GFI1 (NM_005263) Human 3' UTR Clone

Specifications

Product Data
Product Name	GFI1 (NM_005263) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GFI-1; GFI1A; SCN2; ZNF163
ACCN	NM_005263
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC213690 3’UTR clone of NM_005263 The sequence shown below is from the reference sequence of NM_005263. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CACCGGGAGACGCAGCATGGGCTCAAATGAGCACCCTGGCTGGCTGCAAGCAGCAGCTACACAACACTA CAGAGGGCAGCCTCCCTGCTTGCCACCACTCTGCTCCCTGCTTGCCTCCACTCCCTTCTGACTTTCCAG ACCCCAGGTCCAGTCTGCAGATCCTACCAGGTTGCTCCTCCTTCGCCTTACCTCCTGGAGCTGCCAGAA GAAATGAGGTACCTTTTCAAAGTGCAGCCGAGAGTGAGAACCAAGTGACTCTCTAGGCTTCGGACACAA ATAGGCTCCTCTACACCTGAAGACAAAGGCAAAGTCAAATGGGGACCAGAATAAATCTTAGACCCCACA GTCCTTCCCATTTCCAGCCCTAATCTACAGACAGGAATGCCCTTCAGGTTTCTTCCCTCCCCCCTCTTG ACCTACCCCAGATATTTGTGTGGAAGAGGAGGAATCACCATTTACAAGGTGGACAAATGCTAATATTTT TATCTAGAAAGAAGAGTGAGTGTTAACTTTTATTTTTTTCCTTCTGGGGGGTCTGTTGACTCCTTTCTT TTGGGTGCTGCCTATAAATCTTGGAGGAATCATTTCTCCTCCTCAAAAACTGATTCAGAAACTGACTTG GGGAAGGAATTTAATACTTTGAAGTCATGAGATGCACCATCGAGGCTACCCCCAAGAAGAAGCAGAAGA GAAGTTGGTAATGAGAGGGGATTAGAGGTCCTCCCTTCAGTAGGGCTGTGAAAACCTCATCACTGGAGG TAAAAGCACAAGCAATGCCTGTGGACAAGATGTCATTCATTCACTCAGCAAATGTTCATGGATCACCGG CTACCAAGGTACCAGGCACCATGCTAGGTATTGGGGAAGAGAGACTGAAGTCACAACCCCTGACTGCTC CTCAAAAGCTAACGGTTGCACCTCCAAGTGGCTGGGTCTGTTCTTACTCTTGGAGGGAATTCTGAGAAG ACAGCACAGAATTGTAAACCTTCCCTTTTGACCCTTTTGGATTTTATCAGGTGTAAACAAAAAGCTGAA CAGTTACTTCAAAGATATGTGTGTATATTCAGTTTTTTATTGTTAAGCTGATATTTTAAAGATTTCTGA GCTAGCAGGCATGTGGGAAGGAAGGCTCTGTCTTCAACTCTTTGACCCTCCATGTGTACCATAGAGGGG GGAAAGGTGGTATTTTCACTTTGATGAGGTTGGTAAATGTTTTTAGATCTTCTGGTAAGCATTATGTTT GTTAATACATATTTATTAGAGTGATGTTTTAAGTTAATAAAGTATTAAGAGTATTACAGATTGCCTTTC CTTTAGGCAGGGAATTTGGGGAAGACCTTTGTTTTAGTCTGTAGGGGGAAAGCTGGCACTGAAGGAAAC TGCAATGGAGTATAAAAGTGAAGCACACAAGCTAATATCCAGAAGAGTAAAATCCAATTGCTCGGGTTT CCATATACTTTCTCCTTTGCTGCTACACCTCAGAGATACTTCTTTCATCTTCTTTCATAAGAGAAAAAC TAGGAGGTGTACAAAACTAAGCTACTACCTTGTAGAGCCCCTGATGGTTCCACAGGCACGTAAGTAAGC TCTTTCCTCTGAAAATGTCAACATATTTTTTTAGGGGCCTGAAGGCTCCCAGATGAATAAAGAAATCAC AGGTCTTAGGTCTAGGTTTTAGTTTTAGTCACAGCTCTGTCACCAACACATCATGTGACTTGTGTAAAT CTTTTGACTTCCCCGATACTGGTTTCCTTGATCAAGTAATACGGAGACAGCTCTGTCATTCCTGTCCAA CCCTGACCGCTTTGATTCTGTGGAGACTGGAAAGGAAAAAAAGTGTGAGATTGGTTAGCTGCCTCCCCT AATGCAAGTCACAAATCTAAAGGCCCATGAGGATCTGGGTTATTTCTGGTTCTGTCCCACCTGTGGGAG TTTTTTGCATAAGTCAATCCTTTAAGAGAATGAAACCAGAATAAAATCCTGGCCAAAATCCCTACTAC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005263.5
Synonyms	GFI-1; GFI1A; SCN2; ZNF163
Summary	This gene encodes a nuclear zinc finger protein that functions as a transcriptional repressor. This protein plays a role in diverse developmental contexts, including hematopoiesis and oncogenesis. It functions as part of a complex along with other cofactors to control histone modifications that lead to silencing of the target gene promoters. Mutations in this gene cause autosomal dominant severe congenital neutropenia, and also dominant nonimmune chronic idiopathic neutropenia of adults, which are heterogeneous hematopoietic disorders that cause predispositions to leukemias and infections. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
Locus ID	2672
MW	75.3

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