Scaf4 (NM_178923) Mouse Untagged Clone
CAT＃: MC203554
Scaf4 (untagged) - Mouse SR-related CTD-associated factor 4 (Scaf4), (10ug)
CNY 8424.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | AA517739; Sfrs15; Sra4; Srsf15 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC057592
GAGAGACAGAGAGGCCCGCCCGCTCGCCGGCCGGGCCAGTGTGGGCCAGTGCGTGAGGGAGGGCGCGGGG GGCCGTGTCAGCGCGACGCAGAGCGCAGCCGCCGCCGCCAAACGGACATGTTGGAGCCCCGCGCTGCCGC CGCCTCCCATCCCTCCTCCGGCGCACGGGACTGAGCAGGGGCCCGCCGCCTCTGCCTGCGCTCGACCGGC CCAGCCTCGCCGCCTCGGCCGCAGCCCCTTCCTGCTCGGCCTCCGCCGCTCGTCGCCTCCCGTCCTCCTC CCCCTCCACGCCCAAGGGCCCTGCCGGCACCCGGCCCTACTCAGCCGCCGCTCCAGGTCTAGGTGACCGG CGGGCCCGGAGCAGCCGCAGCCGCCGCCGCAACGCGCGCGAACATGGACGCCGTCAACGCCTTCAACCAG GAGCTCTTCTCACTTATGGATATGAAGCCTCCCATCTCTAGAGCCAAGATGATTCTCATTACTAAAGCTG CTATCAAAGCTATTAAGCTTTATAAGCACGTTGTTCAAATAGTAGAAAAGTTCATCAAAAAGTGTAAGCC AGAATATAAGGTTCCAGGCCTGTATGTCATCGACTCCATCGTGAGACAGTCTCGGCACCAGTTTGGAACT GATAAAGATGTTTTTGGGCCAAGATTCTCTAAAAATATAACTGCTACATTCCAGTATTTATATCTTTGTC CATCTGAAGATAAGAGTAAAATAGTTCGTGTCCTAAATCTTTGGCAAAAAAATGGAGTGTTCAAAATTGA AATTATTCAGCCTCTTTTGGACATGGCAGCAGGAACCAGTAATGCTGCTCCAGTAGCAGAAAATGTCACC AACAATGAAGGCTCACCTCCACCCCCAGTAAAAATCTCTTCTGAACTTGCACAAGCTCCCACAAATTCCA TGCCTACTGTAGCCCAGCTGCCCAGCTCCGATGCCTTTGCTGCTGTGGCTCAGCTGTTCCAGACAACTCA AGGCCAGCAGCTTCAGCAGATCCTTCAGACTTTTCAACAGCCTCCACAACCACAGTCTCCCGCCCTTGAC AGTGCTGTGATGGCTCAGGTTCAGGCTATCACAGCTCAGTTAAAGACAGCTCCTACACAGCCACCCGAGC AAAAAACTGCATTTGACAAGAAGCTGCTTGATAGATTCGATTACGATGACGAGCCAGAAGCTGTGGAAGA CTCAAAGAAAGAGGATGCTGCAGCCATCAGCACCGCAGCCCTTGCCACGGCTGCGCCTCCTGCACCCACT GCAGCCACACCTGCTGTTGCCACGGCTGTGCCTGTGCCCTCTGCTACCTCTCCCCCTCCTCCACAGACCC CATTTGGGTACCCTGGAGATGGCGTGCAGCAGCCAGCATACACACAGCATCAAAGTATGGACCAGTTTCA GCCTCGAATGATGCCAATACAGCAGGATACGATGCACCATCAGGTTCCACTTCCTCCTAATGGACAGATG CCAGGATTTGGGCTTCTTTCTGCACCACCTCCATTTCCTCCCATGCCTCAGCCGGGGATGCCGCAGCCTG GGATGGCTCAGCCGGGATTGGCACAGCCGGGGATGGCTCAGCCTACAATGCCACAGCCAGGGATGCCTCA GCCAGGGATGCCTCAGCCTGGGATGGCTCAGCCGGGATTGGCACAGCCGGGGATGGCTCAGCCTGGGATG CCTCAGCCTGCCATGCCTCAGCCTGCCATGCCTCAGCCGGGGATGGCTCAGCCTGGGGTTTCTCCAGCTC CACCAGTACAGCCAACTTTCCAATCAACTTTTCAGCCACAAAATGAACCCCATTCACAAAAACCACATCA GCAGGAAATGGAAGTAGAGCAGCCTTGTGTTACAGAGGTTAAGCGGCATGTGCCCGAGAGCAGAAAGTCG AGATCCAGGTCAGCATCCAGGTCACCAAAAAGGAGAAGATCTAGGTCTGGCTCTAGGTCTCGGAGATCCC GCCACCGTCGCTCTCGGTCTCGGTCCAGGGACAGGCGCCGACACTCACCTCGCTCTCGATCTCAAGAAAG ACGGGATCGAGAAAAAGAGAGGGAACGGCGGCAGAAAGGCCTCCCTCAGATCAAGTCAGAAACTGCAAGT GTTTGTAGTACCACACTGTGGGTGGGACAACTGGACAAAAGGACTACTCAGCAGGATGTTGCCAGTCTCT TAGAAGAGTTTGGTCCAATTGAATCGATTAATATGATTCCTCCCAGGGGCTGTGCCTACATCGTCATGGT TCATAGACAAGATGCATACCGTGCCCTGCAGAAACTGAGCCGAGGAAACTACAAGGTGAACCAGAAATCC ATAAAGATTGCCTGGGCCTTGAACAAAGGAATAAAGGCGGATTATAAACAGTATTGGGATGTTGAACTTG GTGTCACTTACATTCCGTGGGACAAAGTCAAAGCTGAGGAGCTGGAGAGTTTCTGTGAAGGAGGCATGCT GGACAGTGACACACTTAACCCAGATTGGAAAGGCATCCCCAAGAAGCCTGACAATGAAGTTGCCCAGAAT GGAGGTGCAGAAACCTCCCACACAGAGCCAGTTTCCCCCATACCTAAGCCTGTGCCTGTGCCGGTCCCTC CCATCCCTGTTCCTGCGCCTATAACAGTGCCACCTCCACAGGTCCCGCCCCATCAGCCGGGCCCTCCTGT