Syvn1 (NM_028769) Mouse Untagged Clone
CAT＃: MC204599
Syvn1 (untagged) - Mouse synovial apoptosis inhibitor 1, synoviolin (Syvn1), transcript variant 1, (10ug)
CNY 4568.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1200010C09Rik; AW211966; C85322; D530017H19Rik; Hrd1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC057917
GTCGTAGCTATCCCTGGAATGAGGCGCTTACACATTTTATTTCTTTCATGCCTGACATAAAGTCTGGCCC TTGCTCGCTCCTGCCCCCCGTCCAAATGGCTCGGCCCGCGGAACGCCCCATCTTCCAGGCACATTGAGAG CCGGAGTCTTGGAGGAGTTTAGGGTGGTGATTCTACAACGGCGACTAGCAAGTGGCGGGCTTCAGCCCTT TCCCGCTGCTCTCCTGGTCGCGACCACACGTCACAGCTCTCGCTCGTTCCGGTTGCTCGCGCACGGGCCC CAGAAGCGCAGGCGAGATCGGAGCGCGCAAAGAGAACTTGGTACGGTCCACTCCGCCGCGCCCCGCGCCG CCGGAAGTGAGGTGTCTTACCCCCGAAGTTCCGGTTCGCAGGGGGTGGGGAGTGTTGTTAACCGGAGCGG CTGCCGCAGTCGCGGTGATTGAGCGTGCTCGCGGCGCTGGGCTCCTGGTCTCTGGGCCAGGGCGATGTTC CGCACCGCAGTGATGATGGCGGCCAGCCTGGCGCTAACCGGGGCAGTGGTGGCTCATGCCTACTACCTCA AACACCAGTTCTACCCCACTGTAGTGTATTTGACCAAGTCCAGCCCCAGCATGGCAGTCCTGTACATCCA GGCCTTTGTCCTTGTCTTCCTCTTGGGCAAGGTGATGGGCAAGGTGTTCTTCGGGCAGCTGAGGGCAGCA GAGATGGAGCACCTTCTGGAACGGTCCTGGTACGCTGTTACTGAGACTTGTTTGGCCTTCACCGTTTTTC GGGATGACTTCAGCCCTCGCTTTGTGGCGCTCTTTACGCTGCTCCTCTTCCTCAAATGTTTCCATTGGTT GGCTGAAGACCGTGTGGACTTTATGGAACGCAGCCCCAACATCTCCTGGCTCTTCCACTGCCGCATCGTC TCTCTCATGTTTCTCCTGGGTATCCTGGACTTCCTCTTCGTCAGCCACGCTTATCACAGCATCCTGACCC GTGGGGCTTCTGTGCAGCTGGTATTTGGCTTTGAGTACGCCATTCTGATGACCATGGTGCTTACCATCTT CATCAAGTATGTGCTGCACTCCGTGGACCTCCAGAGCGAGAACCCCTGGGACAACAAGGCTGTATACATG CTCTACACGGAGCTGTTTACAGGCTTCATCAAGGTCCTGCTGTACATGGCCTTCATGACCATCATGATCA AGGTGCACACATTCCCACTCTTTGCCATTAGGCCCATGTACCTGGCCATGAGGCAGTTCAAGAAAGCTGT GACAGATGCCATCATGTCTCGCCGAGCCATCCGCAACATGAACACACTGTACCCAGATGCCACCCCCGAG GAGCTCCAGGCAGTGGATAATGTCTGTATCATCTGCAGAGAAGAAATGGTGACTGGTGCTAAGAGATTGC CTTGCAACCACATCTTTCACACGAGCTGCCTGCGCTCCTGGTTCCAGAGACAGCAGACCTGCCCGACATG CCGCATGGATGTCCTGCGGGCATCGTTGCCAGCCCAGTCACCACCACCTCCTGAGCCTGCTGACCAAGGA CCACCCCCCGCCCCTCATCCCCAACCGCTGCTGCCACAGCCCCCTAATTTCCCCCAGGGCCTCCTGCCTC CTTTTCCTCCAGGCATGTTCCCACTGTGGCCCCCAATGGGTCCCTTTCCACCTGTCCCGCCTCCCCCAAG CTCAGGAGAGGCTGCGGCCCCTCCACCCACCAGTACAGCCGTTTCTCGGCCTAGTGGAGCAGCCACCACC ACAGCTGCTGGCACCAGTACTTCTGCCCCAGCACCTGGGTCTGTACCTGGCCCAGAGGCTGGTCCTGCCC CCGGCTTCCCTTTCCCTCCTCCTTGGATGGGTATGCCTCTGCCTCCACCTTTTGCCTTCCCCCCAATGCC TGTGCCCCCTGCGGGCTTTGCTGGCCTAACCCCAGAGGAGCTGCGAGCACTAGAGGGCCATGAGCGGCAG CACCTGGAGGCCCGGCTGCAGAGTCTGCGCAACATACACACACTACTGGATGCTGCCATGCTTCAAATCA ACCAGTACCTCACTGTGCTGGCTTCCCTGGGGCCCCCCAGGCCAGCTACTTCAGTGAACCCCACTGAAGA GACTGCCTCTACAGTGGTATCTGCTGCCCCTTCCACCAGCGCCCCCAGCTCTGAGGCTCCTACCCCGTCT CCGGGAGCTTCCCCACCAATTCCTGAAGCAGAAAAGCCTCCTGCTCCTGAGTCAGTGGGCATTGTAGAGG AGCTTCCCGAGGACGGAGAGCCTGATGCTGCAGAACTCCGCCGGCGTCGCCTGCAGAAGCTGGAGTCCCC TGTTGCCCACTGACACTGCCCAGACCTGGCCCTGTTCTCTTGAGTGGCCCTCACTGGAACACGTCCTGCC