TAOK1 (NM_020791) Human 3' UTR Clone

Specifications

Product Data
Product Name	TAOK1 (NM_020791) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	hKFC-B; hTAOK1; KFC-B; MAP3K16; MARKK; PSK-2; PSK2; TAO1
ACCN	NM_020791
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC214715 3’UTR clone of NM_020791 The sequence shown below is from the reference sequence of NM_020791. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCAATGGGTCACACATGTCTTATACATAACTTAATAATTGAGAGTGGCAATTCCGCTGGAGCTGTCTG CCAAAAGAAACTGCCTACAGACATCATCACAGCAGCCTCCTCACTTGGGTACTACAGTGTGGAAGCTGA GTGCATATGGTATATTTTATTCATTTTTGTAAAGCGTTCTGTTTTGTGTTTACTAATTGGGATGTCATA GTACTTGGCTGCCGGGTTTGTTTGTTTTTGGGGAAATTTTGAAAAGTGGAGTTGATATTAAAAATAAAT GTGTATGTGTGTACATATATATACACACACATACACATATATTATGCATGTGGTGAAAAGAATTGGCTA GATAGGGGATTTTTCTGAACACTGCAAAAATAGAACGTAGCAAAATGGCTTCAGTTATCACTTTTGGGT GTCTGTATCCTAAGAAGTTTCTGAAAAGATCTAAAGCCTTTTTATCCCATATCCCAAATTCTTATGAGC CACTCACAGCAGGCAGCATATGTTGAAATAAGTTATTACTGGTACACACCTGCATTGCCTCACCAGTGT ATTTATTTGTTATTAAATTGATCTGACTTCTCAGCCTCATTTGGACTAAAAAAAGAAAGCAGAAATCCA TGAACACATTGCTTCTCGGCCTTTTGGCTAAGATCAAGTGTAGAAATCCATGAACACTAAAGGACTTCA TTGATTTTTTCAGAGAGTAGAAAACAACTTAGTTTTTCTTTTTTCCTGAATGCGTCATAGGCTTGTGAG TGATTTTTGTCCATTCAATTGTGCCTTCTTTGTATTATGATAAGATGGGGGTACTTAAGGAGATCACAA GTTGTGTGAGGATTGCATTAACAAACCTATGAGCCTTCAATGGGGAAGACCAGAAGGGTGAGAGGGGCC CTGAAAGTTCATATGGTGGGTATGTCCCGCAGCAGAGTGAGGAGATGAAGCTTACGTGTCCTGACGTTT TGTTGCTTATACTGTGATATCTCATCCTAGCTAAGCTCTATAATGCCCAAGACCCCAAACAGTACTTTT ACTTTGTTTGTACAAAAACAAAGACATATAGCCAATACAAATCAAATGCCGGAGGTGTTTGATGCCATA TTTGCAAATTGCCATCTATTGAAATTCTCGTCACACTACATAGACATAATTGTTATCTCCTTTTGGCTT ATGTGATTTTCTGTTTACAAGTAGAATAGCCAATTATTTAAATGTTTAGTTGCCACAGTGAACCAGGAG TCACTGAGCCAATGACTTTACCAGCTGCTGACTAATCTTCATCACCACTGTAGATTTTGCTGCATGTGC AGGTCCTCTATTTTTAATTGCTGTTTTCGTTGCTGCAGTACTTTACAAACTTCTAGTTCGTTGAGACTT AGTGACCATTTGGCATCAAGTTAACATCACACAATAGGAAACACCACTTCCACAAGTCTCAAGCCTCAG TGCTAAAGTACTACTGAAAAGGAACTAGGAAGTTTGGCCAATTAAAAAAAAAAAGTAAAATAAGTTATA GTGGTCAGGGAATCTCTTGACGAAAGCTAACTCTTATTTTTCAGGGGGCACATGTTTTGTTTTGTTATG TTTTGTTGTACAATGAAGGATGAACCCAATGCTAAAAAGTCAGTTATTTTCTTGGTTTTCCATTTCTTG TATATAAATTGTGTTGGAGGTGGGTAGGAAGCTGTGAGTATGACTTGAAGAAAAATATCCTTTTCAGTG ACAAATCAGAGTTTCTTACAAGTTATTGTCCTGCTCCCTTCCAAGTTGTCTTGAAGAATCCTTGCTGCT AACTCTGGATCCTGCTTTTCCTATAGTCAGAGGGCTCCAAGGTAGAACTCTCTAAGTCCCTCTCAATGG CACTCTTTGCCTAGACCAAACTAATGACCAAACAGTAATCAATCTATCACTGTTGAAGTCCTGGTTTTC TCAACCAAATTTTAAGTCTTTCCCAGGTATGTCAGTCGAGTTGCCATGAATCCTCACCTGTAGGAGTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_020791.4
Synonyms	hKFC-B; hTAOK1; KFC-B; MAP3K16; MARKK; PSK-2; PSK2; TAO1
Summary	Serine/threonine-protein kinase involved in various processes such as p38/MAPK14 stress-activated MAPK cascade, DNA damage response and regulation of cytoskeleton stability. Phosphorylates MAP2K3, MAP2K6 and MARK2. Acts as an activator of the p38/MAPK14 stress-activated MAPK cascade by mediating phosphorylation and subsequent activation of the upstream MAP2K3 and MAP2K6 kinases. Involved in G-protein coupled receptor signaling to p38/MAPK14. In response to DNA damage, involved in the G2/M transition DNA damage checkpoint by activating the p38/MAPK14 stress-activated MAPK cascade, probably by mediating phosphorylation of MAP2K3 and MAP2K6. Acts as a regulator of cytoskeleton stability by phosphorylating 'Thr-208' of MARK2, leading to activate MARK2 kinase activity and subsequent phosphorylation and detachment of MAPT/TAU from microtubules. Also acts as a regulator of apoptosis: regulates apoptotic morphological changes, including cell contraction, membrane blebbing and apoptotic bodies formation via activation of the MAPK8/JNK cascade.[UniProtKB/Swiss-Prot Function]
Locus ID	57551
MW	77

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