Neuro D4 (DPF1) (NM_004647) Human 3' UTR Clone

Specifications

Product Data
Product Name	Neuro D4 (DPF1) (NM_004647) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BAF45b; NEUD4; neuro-d4
ACCN	NM_004647
Insert Size	1087 bp
Sequence Data	Insert Sequence (showhide) >SC212125 3’UTR clone of NM_004647 The sequence shown below is from the reference sequence of NM_004647. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGGCTTCTGCTTACATCACCCTCACCTAGGCCGGCTCGGCTCGCCGCGACTCTGGGGTGGTGCTCGCC TACCTGCCTCTCCGAGCTCCTCAATTCTCCCCCACCCTGAACATCCCGCAGGGGGAGGGGGAGAGGGGG AAGCCGAGAGGGGGCTGGGCCACCCCCTCCCCTCTGTGCAAGTGGAATGTCTGCCCTGTGGGTGGGTGG GCCCGGCCAGGGCCTCTCCCTCCCTCCCTCCCTCTCTGTCCCTTGGCAAATGGACACCAGGGGCTTCTC CCCTCAAAGCCATACCCCGCCTCTGGGCGGGCATGGGGGGTGGTGGGTGCCAGCCAGGGGCATGGACAG AGCCTTTTTCTAAAGAAAAAGACAAAAAGTTAAAAAAAAAAAAAAGAAGAAAAGAAAAGAAGTTAATAT ATACAAAGAGTCCTCCAAGGCCTGGCTGGGTGGAGGGGCGCTGCTGAGAGTGTCCACCGGGCACCCGCC TCTGCCGGCCCCCCGCCGGGCGCCCCAACCCCAATTTCTGGAGCTGCAGCCGTCCCGCGCCCCACCCAA GGTGGGCGCCTTCCCCTCTTGTGCCCAGGGCGGTGGGCGTGGTGTCCACCCGCCCCTCCTGGTGCCCAC GGTGGATACTGCATGATGTGAACCTTGGTTTTGAACTCTGTTCCTGCCCCTCCCCGACCGCCCCAGCCT GTGCCCGCCCCGTGCCTGCCGTGGCTGGTGGGTGGCGGTGGTGGGGCCGGGTGGGCCCCCGCCCAGCGC CTGCTGGAATGAGAAGCACAGACTCCGCCACGGACTCCTTTTCTCTCCCTCCTCCCGCCCCGCCAGGCC TGGCGGCCCCCGCCCCCCTCGCTGGCCATTTTGGGGGAGTGAGGGGGCGTGGTTGTTTCTTGTGGTTGT GTGTGTTTGTTGTTCGGGTTTTAAAAAAGGGAAACTGAGACTGCAGGTGGGGGAGGTGGTGGGTTTTGG GGGGATGTCCCCTAATCCAGGAGTGCCCCCTCACTTGTCACCGAGTCTCCTCTATTGCCTGCCTCTGCT GTGAATTAACTTGTTCTGTGTATTAAACTGGGCCTGACCCCTCTGCCCACGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004647.4
Synonyms	BAF45b; NEUD4; neuro-d4
Summary	May have an important role in developing neurons by participating in regulation of cell survival, possibly as a neurospecific transcription factor. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex). During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes. As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF). The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells. The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	8193
MW	37.6

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