P2RX7 (NM_002562) Human 3' UTR Clone
CAT#: SC213607
3' UTR clone of purinergic receptor P2X ligand-gated ion channel 7 (P2RX7) for miRNA target validation
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CNY 5464.00
货期*
                        现货
                    规格
                        | Cited in 3 publications. | 
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                Specifications
| Product Data | |
| Product Name | P2RX7 (NM_002562) Human 3' UTR Clone | 
| Vector | pMirTarget | 
| Synonyms | P2X7 | 
| ACCN | NM_002562 | 
| Insert Size | 1276 bp | 
| Sequence Data | >SC213607 3' UTR clone of NM_002562 The sequence shown below is from the reference sequence of NM_002562. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC ACAGTGGCTTCAAGAGTCCTTACTGAAGCCAGGCACCGTGGCTCACGTCTGTAATCCCAGCGCTTTGGGA GGCCGAGGCAGGCAGATCACCTGAGGTCGGGAGTTGGAGACCCGCCTGGCTAACAAGGCGAAATCCTGTC TGTACTAAAAATACAAAAATCAGCCAGACATGGTGGCATGCACCTGCAATCCCAGCTACTCGGGAGGCTG AGGCACAAGAATCACTTGAACCCGGGAGGCAGAGGTTGTAGTGAGCCCAGATTGTGCCACTGCTCTCCAG CCTGGGAGGCACAGCAAACTGTCCCCCAAAAAAAAAAAAGAGTCCTTACCAATAGCAGGGGCTGCAGTAG CCATGTTAACATGACATTTACCAGCAACTTGAACTTCACCTGCAAAGCTCTGTGGCCACATTTTCAGCCA AAGGGAAATATGCTTTCATCTTCTGTTGCTCTCTGTGTCTGAGAGCAAAGTGACCTGGTTAAACAAACCA GAATCCCTCTACATGGACTCAGAGAAAAGAGATTGAGATGTAAGTCTCAACTCTGTCCCCAGGAAGTTGT GTGACCCTAGGCCTCTCACCTCTGTGCCTCTGTCTCCTTGTTGCCCAACTACTATCTCAGAGATATTGTG AGGACAAATTGAGACAGTGCACATGAACTGTCTTTTAATGTGTAAAGATCTACATGAATGCAAAACATTT CATTATGAGGTCAGACTAGGATAATGTCCAACTAAAAACAAACCCTTTTCATCCTGGCTGGAGAATGTGG AGAACTAAAGGTGGCCACAAATTCTTTGACACTCAAGTCCCCCAAGACCTAAGGGTTTTATCTCCTCCCC TTGAATATGGGTGGCTCTGATTGCTTTATCCAAAAGTGGAAGTGACATTGTGTCAGTTTCAGATCCTGAT CTTAAGAGGCTGACAGCTTCTACTTGCTGTCCCTTGGAACTCTTGCTATCGGGGAAGCCAGACGCCATTT AAAAGTCTGCCTATCCTGGCCAGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGACCAAGGC GGGCGGATCACTTAAAGTCAGGAGTCCAAGACCAGACTCGCCAACATGGTGAAACCGTATCTCTAATAAA AATACAAAAATTAGCTGGGCATGGTGCGGGCACCTGTAGTCCTAGCTATCAAGAGGCTGAGACAGGAGAA ACACTTGAACCTGGGAGGTGGAGGTTGCATTGAGCTGAGATCGTGCCACTGCACTCCAGGCTGGGTGACA GAGCGAGACTCCATCT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG | 
| Restriction Sites | SgfI-MluI | 
| OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). | 
| Reference Data | |
| RefSeq | NM_002562.4 | 
| Synonyms | P2X7 | 
| Summary | The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria. [provided by RefSeq, Jul 2010] | 
| Locus ID | 5027 | 
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: | 
|---|
| Diphenyleneiodonium enhances P2X7 dependent non-opsonized phagocytosis and suppresses inflammasome activation via blocking CX43-mediated ATP leakage.
                                                ,null,
                                                Pharmacological research
                                                ,PubMed ID 33529751
                                                [P2RX7] | 
| Distinct shear-induced Ca 2+ signaling in the left and right atrial myocytes: Role of P2 receptor context.
                                                ,null,
                                                Journal of molecular and cellular cardiology
                                                ,PubMed ID 32305361
                                                [P2RX7] | 
| P2X 4 Assembles with P2X 7 and Pannexin-1 in Gingival Epithelial Cells and Modulates ATP-induced Reactive Oxygen Species Production and Inflammasome Activation
                                                ,null,
                                                PLoS ONE
                                                ,PubMed ID 23936165
                                                [P2RX7] | 
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