SORCS3 (NM_014978) Human 3' UTR Clone

Specifications

Product Data
Product Name	SORCS3 (NM_014978) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SORCS
ACCN	NM_014978
Insert Size	1898 bp
Sequence Data	Insert Sequence (showhide) >SC216779 3’UTR clone of NM_014978 The sequence shown below is from the reference sequence of NM_014978. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGGAGATCCCCAACTGCACTAGTGTTTAATACCAGCAAGCCACGTGGTCAACCACCTTTCTGACTTTT TATTTTTGATGATTACTATTACTATTATTATGGAAAAATTAAAATGTCTTTTTTACCTTTTGTTTACCA AGGGCCCCTTCATAAATAGCAGGCAAATGCCTAGCTTTGGGAGAAAAGGGCATTCTTAGCTGATTGAAA TGAGACAAAGGGAATAAATGGCTGTATTTGTGCTAAGAGCAAAGGATGCATCTTCCCACAGCCTCCTCG CTTTACTCTGCCATTGGTAGCTTAAAGACTTTCTTTTTCCTTGTGGTCTCCCTTTTTTCAAAATTGAAG TTGGGTTGGCTCTTTGTGAACCTCTCATCCCCACAGCAGAATCACCAACACTCTCCGCTTCCCCCAGCA CACACACATACAACACAGATCATTTCCCAGTTAGATCCGCAGGAAGTAGGTTGGTGGGGGTGGATGTAG CTGCAGAAAGCATGCACAACTTTGTGAAAGAGGCCCTGCCTTGTGCATGTCCATAGTGAGGCTACAGAT GGCTTATTGTATATAATTACAATGTAAATAGCTTTTTATTTCCTAAGAAATAATTTAATGTTTAGTAAA AAAGAAAACAGAAAAAAGAAAGATGCGTGTGTTGGCTTACGCACTGGCCCTCAGAGCTGACCAACCCGC CAGGCCTGCTCAATGCATTGGGTTTGGATGCTCTCCTGTTGTCTGTCACACTTAACTCTTGCATCTCCT TGTCCATGCCATAGCTGGTTTCTACTTATGTATATAAAGGGGGGTGGGGGGAGGGGCTTCTCTGGGGCA ATTGATAAAGGAAGGACTCTAGTGACATCATAGAACATGGCAGTCGTTTTTGTTCCAAGAATGATATGA AAGGTGAAGAAGAGGCCCACTAGAGGCTTCATACTGAGACCCAGATGGGGGAAAACAGCTTCCTCTCTA AAAGGAAAAACTTGATATTTATCAGTCTGAGAAAATATTTTTTTCTAAAGAAGGCAGTCAGTGGATCTT AAAATGACAATCTGTTTTTAAATTGGATTCTATGAAAATGCATAATGCTTATGGTGAATTCTCAGGCTA TTCTGAGCTCAGAAAAGTCCCCTGGGCACTAGGTAAAGCCCAGTGAATGTCTCTTGGCATGGGAGGAGT TAAAGAGGTTGGAAGGGAAGAGGCATTTGTGGAATTATGAGTTCATGCAAAACTCTCCAGGCCAAGTAG GGGTCTAGCCTTTAATGATATTAGTCAAAGGCAATTTTAGCAAAGCTGTGCTATTTGCTTGTCAGATGT ACACAACTTCCTTAAAGTCAAATGTCTGCCTTCAGTTCCCTTAAGGTAGTTCTTGCCTCTGGGGTGAGT GGCTTTCAAAGCCTTTTAGCTTTTCCAGCACCTCAGCCCCTTCACACATTTACACATACCAATTTTTTT CAATAGGGTCACGTTAAGCCATGCTGTAAGCATTGTTTTTATTTTCAGGCTTAGCCTGAGCACACTTAT TTTTGAAAATGATATAATGTATATATATGGGAGGAAAGGCCACATTTTGTACCTGTTAATTTTTGTGGG ATGTTGTTCCCATTCTTCTTTGTGAGACAGAGAGAATGTGATATAGAGAAATCTGGCTGGCTACAGTGT AGATCAGTATTAGGAATATTTCTAAAGATCCTGCTTTTTTGTTTCAAGGGTTAAATGGGGCAGACAATT GCAATACTTGTACTAAACACTGGAATACAAATGCATGACTCATATCTATATATACAGTATATGTACATA TACTGTTCTTGGTTTTATTGTTCCACTTGAATATTTCTACTGTAAAAAAAAGACAGTGGTTTTGAAATT GTTGAAAATAAATGTATTTTTGTACATCAAAGCTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014978.3
Synonyms	SORCS
Summary	This gene encodes a type-I receptor transmembrane protein that is a member of the vacuolar protein sorting 10 receptor family. Proteins of this family are defined by a vacuolar protein sorting 10 domain at the N-terminus. The N-terminal segment of this domain has a consensus motif for proprotein convertase processing, and the C-terminal segment of this domain is characterized by ten conserved cysteine residues. The vacuolar protein sorting 10 domain is followed by a leucine-rich segment, a transmembrane domain, and a short C-terminal cytoplasmic domain that interacts with adaptor molecules. The transcript is expressed at high levels in the brain, and candidate gene studies suggest that genetic variation in this gene is associated with Alzheimer's disease. Consistent with this observation, knockdown of the gene in cell culture results in an increase in amyloid precursor protein processing. [provided by RefSeq, Dec 2014]
Locus ID	22986
MW	72.5

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