ID | 80859 |
| UniProt ID | Q9EST8 |
| Gene Summary | Involved in regulation of NF-kappa-B transcription factor complexes. Inhibits NF-kappa-B activity without affecting its nuclear translocation upon stimulation. Inhibits DNA-binding of RELA and NFKB1/p50, and of the NF-kappa-B p65-p50 heterodimer and the NF-kappa-B p50-p50 homodimer. Seems also to activate NF-kappa-B-mediated transcription. In vitro, upon association with NFKB1/p50 has transcriptional activation activity and, together with NFKB1/p50 and RELA, is recruited to LCN2 promoters. Promotes transcription of LCN2 and DEFB4. Is recruited to IL-6 promoters and activates IL-6 but decreases TNF-alpha production in response to LPS. Seems to be involved in the induction of inflammatory genes activated through TLR/IL-1 receptor signaling. May promote apoptosis (By similarity). Involved in the induction of T helper 17 cells (Th17) differentiation upon recognition of antigen by T cell antigen receptor (TCR) (PubMed:25282160).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 both encode the same isoform (a). |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210323 | Nfkbiz (tGFP-tagged) - Mouse nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz) |
CNY 7980.00 |
|
| MG222336 | Nfkbiz (tGFP-tagged) - Mouse nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor zeta (Nfkbiz) transcript variant 1, (10ug) |
CNY 6936.00 |
|
| MR222336 | Nfkbiz (Myc-DDK-tagged) - Mouse nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 1 |
CNY 5336.00 |
|
| MR222336L3 | Lenti ORF clone of Nfkbiz (Myc-DDK-tagged) - Mouse nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 1 |
CNY 9120.00 |
|
| MR222336L4 | Lenti ORF clone of Nfkbiz (mGFP-tagged) - Mouse nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta (Nfkbiz), transcript variant 1 |
CNY 9120.00 |
