Cytochrome P450 2B6 (CYP2B6) (NM_000767) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cytochrome P450 2B6 (CYP2B6) (NM_000767) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450
ACCN	NM_000767
Insert Size	1601 bp
Sequence Data	Insert Sequence (showhide) >SC215362 3’UTR clone of NM_000767 The sequence shown below is from the reference sequence of NM_000767. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACATACCAGATCCGCTTCCTGCCCCGCTGAAGGGGCTGAGGGAAGGGGGTCAAAGGATTCCAGGGTCAT TCAGTGTCCCCGCCTCTGTAGACAATGGCTCTGACTCCCCGCAACTTCCTGCCTCTGAGAGACCTGCTA CAAGCCAGCTTCCTTCCCCTCCATGGCACCAGTTGTCTGAGGTCACATTGCAAGTGAGTGCAGGAGTGA GATTATCGAAAATTATAATATACAAAATCATATATATATATATGTTCTTGTTTTTTGAGACAGAGTCTC ACACTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCCACCCCCGGGGATCA AGCAACTCTCCTGCCTCAGCCTCCCTAGTAGCTGGGATTACAGGCATGCACTACCACGCTTGGCTAATT TTTGTATTTTTAGTAGAGATGGGGTTTCACTGTGTAGGCCAGGCTGGTCTCGAACTCCTGAACTCAAGT GATTCACCCACCTTAGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGTCACCGTGCCCAGCCATGTATA TATATAATTTTAAAAATTAAGCTGAAATTCACATAACATAAAATTAGCTGTTTTAAAGTGTAAAATTTA GTGGCGTGTGGTTCATTCACAAAGCTGTACAACCACCACCATCTAGTTCCAAACATTTTCTTTTTTTCT GAGATGGAGTCTCACTCTGTCACCCAGGTTCGAGTTCAGTGGTGCCATCTCTGTCCACTGCAACCTCCA CATCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCTGGAGGAGCTGGTATCACAGGCGTCCCCCACCA CGCCTGGCTAAATTTTGTATTTTTAGGTGGTCTTGAACTCCTGATGTCAGGTGATTCTCCTAGCTCCAA ATGTTTTCATTATCTCTCCCCCAACAAAACCCATACCTATCAAGCTGTCACTCCCCATACCCCATTCTC TTTTTCATCTCGGCCCCTGTCAATCTGGTTTTTGTCACTATGGACTTACCAATTCTGAATATTTCCCAT AAACAGAATCATACAATATTTGATTTTTTTTTTTTTTTTGAAACTAAGCCTTGCTCTGTCTCCCAGGCT GGAGTGCTATGGTGCAATTTTTGTTCACTGCAACCTCTGCCTTCCAAGATCAAGAGATTCTCCAGTCTC AGCTCCCAAGTAGCTGGGATTACAGGCATGTACTACCATGCCTGGCTAATTTTCTTGTAGTTTTAGTAG GGACATGTTGGCCAGGCTGGTGGTGAGCTCCTGGCCTCAGGTGATCCACCCACCTCAGTGTTCCAAAGT GCTGATATTACAGGCATAATATGTGATCTTTTGTGTCTGGTTGCTTTCATGTTGAATGCTATTTTTGAG GTTCATGCCTGTTGTAGACCACAGTCACACACTGCTGTAGTCTTCCCCAGTCCTCATTCCCAGCTGCCT CTTCCTACTGCTTCCGTCTATCAAAAAGCCCCCTTGGCCCAGGTTCCCTGAGCTGTGGGATTCTGCACT GGTGCTTTGGATTCCCTGATATGTTCCTTCAAATCTGCTGAGAATTAAATAAACATCTCTAAAGCCTGA CCTCCCCACGTCAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000767.5
Synonyms	CPB6; CYP2B; CYP2B7; CYP2B7P; CYPIIB6; EFVM; IIB1; P450
Summary	This gene, CYP2B6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to metabolize some xenobiotics, such as the anti-cancer drugs cyclophosphamide and ifosphamide. Transcript variants for this gene have been described; however, it has not been resolved whether these transcripts are in fact produced by this gene or by a closely related pseudogene, CYP2B7. Both the gene and the pseudogene are located in the middle of a CYP2A pseudogene found in a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
Locus ID	1555
MW	59.5

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