Tmem106a (NM_144830) Mouse Untagged Clone
CAT＃: MC201980
Tmem106a (untagged) - Mouse transmembrane protein 106A (Tmem106a), (10ug)
CNY 3600.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 0610008L10Rik; AI043106; BC022145 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC022145 sequence for NM_144830
GTCACCTGCAGAATCCCCTAGTAGAGAGGACTTGACCCTCCCGGTAGACAAGAGTCCCTGCTCCCCACTT TCAACACATTGACTCTCTCTGGTCTCCGCTGAATTGAGCTGTTCAACTCCACCCTACCCTAGAGGCCCTT CTCCCCAAAGGAGCATTCCAGAAAACCCAATCTTGGAGCTGAGCAGAGCCTGGAATCCCAGACCTAAACC AGTGAAAAATTCCGCTGGACTATGGGTAAGGCAGTCTCCCAGCTCACCTCTCGGAAGGATGAGGACAAGC CTATCCTACCTGATAACCCAGCCATGGCCAGCCAGGCTGCCAACTACTTCAGCACTGGTAGCAGCAAGCC AGCACACTCCTGTATGCCTTATGAAAAGGCTGCTAGTTCCAGCTTTGTGACTTGTCCTACCTGCCAAGGC AATGGGGAGATCCCCCAAGAGCAAGAGAAGCAGCTGGTTGCTCTCATCCCTTATGGAGACCAAAGGCTGA AGCCCAGACGCACGAAGCTCTTTGTGTTCCTGTCGGTGGCCATCTGCCTGCTGATTTTCTCCCTCACCAT CTTTTTCCTGTATCCCCGGCCCATTGCTGTGCGTCCTGTCGGCCTCAACTCTTCCACAGTAACCTTTGAA GACGCTCACGTACAGCTCAACACGACGAATGTCCTGAACATCTTCAACAGCAACTTCTATCCCATCACAG TGACACAGCTGACGGCCGAGGTGCTCCACCAGGCCTCTGTGGTAGGCCAGGTCACCAGCAGCCTCCGCCT GCACATCGGCCCATTGGCCAGTGAGCAGATGCCTTACGAAGTTGCCAGCAGGATTTTGGATGAAAACACA TACAAAATCTGTACATGGCCGAAAATCAGAGTCCACCATATTCTTTTGAATATCCAGGGTTCTCTGACCT GCTCCTTCCTAAGCCATCCGCAACAGCTGCCCTTCGAGAGCTTTGAATATGTAGACTGCAGAGAAAACAT GTCCCTGCCCCACCTGGAGCTGCCCCGCCCAGCCTGATCTGTCTGCCGCCCCTGGACTCCAGGCACCTGC AAGCTGATCTGCAGCTCAGCTCCGTGGAGCTCAAGGAAAGACTGTAGGGACTTTGTTGAAGGAAAAGTCC TGCTTTGGGCCCTGCCTTCCCCTAACACCCTCAGCACACAGAGCTTCTGTAACAATGTCATAGTCCCTGA GTCCTCAGACCTCCCCACTCCCCCACGAGTCGCTTCTGATGGATCTTACCCATGGTCTGTGTGGGGAGGA ACGGCTACCTTGGCGTTGTCTTGGGACTGAGCATGTTGGTTACCCAGCTCCGCCAGGGTGGGTCTTCAAT CGCAACGAAGAGAAAGCTGTAGTTTTATCTAGACTTTGCAGCATGGATGAATCTTTTTCAAGCTCTCCTC CCAGTAATAAGTGGCTTTGGGGATATCCAGTGCTGTTTCCAAGGTCTCCTTGGGTGACTATAAATGTTCT CCTGTACAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_144830 |
| Insert Size | 786 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC022145, AAH22145 |
| RefSeq Size | 1492 bp |
| RefSeq ORF | 786 bp |
| Locus ID | 217203 |
| UniProt ID | Q8VC04 |
| Gene Summary | Activates macrophages and polarizes them into M1-like macrophages through the activation of the MAPK and NF-kappaB signaling pathway (PubMed:26215746). Upon activation, upregulates the expression of CD80, CD86, CD69 and MHC II on macrophages, and induces the release of pro-inflammatory cytokines such as TNF, IL1B, IL6, CCL2 and nitric oxide (PubMed:26215746). May play a role in inhibition of proliferation and migration (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. Variants 1 through 4 encode the same protein. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG203427 | Tmem106a (tGFP-tagged) - Mouse transmembrane protein 106A (Tmem106a) |
CNY 4370.00 |
|
| MR203427 | Tmem106a (Myc-DDK-tagged) - Mouse transmembrane protein 106A (Tmem106a) |
CNY 3600.00 |
|
| MR203427L3 | Lenti ORF clone of Tmem106a (Myc-DDK-tagged) - Mouse transmembrane protein 106A (Tmem106a) |
CNY 5890.00 |
|
| MR203427L4 | Lenti ORF clone of Tmem106a (mGFP-tagged) - Mouse transmembrane protein 106A (Tmem106a) |
CNY 5890.00 |
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