Hsp22 (HSPB8) (NM_014365) Human 3' UTR Clone

Specifications

Product Data
Product Name	Hsp22 (HSPB8) (NM_014365) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
ACCN	NM_014365
Insert Size	918 bp
Sequence Data	Insert Sequence (showhide) >SC211265 3’UTR clone of NM_014365 The sequence shown below is from the reference sequence of NM_014365. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGACAGCCAGGAAGTCACCTGTACCTGAGATGCCAGTACTGGCCCATCCTTGTTTTGTCCCCAACCC TAGGGCTTCTCTGATTCCAGGATACATTACTTTAGCTGAACTCAGATTTAGTGCAAGTAAAATGTTAGA GGGTGCGGGGGTGAGGACTGACCACAGATTCCCTGGATAGTGTAGTGGTAGATTTCTCCACAGGATAGC GCAATTGGCAAATCATGCTTGGTTGTGTTAGGCCAAAATACTAGTTTTGCTTTCTTTACCTTTTCTATC TTGATGAAAATGTTGCACATTCTATAGTTGCAAAACACATAAAAGGGGACTTAACATTTCACGTTGTAT CTTACTTGCAGTGAATGCAAGGGTTACTTTTCTCTGGGGACCTCCCCCATCACCCAGGTTCCTACTCTG GGCTCCCGATTCCCATGGCTCCCAAACCATGCCGCATGGTTTGGTTAATGAAACCCAGTAGCTAACCCC ACTGTGCTTCCACATGCCTGGCCTAAAATGGGTGATATACAGGTCTTATATCCCCATATGGAATTTATC CATCAACCACATAAAAACAAACAGTGCCTTCTGCCCTCTGCCCAGATGTGTCCAGCACGTTCTCAAAGT TTCCACATTAGCACTCCCTAAGGACGCTGGGAGCCTGTCAGTTTATGATCTGACCTAGGTCCCCCCTTT CTTCTGTCCCCTGTGTTTAAGTCGGGATTTTTACAGAGGGAGCTGTCTCCAGACAGCTCCATCAGGAAC CAAGCAAAGGCCAGATAGCCTGACAGATAGGCTAGTGGTATTGTGTATATGGGCGGGACGTGTGTGTCA TTATTATTTGAGTTATGCTGTTGTTTAGGGGTAAATAACAGTAAATAATTAATAATAATAATAATAATA ATAAAGGAGCTGACGTTCTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014365.3
Synonyms	CMT2L; DHMN2; E2IG1; H11; HMN2; HMN2A; HSP22
Summary	The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
Locus ID	26353
MW	34

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