Ncstn (NM_021607) Mouse Untagged Clone
CAT＃: MC203928
Ncstn (untagged) - Mouse nicastrin (Ncstn), (10ug)
CNY 5192.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 9430068N19Rik; AA727311; Aph2; D1Dau13e; Kiaa0253; mKIAA0253; Nct |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC019998
CGGAGAGGCAAGATGGCTACGACTAGGGGCGGCTCTGGGCCTGACCCAGGAAGTCGGGGTCTTCTTCTTC TGTCTTTTTCCGTGGTACTGGCAGGATTGTGTGGGGGAAACTCAGTGGAGAGGAAAATCTACATTCCCTT AAATAAAACAGCTCCTTGTGTCCGCCTGCTCAACGCCACTCATCAGATTGGCTGCCAGTCTTCAATTAGT GGGGATACAGGGGTTATCCACGTAGTGGAGAAAGAAGAAGACCTGAAGTGGGTGTTGACCGATGGCCCCA ACCCCCCTTACATGGTTCTGCTGGAGGGCAAGCTCTTCACCAGAGATGTAATGGAGAAGCTGAAGGGAAC AACCAGTAGAATCGCTGGTCTTGCCGTGACTCTAGCCAAGCCCAACTCAACTTCAAGCTTCTCTCCTAGT GTGCAGTGCCCAAATGATGGGTTTGGTATTTACTCCAACTCCTACGGGCCAGAGTTTGCTCACTGCAAGA AAACACTGTGGAATGAACTGGGCAACGGCTTGGCTTATGAAGACTTTAGTTTCCCCATCTTTCTTCTTGA AGATGAGAACGAAACCAAGGTCATCAAGCAGTGCTATCAAGATCACAACCTGGGTCAGAATGGCTCTGCA CCAAGCTTCCCATTGTGTGCTATGCAGCTCTTCTCACACATGCACGCCGTCATCAGCACTGCCACCTGCA TGCGGCGCAGCTTCATCCAGAGCACCTTCAGCATCAACCCAGAAATCGTCTGTGACCCCTTATCTGACTA CAACGTATGGAGCATGCTTAAGCCTATAAATACATCTGTGGGACTAGAACCTGACGTCAGGGTTGTGGTT GCGGCCACACGGCTGGATAGCCGGTCCTTTTTCTGGAATGTGGCCCCAGGGGCTGAAAGTGCTGTAGCCT CCTTTGTCACTCAGCTGGCTGCAGCTGAAGCTTTGCACAAGGCACCTGATGTGACCACTCTATCCCGAAA TGTGATGTTTGTCTTCTTCCAGGGGGAAACTTTTGACTACATTGGCAGCTCACGGATGGTCTATGATATG GAGAACGGCAAGTTTCCCGTGCGGCTCGAGAACATCGACTCCTTCGTGGAGCTGGGACAGGTGGCCCTAA GAACTTCACTAGATCTCTGGATGCACACAGATCCCATGTCTCAGAAAAATGAGTCTGTGAAAAACCAGGT GGAGGATCTTCTGGCCACTCTGGAGAAGAGCGGTGCTGGTGTCCCTGAAGTTGTCCTGAGGAGACTGGCC CAGTCCCAGGCCCTTCCACCTTCATCTCTACAACGATTTCTTCGGGCTCGAAACATCTCTGGCGTGGTCC TGGCTGACCACTCTGGCTCCTTCCACAATCGGTATTACCAGAGCATTTATGACACGGCTGAGAACATTAA TGTGACCTATCCTGAGTGGCAGAGCCCAGAAGAGGACCTCAACTTTGTGACAGACACTGCCAAGGCACTG GCGAATGTGGCCACAGTGCTGGCGCGTGCACTGTATGAGCTTGCAGGAGGAACCAACTTCAGCAGCTCCA TCCAGGCTGATCCCCAGACAGTTACACGTCTGCTCTATGGGTTCCTGGTTAAAGCTAACAACTCATGGTT TCAGTCGATCCTGAAACATGACCTAAGGTCCTATTTGGATGACAGGCCTCTTCAACACTACATCGCCGTC TCCAGCCCTACCAACACGACTTACGTTGTGCAGTACGCCTTGGCAAACCTGACTGGCAAGGCGACCAACC TCACCCGAGAGCAGTGCCAGGATCCAAGTAAAGTCCCAAATGAGAGCAAGGATTTATATGAATACTCGTG GGTACAAGGCCCTTGGAATTCCAACAGGACAGAGAGGCTCCCACAGTGTGTGCGCTCCACAGTGCGACTG GCCAGGGCCTTGTCCCCTGCCTTTGAACTGAGTCAGTGGAGCTCCACAGAATACTCTACGTGGGCGGAGA GCCGCTGGAAAGACATCCAAGCTCGGATATTCCTAATTGCCAGCAAAGAGCTTGAGTTCATCACGCTGAT CGTGGGCTTCAGCATCCTTATCTTCTCTCTCATCGTCACCTACTGCATCAATGCCAAAGCCGACGTCCTT TTTGTTGCTCCCCGAGAGCCAGGAGCTGTGTCTTACTGAAGAGGACTCTAGCTCTGCCTGCCTGCTCTGA ACTTTACTTCCCAGACCAGGTGTCCGGCTGGGAACAAACCACTAATTTGTCACTGGACTGTCTCTGGGCC TGCTTAGACGGGGATTGACACACAGAATGGAACTGTGAGTGGAGAGATGAATAAGTTGCCCCCCCAGCCC CCCTTTCCCATTTGTTTCTCCTTCTCTAATCCCAGGGACTATGGTAGAGACTTGCTGCTCCTAACTCCCC AGTTACCCACCCTCCTCTGCCCTTTCTCGGGATACCTTCTGTCCTTCCATCCTGCCCTGTACTGCCCTCT GACTCCACTGTCACCCGACACCCCTCCCCCATATTCAGCCACCTGCTGCACCAGGAAGAGGGTGTGAAAG ATTGTGCATCTGCATTCAACTACCCTGAACCCTTAGGGAAGAAATGGATTCCCTGGCTGAGCCAGTGTCT CTTTCCCACTGTCCTTTCTCCAGGTGTGCAGATGGCATGTTAGTGTGGGCACGCTGTTAAGTGGGTATCC CACCTCCAGCCCACAGTGCTCAGTTGTACTTTTTATTATTAAACTATAATTATCTAAAAAAAAAAAAAAA A |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_021607 |
| Insert Size | 2127 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC019998, AAH19998 |
| RefSeq Size | 2731 bp |
| RefSeq ORF | 2127 bp |
| Locus ID | 59287 |
| UniProt ID | P57716 |
| Gene Summary | Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG210183 | Ncstn (tGFP-tagged) - Mouse nicastrin (Ncstn) |
CNY 6370.00 |
|
| MR210183 | Ncstn (Myc-DDK-tagged) - Mouse nicastrin (Ncstn) |
CNY 5192.00 |
|
| MR210183L3 | Lenti ORF clone of Ncstn (Myc-DDK-tagged) - Mouse nicastrin (Ncstn) |
CNY 7700.00 |
|
| MR210183L4 | Lenti ORF clone of Ncstn (mGFP-tagged) - Mouse nicastrin (Ncstn) |
CNY 7700.00 |
