Agtr1a (NM_177322) Mouse Untagged Clone
CAT＃: MC201798
Agtr1a (untagged) - Mouse angiotensin II receptor, type 1a (Agtr1a), (10ug)
CNY 5488.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 1810074K20Rik; AG2S; Agtr-1a; Agtr1; AI551199; Angtr-1a; AT1; AT1a; AT2R1; AT2R1A |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC036175 sequence for NM_177322
GGACTGGATGATGCTGTCTGGCCGGAGAGGACTCGAGGCTTGAGTCCTGGTCCACGGGTCGCTGGGGTGG GTCGCTGGGGTGGCTGAAGCCAGTACCAGCTCTGCGGCTCTCCCAGCTCTGCTGCTCTCCCGGACTTAAC ATATGAAAGATTGGTATAAAATGGCTGGCATTTTGTCTGGATAACTCACAGCAACCCTCCAAGAAAGCCA TCACCAGATCAAGTGCATTTTGAACAGTGTCTGAGACCAACTCAACCCAGAAAAGCAAAATGGCCCTTAA CTCTTCTACTGAAGATGGCATCAAAAGAATTCAAGATGACTGCCCCAGGGCTGGCAGGCACAGTTACATA TTTGTCATGATCCCTACTCTCTACAGCATCATCTTTGTGGTGGGAATATTTGGAAACAGCTTGGTGGTGA TCGTCATCTACTTTTACATGAAGCTGAAGACTGTGGCCAGTGTCTTTCTTCTAAATCTCGCCCTGGCTGA CTTATGCTTTTTGCTGACTTTGCCCCTGTGGGCTGTCTATACCGCTATGGAATACCGCTGGCCCTTCGGC AATCACCTATGTAAGATCGCTTCGGCCAGCGTCAGTTTCAACCTCTACGCCAGCGTGTTCCTGCTCACGT GTCTCAGCATCGATCGCTACCTGGCCATTGTCCACCCGATGAAGTCTCGCCTCCGCCGCACGATGCTGGT GGCCAAAGTCACCTGCATCATCATCTGGCTGATGGCTGGCTTGGCCAGTTTGCCAGCCGTCATCCACCGA AATGTGTATTTCATTGAGAACACCAATATCACTGTTTGCGCTTTTCATTACGAGTCCCGGAATTCAACGC TCCCCATAGGACTGGGCCTAACCAAGAACATCCTGGGCTTCCTGTTCCCTTTCCTAATCATTCTTACCAG CTATACTCTTATATGGAAAGCTCTAAAGAAGGCTTATGAAATTCAGAAGAACAAGCCAAGAAATGATGAC ATCTTTAGGATAATTATGGCGATTGTGCTTTTCTTCTTCTTCTCCTGGGTCCCCCACCAAATATTCACAT TCCTGGATGTGCTGATTCAGCTGGGCGTCATCCATGACTGTAAAATTGCCGACATCGTGGACACTGCCAT GCCCATAACCATCTGCATAGCGTATTTTAACAACTGCCTGAACCCTCTGTTTTACGGCTTTCTGGGGAAA AAATTTAAAAAGTATTTCCTCCAGCTCCTGAAATATATTCCCCCAAAGGCCAAGTCGCACTCAAGCCTGT CTACGAAAATGAGCACGCTCTCCTACCGCCCCTCAGATAACATGAGCTCAGCCGCCAAAAAGCCTGCGTC TTGTTCTGAGGTGGAGTGACAGGTTCAAAGCTTGCTGGCAATGTAATGCCCTGACAGAAACCAGGGCAGC ATCGGACTAAATGGCTCACGACCAAAGGACCAGTCCCCCCCCCCCCTCAGGATCTAAGCAGAAAATGCGT TCAACAGACTGTAGATATTGTCTGAAGCTCTGAGAGAAAGCTTTGAAGAAGTAATTATGCAAAGCTGTCT TACATTAATAGATGATGGCTGCCCCAAGGACAAGTCAGGAGCTGGATGGATTTGTGGGTTTAAAACGGTT TGCTGGCAGACACGCAATCGCAGCGGTCTCCTTTTGATTTCCACACATAGGTATGTAGCATGTGCTAAAT ATTTAGACAAGAAACAAGAAATGGAAGTCGAGGTTACTTGTTCTGCTCAGTTCCCCAAGGGCAAGGAACC TTGTTTGTCCCTTTAGTCATTAGCAATGGAGACCCACGTGTCCCTGTTACTACACATACTTTGAAAAGAT CTGCTAACCTGGAGTCATCAAGTTTCAGGAGCCCTTTGTAAAATTCAGCCAGTGTCTTAGAAACCTGTAC TGTCCCCAAACAATGCCAGTTAGTGGTGTATTTATGTAGCAGTGTAAGCAAAGTTACACATCAAAGTTGC ACTGCTTGTACCAACCGTGACATAGTAGGTATATCAGCTTTAGTTCACATCTGAGAAACATAAACAGTCG GTGGTGAATAGACTACATATCATACAATCTGCCTTGTTCTCTAAAAGTATATATCCTCCACATATATGTA CATATGTATCTCTAAGCTGTCATTTGATGAAGTTTTGGCAATGTATGTTTACCTCTAAATAAAGTAATTT TATTGTAACGTAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_177322 |
| Insert Size | 1080 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC036175, AAH36175 |
| RefSeq Size | 2198 bp |
| RefSeq ORF | 1080 bp |
| Locus ID | 11607 |
| UniProt ID | P29754 |
| Gene Summary | Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.[UniProtKB/Swiss-Prot Function] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
The Nox1/4 dual inhibitor GKT137831 or Nox4 knockdown inhibits Angiotensin-II-induced adult mouse cardiac fibroblast proliferation and migration. AT1 physically associates with Nox4
,null,
Journal of cellular physiology
,PubMed ID 26445208
[Agtr1a]
|
|
CIKS (Act1 or TRAF3IP2) mediates Angiotensin-II-induced Interleukin-18 Expression, and Nox2-dependent Cardiomyocyte Hypertrophy
,null,
Journal of molecular and cellular cardiology
,PubMed ID 22575763
[Agtr1a]
|
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG205480 | Agtr1a (tGFP-tagged) - Mouse angiotensin II receptor, type 1a (Agtr1a) |
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| MR205480 | Agtr1a (Myc-DDK-tagged) - Mouse angiotensin II receptor, type 1a (Agtr1a) |
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| MR205480L3 | Lenti ORF clone of Agtr1a (Myc-DDK-tagged) - Mouse angiotensin II receptor, type 1a (Agtr1a) |
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| MR205480L4 | Lenti ORF clone of Agtr1a (mGFP-tagged) - Mouse angiotensin II receptor, type 1a (Agtr1a) |
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