TGTCGGTGCTCTCCAGCCGCCCGCTTTCACCCCTCCCTTAGGAATGCCCCCTCCAGGCTTTGGCCCTGGC GTTCCTCCTCCCCCTCCTCCTCCACCATTTTTGCGCCCAGGATTCAACCCAATGCATTTACCACCAGGTT TCCTTCCTCCTGGACCCCCACCTCCTATAACTCCACCAGTATCCATTCCTCCACCTCACACTCCACCAAT AAGCATCCCAAACTCTACTATCGCTGGTATAAATGAAGACACTACAAAAGACTTATCTATTGGAAATCCC ATTCCAACAGTGGTGTCTGGGGCTAGAGGAAATGCCGAGTCTGGTGACAGTGCGAAAATGTATGGTTCTG CTGGGCCACCTGCTGCACCCACGAGTCTGCCCACCCCTCCTGTAACCCAGCCTGTGTCACTGCTTGGCAC TCAAGGAGTTGCACCGGGTCCTGTAATTGGGCTCCAGGCACCCTCTACCGGTCTTCTTGGTGCCAGACCT GGCCTGATCCCACTCCAGCGCCCCCCAGGGATGCCTCCACCACATTTGCAACGGTTCCCTATGATGCCAC CTCGGCCCATGCCACCTCACATGATGCACAGGGGGCCACCACCAGGACCAGGGGGCTTTGCCATGCCCCC ACCTCATGGAATGAAAGGGCCCTTCCCACCACATGGCCCCTTTGTTAGGCCTGGTGGGATGCCAGGGCTG GGGGGCCCAGGGCCAGGCCCGGGAGCATCAGAAGACAGAGATGGAAGGCAGCAACAACCACAGCAGCAGC CACCGCCACAGCAGCAGCAGCAGCAGCAGCAGCCGCAGCAGCAGCCACCACAGCAGTCACCATCACAGCA GCCAGCGCCAGCTCAGCAGCAGCCACCGCAGTTTAGAAATGATAGCAGGCAGCAGTTCAACTCAGGTAGA GACCAAGAAAGGTTTGGAAGAAGATCTTTTGGAAGTAGGGTGGAAAATGACCGGGAACGGTATGGGAGCC GTAATGACGATAGAGATAATAGTAACCGTGAAAGGAGAGAGTGGGGAAGAAGGAGCCCTGACCGGGACAG GCACAGAGACTTGGAAGAGAGAAGTAGACGCTCTAGTGGGCATCGGGACAGAGACAGGGATTCTAGAGAT AGAGAGTCCCGTAGAGAGAAGGAAGAAAATCGAAAGGAGAAGCACGAGGTGGCAGACAGGGCAGGTGGTA ACAAAGCTGTGGAACCTCCCCTTAGCCAAGTGGGAACCATAGACACTGTCTCAGAACTTAATAAGGGGGA GGCCATGGCCACGGTGGTAAAGCCTGAAGAGTCGCCTGCTGAGGTTACCTCACCCGTTGGACCCGAGAAG GATCCTGGCTCAGCAGCAGAGCCTCCTCGCTAGAGACTGGATGTGACAGAATGTGACAGTGACACTTGGG TGTAGAACATGAGGTGTACAGATGCTGTATAATATCCGCTCCTGCTACATCATCCCACAGTAGTTGGTGG GGATTGTAAGCAATTTGATTGCTTTCCTTCTATTTAAAAATAGCCAAAAAAAAAAAAAAAAAA |
| Restriction Sites | AscI-NotI |
| ACCN | NM_178923 |
| Insert Size | 3630 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC057592, AAH57592 |
| RefSeq Size | 4193 bp |
| RefSeq ORF | 3630 bp |
| Locus ID | 224432 |
| UniProt ID | Q7TSH6 |
| Gene Summary | Anti-terminator protein required to prevent early mRNA termination during transcription. Together with SCAF8, acts by suppressing the use of early, alternative poly(A) sites, thereby preventing the accumulation of non-functional truncated proteins. Mechanistically, associates with the phosphorylated C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit (POLR2A), and subsequently binds nascent RNA upstream of early polyadenylation sites to prevent premature mRNA transcript cleavage and polyadenylation. Independently of SCAF8, also acts as a suppressor of transcriptional readthrough.[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG211804 | Scaf4 (tGFP-tagged) - Mouse splicing factor, arginine/serine-rich 15 (Sfrs15) |
CNY 10550.00 |
|
| MR211804 | Scaf4 (Myc-DDK-tagged) - Mouse SR-related CTD-associated factor 4 (Scaf4) |
CNY 8424.00 |
|
| MR211804L3 | Lenti ORF clone of Scaf4 (Myc-DDK-tagged) - Mouse SR-related CTD-associated factor 4 (Scaf4) |
CNY 11500.00 |
|
| MR211804L4 | Lenti ORF clone of Scaf4 (mGFP-tagged) - Mouse SR-related CTD-associated factor 4 (Scaf4) |
CNY 11500.00 |
