Elavl1 (NM_010485) Mouse Untagged Clone
CAT＃: MC201277
Elavl1 (untagged) - Mouse ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (Elavl1), (10ug)
CNY 3656.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2410055N02Rik; Hua; HUR; W91709 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC016194 sequence for NM_010485
CGCGCGGAGCGGGAGCCGCCTCGGGGAGAGCGCGGACAACCAGGGTGTTTGTGAGAGCTGGGGCGGGGGT TGGGACGCCTGGCCGGCATGGCTGGAGGCTGCGCTCCGCAACCTTGAGGAACTGTGCGGCCTTCCCGCCC GTGTTCAGGTTATTATCGATAAAACAGCTGTCTGTAAACATAGTTGATCTCCTTGTATGAATATAGATTT TTAAATAATACAATGTCTAATGGTTATGAAGACCACATGGCGGAAGACTGCAGGGATGACATTGGGAGAA CGAATTTAATTGTCAACTACCTCCCTCAGAACATGACCCAAGAGGAACTACGAAGTCTGTTCAGCAGCAT TGGCGAGGTTGAATCTGCAAAGCTTATTCGGGATAAAGTAGCAGGACACAGCTTGGGCTACGGTTTTGTG AACTATGTGACTGCAAAAGATGCAGAGAGAGCAATCAGCACACTGAACGGCTTGAGACTCCAGTCCAAAA CCATTAAGGTGTCATATGCTCGCCCAAGCTCAGAGGTCATCAAAGATGCCAACTTATACATCAGTGGGCT CCCAAGGACCATGACACAGAAGGATGTGGAAGACATGTTTTCTCGGTTTGGGCGAATCATCAACTCCAGG GTCCTTGTGGATCAGACCACAGGTTTGTCCAGAGGGGTTGCCTTTATCCGGTTTGACAAACGGTCAGAAG CAGAAGAGGCAATTACCAGTTTCAATGGTCATAAACCCCCAGGTTCCTCCGAGCCCATCACAGTGAAGTT TGCAGCCAATCCCAACCAGAACAAAAACATGGCTCTCCTCTCGCAGCTGTACCACTCGCCTGCTAGGCGG TTTGGAGGCCCTGTACACCACCAGGCACAGAGATTCAGGTTCTCCCCTATGGGTGTAGATCACATGAGTG GGATTTCTGGTGTCAATGTCCCCGGCAATGCTTCCTCGGGCTGGTGCATCTTCATCTACAACCTTGGGCA AGACGCCGATGAGGGGATCCTCTGGCAGATGTTTGGCCCCTTTGGTGCAGTTACCAATGTGAAAGTGATT CGTGATTTCAACACCAACAAGTGCAAAGGGTTTGGTTTTGTGACCATGACAAACTATGAAGAAGCTGCAA TGGCCATAGCAAGTCTGAACGGCTACCGCCTGGGGGACAAAATTTTACAGGTTTCCTTCAAAACCAACAA GTCCCACAAATAACTCGCTCATGCTTTTTTTTTTCTTTCCTTCTTTTTTTTTTCCTTTTCTTTTTTCTTT TTTTGTACGGAATAGATAATTAAGAGTGAAGAAGTTGAAACTTTTTTGTTAGTGTACAACTCATTTTGCG CCAATTTTCACAAGTGTTTGTCTTAGTCTAAATGAGAAGTGCAAAGGTTTTTATACTCTGGGATGCAACC GACATGTTCAAATGCTTGAAATCCCACAAATGTTAGACCAATTTTAAGTTTCTTAAGTTATTTCCTTTAA AGTATATATTAAAGTGAAACCGAAGTAGACTGCGCTGACTAACCAGTCACTCTGGACGGTGGTGGGACTG AAGCATGCTTTTACTTCTAAGACTGTCTAACACCTGTTTCATCTGATGTCTCCACAGACTGGATTTAAAA CAAAACAAAAAAAATTTTTTTTTAATTTCTTTGTTTTAGTTTTTAACCTAAAGATGTTAGACAGATGGGG AGTGTGTTTTTTCTCAACTGCTTCACTATTTTAAACAATTTCTGCTTTAGGTGACAGGAAATTTGCCCTC CCCAGCAGTCCCACTGCTGCCCCCTGCCCACTCAGTCCCAGCTCTATAGTGTTGGGAGCAGCAGCAGGGC CCATATTCTGGGGCTCCCACAAGGGGAGATGGGAAGAGGTTCCACATGTTGGGCTGAGCCAGGCCCTCCA GAGACACAAAAGGTGTTTTGTAAGCCCAGGCACCAATGAGAACGGACCAAAGAGTTTCAGGGCAGCTCCA GTATATTCCAGAGTCAAACCTGAGCTCCAGGCATGCCTGAAGATGCCCCACTCCTCTGACATCCTGAGCG TCTGTCCACACATTGCATGCATGGTGCCCACACATCAGATACTGTTGTTCATGCAACTTCCCGAGTTTCC AAGACCATTTAACCTAGCTTGAATGCACAACGATTGCTCTGTTTTTAATGACACAGAAACATTTGAGCAT TGTATTTTCTCGCATCCCTTCTTGTGAGCACTAGACTTTTTCCAATCTTAGTCAGATTTTGCTTTGAAAT TTTGCTTTTGTATGGACACTCAGCAGAAAAGTACTTCTTGCCAGTTATCTATTAACAAAATCCTTTGATT TGTAGTTTTAAGGATTAACCCTCAAAGTTCTCTTCATAACTGCCTTGACGTTTGGGGTTCTGTTCTGTTA ATTTTCTTTTGCTTTTTTGTGTTTTTTGTTTGTTTTTACTTTTGCATTTAAGACCATTAAATTTGATTTT GTTTTGCTCGAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_010485 |
| Insert Size | 1146 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC016194 |
| RefSeq Size | 2475 bp |
| RefSeq ORF | 1146 bp |
| Locus ID | 15568 |
| UniProt ID | P70372 |
| Gene Summary | RNA-binding protein that binds to the 3' UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation (PubMed:24394384). Binds to poly-U elements and AU-rich elements (AREs) in the 3' UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro (By similarity). With ZNF385A, binds the 3' UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A anti-proliferative activity. May also bind with ZNF385A the CCNB1 mRNA (PubMed:21402775). Increases the stability of the leptin mRNA harboring an AU-rich element (ARE) in its 3' UTR (PubMed:27616329).[UniProtKB/Swiss-Prot Function] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG225411 | Elavl1 (tGFP-tagged) - Mouse ELAV (embryonic lethal abnormal vision Drosophila)-like 1 (Hu antigen R) (Elavl1), (10ug) |
CNY 2850.00 |
|
| MR225411 | Elavl1 (Myc-DDK-tagged) - Mouse ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (Elavl1) |
CNY 2400.00 |
|
| MR225411L3 | Lenti ORF clone of Elavl1 (Myc-DDK-tagged) - Mouse ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (Elavl1) |
CNY 4750.00 |
|
| MR225411L4 | Lenti ORF clone of Elavl1 (mGFP-tagged) - Mouse ELAV (embryonic lethal, abnormal vision, Drosophila)-like 1 (Hu antigen R) (Elavl1) |
CNY 4750.00 |