ATCAAGTGCCAGCTCCCTCTCTGCTTGCACCAGGGAGTAATAGCCCCAGTTGAGAAAGACTTGGCAGGAT CTCTGAGGATCAAGGAGAAGTGTCTGGGCTTCCAGTTGATCCATCCCCAGTGCCCCTGGCAGCCATGGAG ATACTGGTCAGCTCTAACCTCCCTCCACTTCTGCCATGTTCAACTGGGGCCTTCAAAGTAGAAGCTGAAT CTCTGGTAAGCCTTCTCTTCCATGCTTTCTGGGAGAAGGTGAAGCCCCTCCAAGCCCTGCTTGTGAGTAT GGGACCATGCTGCAGTGCCGAACAGTATTAGCTTCTGTTCCCAAGTGTGGAAACCCAGAGGGGCTGAAGA CAGACCAGGACCTTGCCCCACCCTCCTGCCAAGACTGGTACCAGTCTCTTTCCTCTAGCCCAGTCTTCCC AGAACCCCTTTGTGATGGTGGCTGTGCCCCCCGAAGCCCTGTGGCATTTCCATGTCTTACTGGCAACCAC ACAACTCAGGGAAAGGAGTGCCTGGGGGTGGGGCACAGGCGGGCAGCACTGAGGGACCCTGCCCTGCCCC TCCCCAGCTCTTTCCCCATCTCACCCAGCAGCCACTGCCTGGTGGGCCTGGCTAAGGGTGTGTGCTGCTC CTTAAACCACTGCTCCCCAGAACCCAAGGCAGGCCACCTCCAACCTGTGGGATGTCGTCAGGATTGGAAC TATTCTGTACCTACTGGCTTTGGGCTTAAATTTTGTCTTCTGAATTTGAATGCTTGACCCCAGGAAGGAG GAGCAGGTGTGGGGCTAGGTACCTGGACTTCGCAGTTTAGAACAAGCTCTGGGCCGGGCCGGGCCAGGCC AGGCCTAGGGAGCCAAGGCCTAGCTGCTGCTTCCTTCTTTTGGTTTTGTGTTACAGGAGTTTCTGGAGAG TTTCAGATGATTATTTAATTTGTAAATATTGTATAAATTTTAATAGCTTAAATTGTATATACAGCTCAAT AAAAACTTGCATTAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_028769 |
| Insert Size | 1839 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC057917, AAH57917 |
| RefSeq Size | 3388 bp |
| RefSeq ORF | 1839 bp |
| Locus ID | 74126 |
| UniProt ID | Q9DBY1 |
| Gene Summary | Acts as an E3 ubiquitin-protein ligase which accepts ubiquitin specifically from endoplasmic reticulum-associated UBC7 E2 ligase and transfers it to substrates, promoting their degradation (PubMed:12975321, PubMed:15611074). Component of the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins (PubMed:12975321, PubMed:15611074). Also promotes the degradation of normal but naturally short-lived proteins such as SGK. Protects cells from ER stress-induced apoptosis. Sequesters p53/TP53 in the cytoplasm and promotes its degradation, thereby negatively regulating its biological function in transcription, cell cycle regulation and apoptosis (PubMed:17170702). Required for embryogenesis (PubMed:15611074). Mediates the ubiquitination and subsequent degradation of cytoplasmic NFE2L1 (PubMed:21911472).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG209408 | Syvn1 (tGFP-tagged) - Mouse synovial apoptosis inhibitor 1, synoviolin (Syvn1) |
CNY 6650.00 |
|
| MR209408 | Syvn1 (Myc-DDK-tagged) - Mouse synovial apoptosis inhibitor 1, synoviolin (Syvn1), transcript variant 1 |
CNY 6080.00 |
|
| MR209408L3 | Lenti ORF clone of Syvn1 (Myc-DDK-tagged) - Mouse synovial apoptosis inhibitor 1, synoviolin (Syvn1), transcript variant 1 |
CNY 7980.00 |
|
| MR209408L4 | Lenti ORF clone of Syvn1 (mGFP-tagged) - Mouse synovial apoptosis inhibitor 1, synoviolin (Syvn1), transcript variant 1 |
CNY 7980.00 |
