RASGRP 4 (RASGRP4) (NM_001146202) Human 3' UTR Clone

CAT#: SC211701

3' UTR clone of RAS guanyl releasing protein 4 (RASGRP4) transcript variant b for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name RASGRP 4 (RASGRP4) (NM_001146202) Human 3' UTR Clone
Vector pMirTarget
ACCN NM_001146202
Insert Size 1012 bp
Sequence Data
>SC211701 3’UTR clone of NM_001146202
The sequence shown below is from the reference sequence of NM_001146202. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
TCAACTGCATCCTCCAAGCTGGATTCCTAGACATCTCTTGGTCTCCTCTCTTCCTCACTCCCTTCCCCC
AGTCAGTCCTGAGTCCTGCCGTCAGACTCTGGCAGGGCTCCCAGAGGTAGGCCTCCAGAGGCATCCGCC
TTCCCATCCACACTGCCTTTAGTGGTACGTCCGTCATCTTTTTCCCTGGAAGTGACTTTCCTCTTTTGC
ATCCTGGTGGATGCTAATCCTGCTCCCTTTCCCTGCACTTAGTATCTGTGCGGCTGTGTGTTGGATACA
TTTAGACTCAGGCCTCATTCTACCAACTCCCTACATCTCCATTTCTTTTTTTTTTTGAGACAGAGTCTT
GCTCTGTCACCCAGGCTGGAGTGCAATGATGCAATCTCAGCTCACTGCAACTTCCGCCTCCTGGGTTCA
AGTGATTCTTCTGCCTCAGCCTCCCAAGTAGCTGGGATTACAGGCACGCGCCACCATGCCCGGCTAATT
TTTGTATTTTTAGTAGAGACGGGGTTTCCCCATGTTGGCCAAGATGGTCTCAAACTCCTGACCTCATGA
TCCACCAGCCTCAGCCTCCCAAAGTGCTGGGAATACAGGCGTGAGCCACCACGCCCAGCTCCTGTTTTT
CTGCATAGAATGTGCTCCCTCTGACAGCCTATACTTTTTCCCTCTTTATCTCGTTGAACGTCTGTCTTT
CCTCAACAGGAGCATCAACTCCAGGAGAACAGGGATTTCTATCAATGTCATTCACTGCTGCATCCCCAG
TGCCTAGAACAGGGCTGGCAGGTGGTAGGCGCCTGACAGATGCTTGTCTGATGCCTGAATGTCTCCTTA
CCCATGCCCACGGCACAGGATAGATGTGCTATAGGGCAAAGAACTTTGAGGGTCGAGCAGCAGGGGCCC
ATTCAGTCCCAGGGAGCAGAGACCCCCCCAACCCCTTCACAAACCCCAACACCCCTGACTTGGCCCCCA
CAGAGAGAGGTCCTACAGCTGTCATAAATTAAATTTATTCTCTGGA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_001146202.2
Summary The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2009]
Locus ID 115727
MW 37.3
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