SMAD1 (NM_005900) Human 3' UTR Clone

Specifications

Product Data
Product Name	SMAD1 (NM_005900) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1
ACCN	NM_005900
Insert Size	1272 bp
Sequence Data	Insert Sequence (showhide) >SC213442 3’UTR clone of NM_005900 The sequence shown below is from the reference sequence of NM_005900. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTCATAATCCTATTTCATCTGTATCTTAAATGGCCCCAGGCATCTGCCTCTGGAAAACTATTGAGCCT TGCATGTACTTGAAGGATGGATGAGTCAGACACGATTGAGAACTGACAAAGGAGCCTTGATAATACTTG ACCTCTGTGACCAACTGTTGGATTCAGAAATTTAAACAAAAAAAAAAAAAAACACACACACCTTGGTAA CATACTGTTGATATCAAGAACCTGTTTAGTTTACATTGTAACATTCTATTGTAAAATCAACTAAAATTC AGACTTTTAGCAGGACTTTGTGTACAGTTAAAGGAGAGATGGCCAAGCCAGGGACAAATTGTCTATTAG AAAACGGTCCTAAGAGATTCTTTGGTGTTTGGCACTTTAAGGTCATCGTTGGGCAGAAGTTTAGCATTA ATAGTTGTTCTGAAACGTGTTTTATCAGGTTTAGAGCCCATGTTGAGTCTTCTTTTCATGGGTTTTCAT AATATTTTAAAACTATTTGTTTAGCGATGGTTTTGTTCGTTTAAGTAAAGGTTAATCTTGATGATATAC ATAATAATCTTTCTAAAATTGTATGCTGACCATACTTGCTGTCAGAATAATGCTAGGCATATGCTTTTT GCTAAATATGTATGTACAGAGTATTTGGAAGTTAAGAATTGATTAGACTAGTGAATTTAGGAGTATTTG AGGTGGGTGGGGGGAAGAGGGAAATGACAACTGCAAATGTAGACTATACTGTAAAAATTCAGTTTGTTG CTTTAAAGAAACAAACTGATACCTGAATTTTGCTGTGTTTCCATTTTTTAGAGATTTTTATCATTTTTT TCTCTCTCGGCATTCTTTTTTCTCATACTCTTCAAAAAGCAGTTCTGCAGCTGGTTAATTCATGTAACT GTGAGAGCAAATGAATAATTCCTGCTATTCTGAAATTGCCTACATGTTTCAATACCAGTTATATGGAGT GCTTGAATTTAATAAGCAGTTTTTACGGAGTTTACAGTACAGAAATAGGCTTTAATTTTCAAGTGAATT TTTTGCCAAACTTAGTAACTCTGTTAAATATTTGGAGGATTTAAAGAACATCCCAGTTTGAATTCATTT CAAACTTTTTAAATTTTTTTGTACTATGTTTGGTTTTATTTTCCTTCTGTTAATCTTTTGTATTCACTT ATGCTCTCGTACATTGAGTACTTTTATTCCAAAACTAGTGGGTTTTCTCTACTGGAAATTTTCAATAAA CCTGTCATTATTGCTTACTTTGATTAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005900.3
Synonyms	BSP-1; BSP1; JV4-1; JV41; MADH1; MADR1
Summary	The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq, Jul 2008]
Locus ID	4086
MW	49.9

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