Kallikrein 7 (KLK7) (NM_005046) Human 3' UTR Clone

Specifications

Product Data
Product Name	Kallikrein 7 (KLK7) (NM_005046) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	hK7; PRSS6; SCCE
ACCN	NM_005046
Insert Size	1098 bp
Sequence Data	Insert Sequence (showhide) >SC212172 3’UTR clone of NM_005046 The sequence shown below is from the reference sequence of NM_005046. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATAAATGACACCATGAAAAAGCATCGCTAACGCCACACTGAGTTAATTAACTGTGTGCTTCCAACAGAA AATGCACAGGAGTGAGGACGCCGATGACCTATGAAGTCAAATTTGACTTTACCTTTCCTCAAAGATATA TTTAAACCAACCTCATGCCCTGTTGATAAACCAATCAAATTGGTAAAGACCTAAAACCAAAACAAATAA AGAAACACAAAACCCTCAGTGCTGGAGAAGAGTCAGTGAGACCAGCACTCTCAAACACTGGAACTGGAC GTTCGTACAGTCTTTACGGAAGACACTTGGTCAACGTACACCGAGACCCTTATTCACCACCTTTGACCC AGTAACTCTAATCTTAGGAAGAACCTACTGAAACAAAAAAAATCCAAAATGTAGAACAAGACTTGAATT TACCATGATATTATTTATCACAGAAATGAAGTGAAACCATCAAACATGTTCCAAAAGTACCAGATGGCT TAAATAATAGTCTGGCTTGGCACAACGATGTTTTTTTTCTTTGAGACAGAGTCTCTGTTGCTTGGGCTG CAATGCAGTGATGCAATCTTGGCTCACTGCAACCTCCGCCTCCTGGGTTCAAGTGATTCTCGTGCTTCA GCCTCCCAAGTACCTGGGACTACAGGTGTGCACCACCACACCAGGCTAATTTTTTGTGTATTTTTACTA GAGACAGGGTTTCACCATGTTGGCCAGCATGGTCTTGAACGCCTGACCTCAGATGATCCACCCACCTTG GCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCACGGCCAGCCCACAATGATATTACAAACCTAT TAAAAATGATACTTAGACAGAATTGTCAGTATTATTCAAGAACATTTAGGCTATAGGATGTTAAATGAC AAAAGGAAGGACAAAAATATATATGTATGTGACCCTACCCATAAAAAATGAAATATTCACAGAATCAGA TCTGAAAACACATGTCCCAGACTGCATACTGGGGTCGTCATGAGGTGTCTCCTTCCTTCTGTGTACTTT TCCTTGAATGTGCACTTTTATAACATGAAAAATAAAGGTGGGGAAAAAAGTCTGAAGATCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005046.4
Synonyms	hK7; PRSS6; SCCE
Summary	This gene encodes a member of the kallikrein subfamily of serine proteases. These enzymes have diverse physiological functions and many kallikrein genes are biomarkers for cancer. The encoded protein has chymotrypsin-like activity and plays a role in the proteolysis of intercellular cohesive structures that precedes desquamation, the shedding of the outermost layer of the epidermis. The encoded protein may play a role in cancer invasion and metastasis, and increased expression of this gene is associated with unfavorable prognosis and progression of several types of cancer. Polymorphisms in this gene may play a role in the development of atopic dermatitis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, which is one of fifteen kallikrein subfamily members located in a gene cluster on chromosome 19. [provided by RefSeq, May 2011]
Locus ID	5650
MW	42.1

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