Factor VIII (F8) (NM_019863) Human 3' UTR Clone

Specifications

Product Data
Product Name	Factor VIII (F8) (NM_019863) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AHF; DXS1253E; F8B; F8C; FVIII; HEMA
ACCN	NM_019863
Insert Size	1835 bp
Sequence Data	Insert Sequence (showhide) >SC216617 3’UTR clone of NM_019863 The sequence shown below is from the reference sequence of NM_019863. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGGGCTGCGAGGCACAGGACCTCTACTGAGGGTGGCCACTGCAGCACCTGCCACTGCCGTCACCTCTC CCTCCTCAGCTCCAGGGCAGTGTCCCTCCCTGGCTTGCCTTCTACCTTTGTGCTAAATCCTAGCAGACA CTGCCTTGAAGCCTCCTGAATTAACTATCATCAGTCCTGCATTTCTTTGGTGGGGGGCCAGGAGGGTGC ATCCAATTTAACTTAACTCTTACCTATTTTCTGCAGCTGCTCCCAGATTACTCCTTCCTTCCAATATAA CTAGGCAAAAAGAAGTGAGGAGAAACCTGCATGAAAGCATTCTTCCCTGAAAAGTTAGGCCTCTCAGAG TCACCACTTCCTCTGTTGTAGAAAAACTATGTGATGAAACTTTGAAAAAGATATTTATGATGTTAACAT TTCAGGTTAAGCCTCATACGTTTAAAATAAAACTCTCAGTTGTTTATTATCCTGATCAAGCATGGAACA AAGCATGTTTCAGGATCAGATCAATACAATCTTGGAGTCAAAAGGCAAATCATTTGGACAATCTGCAAA ATGGAGAGAATACAATAACTACTACAGTAAAGTCTGTTTCTGCTTCCTTACACATAGATATAATTATGT TATTTAGTCATTATGAGGGGCACATTCTTATCTCCAAAACTAGCATTCTTAAACTGAGAATTATAGATG GGGTTCAAGAATCCCTAAGTCCCCTGAAATTATATAAGGCATTCTGTATAAATGCAAATGTGCATTTTT CTGACGAGTGTCCATAGATATAAAGCCATTTGGTCTTAATTCTGACCAATAAAAAAATAAGTCAGGAGG ATGCAATTGTTGAAAGCTTTGAAATAAAATAACAATGTCTTCTTGAAATTTGTGATGGCCAAGAAAGAA AATGATGATGACATTAGGCTTCTAAAGGACATACATTTAATATTTCTGTGGAAATATGAGGAAAATCCA TGGTTATCTGAGATAGGAGATACAAACTTTGTAATTCTAATAATGCACTCAGTTTACTCTCTCCCTCTA CTAATTTCCTGCTGAAAATAACACAACAAAAATGTAACAGGGGAAATTATATACCGTGACTGAAAACTA GAGTCCTACTTACATAGTTGAAATATCAAGGAGGTCAGAAGAAAATTGGACTGGTGAAAACAGAAAAAA CACTCCAGTCTGCCATATCACCACACAATAGGATCCCCCTTCTTGCCCTCCACCCCCATAAGATTGTGA AGGGTTTACTGCTCCTTCCATCTGCCTGACCCCTTCACTATGACTACACAGAATCTCCTGATAGTAAAG GGGGCTGGAGACAAGGATAAGTTATAGAGCAGTTGGAGGAAGCATCCAAAGATTGCAACCCAGGGCAAA TGGAAAACAGGAGATCCTAATATGAAAGAAAAATGGATCCCAATCTGAGAAAAGGCAAAAGAATGGCTA CTTTTTTCTATGCTGGAGTATTTTCTAATAATCCTGCTTGACCCTTATCTGACCTCTTTGGAAACTATA ACATAGCTGTCACAGTATAGTCACAATCCACAAATGATGCAGGTGCAAATGGTTTATAGCCCTGTGAAG TTCTTAAAGTTTAGAGGCTAACTTACAGAAATGAATAAGTTGTTTTGTTTTATAGCCCGGTAGAGGAGT TAACCCCAAAGGTGATATGGTTTTATTTCCTGTTATGTTTAACTTGATAATCTTATTTTGGCATTCTTT TCCCATTGACTATATACATCTCTATTTCTCAAATGTTCATGGAACTAGCTCTTTTATTTTCCTGCTGGT TTCTTCAGTAATGAGTTAAATAAAACATTGACACATACAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_019863.3
Synonyms	AHF; DXS1253E; F8B; F8C; FVIII; HEMA
Summary	This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
Locus ID	2157
MW	71.4

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.