RIZ1 (PRDM2) (NM_001007257) Human 3' UTR Clone

Specifications

Product Data
Product Name	RIZ1 (PRDM2) (NM_001007257) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	HUMHOXY1; KMT8; KMT8A; MTB-ZF; RIZ; RIZ1; RIZ2
ACCN	NM_001007257
Insert Size	1584 bp
Sequence Data	Insert Sequence (showhide) >SC215295 3’UTR clone of NM_001007257 The sequence shown below is from the reference sequence of NM_001007257. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGCTGAAGGACTTCAGGAACTTCCTGTAGAAAAGCCCCCAAAACAAAACAAACCTTAATTGACTAAAA AGTATTGCATGCTCAACTTAGGATAAGCACTACGGCAAAGGATACGAAATCTACCAAGCTTGCAAGACC AGTTGAAGCTGACTCAAAAATCCTAACATTCAGCTGATTGCCGGCAGGCTTAGAGTCAGGCATCTGCTG CTTCGGTGGGGGCCCAACGCGCATGCTGGGCGCCCGGGTGATTGAGATCCAAAGAGAAGGGCACTGTAA GACAGGCCAGATGAACTGGCTCCTCGTCATGGGACTGGTACCTCAGATCTGAGCATGGCCCTTGTTTTT GGCACGTAGCAGAGAAAGGATTGATTTGAACTTAACCTTGCAAAGCAAGTTGCCTGTTTTAGCAGTAGT TTGTTGTAGGTTTCAGGGATGACAGATTTGGATGCACTCATTTAAAACGTTTTGGTCACATATCAGCTC TTGATGCCTTTCTTTTAAATTAATTATAGACAGAGAGAGGCATTTAGCTGATCTCTTACCCCTGGTATT TCTTTTTTTTGTTGTTTTCGTTTTTTTAAATCACAAGTAGATTGCCAGCGTAATGGAGAGGAAACCAGA TTGGATATGGACTCTTTTTTATGCCTATTCTGGTGTTGCGTTTGTATATCCAAATGGACGTTATCCTCT CAGATTCTTATCTGGCACTAATTTATAACTATTATATTATCAGAGACTATGTAGCAATATATCAGTGCA CAGGCGCATCCCAGGCCTGTACAGATGTATGTCTACACGTAAGTATAAATGAATTTGCATACCAGGTTT TACACTTGCATCTCTAATAGAGATTAAAAACAACAAATTGGCCTCTTCCTAAGTATATTAATATCATTT ATCCTTACATTTTATGCCTCCCCCTAAATTAATGACTGAGTTGGTGGAAAGCGGCTAGGTTTTATTCAT ACTGTTTTTTGTTCTCAACTTCAAAAGTAATCTACCTCTGAAAAATTTGTAGTTTAATATTTGTTTGGT GAATTTGTGCCACTTTAATCCTTCCACTATCATTCCCATTTTGTTACATTTCTGTTATGGGGACTTTAT GTTGAAATATTGTATAAAGCATTTGTAGCAATTTAAAAATAAAATATTTAAAATTATTTAAATTGTTTT GGACGCTTCAATTGTATTATATGTGATTTACATTTCACTTTTTTTGTTGGCGTTGTTAACCCGGAGAGT GCTCCTGTATTGAACTTTGCTGTTAGTTATTTTATTGCTTCTTTTTGGAGAGTGCTATAAAAGACTATT CTAATGAAAACATTAAAATTTACAATTTGACATACAAAAAGGGGTTGTCCATTGATTTTAACCAATGTA GCACTGAGAGAGAGAGAGGTTAATTATAGATAGACAAGAGTGGTGTTTGTTGTTTTTCCCCTCCCAGCA TTGAAATCATTGGGGCTTGTCAGATGTATTAAAAAAAGATTTGTTGTGCTATTGCTGCAAACACTTAAT AACTAGAGGAGAATTTAAACAATGCATTTTATATTATTGTAACCAATAAAAAACTTTCTAAACATC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001007257.3
Synonyms	HUMHOXY1; KMT8; KMT8A; MTB-ZF; RIZ; RIZ1; RIZ2
Summary	This tumor suppressor gene is a member of a nuclear histone/protein methyltransferase superfamily. It encodes a zinc finger protein that can bind to retinoblastoma protein, estrogen receptor, and the TPA-responsive element (MTE) of the heme-oxygenase-1 gene. Although the functions of this protein have not been fully characterized, it may (1) play a role in transcriptional regulation during neuronal differentiation and pathogenesis of retinoblastoma, (2) act as a transcriptional activator of the heme-oxygenase-1 gene, and (3) be a specific effector of estrogen action. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
Locus ID	7799
MW	61.1

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